Publikationen

2019

Abshagen K, Mense L, Fischer F, Liebig M, Schaeper U, Navarro G, Glass Ä, Frank M, Klöting N, Vollmar B. Repin1 deficiency in liver tissue alleviates NAFLD progression in mice. J Adv Res. 2018 Nov 22;16:99-111.


Beyer F, García-García I, Heinrich M, Schroeter ML, Sacher J, Luck T, Riedel-Heller SG, Stumvoll M, Villringer A, Witte AV. Neuroanatomical correlates of food addiction symptoms and body mass index in the general population. Hum Brain Mapp. 2019 Feb 28.


Blüher M. Obesity: global epidemiology and pathogenesis. Nat Rev Endocrinol. 2019 Feb 27.


Breitfeld J, Wiele N, Gutsmann B, Stumvoll M, Blüher M, Scholz M, Kovacs P, Tönjes A. Circulating Adipokine VASPIN Is Associated with Serum Lipid Profiles in Humans. Lipids. 2019 Mar 18.


García-Cáceres C, Balland E, Prevot V, Luquet S, Woods SC, Koch M, Horvath TL, Yi CX, Chowen JA, Verkhratsky A, Araque A, Bechmann I, Tschöp MH. Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism. Nat Neurosci. 2019 Jan;22(1):7-14.


Goldstein N, Haim Y, Mattar P, Hadadi-Bechor S, Maixner N, Kovacs PBlüher MRudich A. Leptin stimulates autophagy/lysosome-related degradation of long-lived proteins in adipocytes. Adipocyte. 2019 Jan 24.


Joost E, Jordão MJC, Mages B, Prinz M, Bechmann I, Krueger M. Microglia contribute to the glia limitans around arteries, capillaries and veins under physiological conditions, in a model of neuroinflammation and in human brain tissue. Brain Struct Funct. 2019 Jan 31.


Kögler LM, Stichel J, Kaiser A, Beck-Sickinger AG. Cell-Free Expression and Photo-Crosslinking of the Human Neuropeptide Y2 Receptor. Front Pharmacol. 2019 Mar 1;10:176.


Kosacka J, Woidt K, Toyka KV, Paeschke S, Klöting NBechmann IBlüher M, Thiery J, Ossmann S, Baum P, Nowicki M. The role of dietary non-heme iron load and peripheral nerve inflammation in the development of peripheral neuropathy (PN) in obese non-diabetic leptin-deficient ob/ob mice. Neurol Res. 2019 Jan 13:1-13.


Lampe L, Zhang R, Beyer F, Huhn S, Kharabian Masouleh S, Preusser S, Bazin PL, Schroeter ML, Villringer A, Witte AV. Visceral obesity relates to deep white matter hyperintensities via inflammation. Ann Neurol. 2019 Feb;85(2):194-203.


Mancini G, Pirruccio K, Yang X, Blücher M, Rodeheffer M, Horvath TL., Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight. Cell Rep. 2019 Mar 12;26(11):2849-2858.e4.


Mandić AD, Woting A, Jaenicke T, Sander A, Sabrowski W, Rolle-Kampcyk U, von Bergen M, Blaut M. Clostridium ramosum regulates enterochromaffin cell development and serotonin release. Sci Rep. 2019 Feb 4;9(1):1177.


Püschel J, Miehle K, Müller K, Villringer AStumvoll MFasshauer M, Schlögl H. Beneficial effects of leptin substitution on impaired eating behavior in lipodystrophy are sustained beyond 150 weeks of treatment. Cytokine. 2019 Jan;113:400-404.


Röthe J, Thor D, Winkler J, Knierim AB, Binder C, Huth S, Kraft R, Rothemund S, Schöneberg T, Prömel S. Involvement of the Adhesion GPCRs Latrophilins in the Regulation of Insulin Release. Cell Rep. 2019 Feb 5;26(6):1573-1584.


Schöneberg T, Prömel S. Latrophilins and Teneurins in Invertebrates: No Love for Each Other? Front. Neurosci., 12 March 2019


Wagner R, Dittrich J, Thiery J, Ceglarek UBurkhardt R. Simultaneous LC-MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma. J Lipid Res. 2019 Feb 5. pii: jlr.D084301


Yaskolka Meir A, Tsaban G, Zelicha H, Rinott E, Kaplan A, Youngster I, Rudich A, Shelef I, Tirosh A, Brikner D, Pupkin E, Sarusi B, Blüher M, Stümvoll M, Thiery J, Ceglarek U, Stampfer MJ, Shai I. A Green-Mediterranean Diet, Supplemented with Mankai Duckweed, Preserves Iron-Homeostasis in Humans and Is Efficient in Reversal of Anemia in Rats. J Nutr. 2019 Mar 27. pii: nxy321.

2018

Abshagen K, Degenhardt B, Liebig M, Wendt A, Genz B, Schaeper U, Stumvoll M, Hofmann U, Frank M, Vollmar B, Klöting N. Liver-specific Repin1 deficiency impairs transient hepatic steatosis in liver regeneration. Sci Rep. 2018 Nov 15;8(1):16858.


Arndt L, Burkhardt R. Lipid metabolism: spotlight on modulators of lipoprotein lipase activity. Curr Opin Lipidol. 2018 Apr;29(2):164-165


Arndt L, Dokas J, Gericke M, Kutzner CE, Müller S, Jeromin F, Thiery J, Burkhardt R. Tribbles homolog 1 deficiency modulates function and polarization of murine bone marrow-derived macrophages. J Biol Chem. 2018 Jun 13. pii: jbc.RA117.000703.


Bartels MS, Scheffler L, Chakaroun R, Dietrich A, Blüher M, Stumvoll M, Tönjes A, Breitfeld J, Kovacs P. Increased circulating cell-free DNA in insulin resistance.Diabetes Metab. 2018 Jun 20.


Boura-Halfon S, Pecht T, Jung S, Rudich A. Obesity and dysregulated central and peripheral Macrophage-neuron crosstalk. Eur J Immunol. 2018 Nov 8.


Dittrich J, Beutner F, Teren A, Thiery J, Burkhardt R, Scholz M, Ceglarek U. Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease. Atherosclerosis. 2018 Nov 9;281:17-24.


Ditz T, Schnapka-Hille L, Noack N, Dorow J, Ceglarek U, Niederwieser D, Schiller J, Fuchs B, Cross M. Phospholipase A2 products predict the hematopoietic support capacity of horse serum. Differentiation. 2018 Dec 6;105:27-32. 


Ebert T, Gebhardt C, Scholz M, Wohland T, Schleinitz D, Fasshauer M, Blüher M, Stumvoll M, Kovacs P, Tönjes A. Relationship between twelve adipocytokines and distinct components of the metabolic syndrome. JClinEndocrinol Metab. 2018: 10.1210/jc.2017-02085.


Engel K, Griesinger H, Schulz M, Schiller J.Normal Phase versus Reversed Phase TLC to monitor Oxidized Phosphatidylcholines by TLC/Mass Spectrometry. Rapid Commun Mass Spectrom. 2018 Jul 18.


Erbs S, Broniecki H, Scheuermann K, Winzer E, Adam J, Spielau U, Woitek F, Sandri M, Zimmer M, Besler C, Kiess W, Linke A, Körner A, Mangner N. Impact of Weight Reduction During Adolescence on Parameters of Cardiac Geometry and Function in Obese Children. JACC Cardiovasc Imaging. 2018 Jul 13.


Geserick M, Vogel M, Gausche R, Lipek T, Spielau U, Keller E, Pfäffle R, Kiess WKörner A. Acceleration of BMI in Early Childhood and Risk of Sustained Obesity. N Engl J Med. 2018 Oct 4;379(14):1303-1312.


Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Blüher M, Czech MP, Tabas I.Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance. Nature. 2018 Mar 29;555(7698):673-677.


Giusepponi ME, Kern M, Chakaroun R, Wohland T, Kovacs P, Dietrich A, Schön MR, Krohn K, Pucci M, Polidori C, Micioni Di Bonaventura MV, Stumvoll MBlüher M, Cifani C, Klöting N. Gene expression profiling in adipose tissue of Sprague Dawley rats identifies olfactory receptor 984 as a potential obesity treatment target. Biochem Biophys Res Commun. 2018 Nov 2;505(3):801-806.


Grohmann T, Penke M, Petzold-Quinque S, Schuster S, Richter S, Kiess WGarten A. Inhibition of NAMPT sensitizes MOLT4 leukemia cells for etoposide treatment through the SIRT2-p53 pathway. Leukemia Res. 2018 Jun,69, 39–46.


Haimon Z, Volaski A, Orthgiess J, Boura-Halfon S, Varol D, Shemer A, Yona S, Zuckerman B, David E, Chappell-Maor L, Bechmann IGericke M, Ulitsky I, Jung S., Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies. Nat Immunol. 2018 May 18.


Hankir MH, Klingenspor M. Brown adipocyte glucose metabolism: a heated subject. EMBO Rep. 2018 Aug 22. pii: e46404.


Hankir MH, Seyfried F,  Miras AD, Cowley MA. Brain Feeding Circuits after Roux-en-Y Gastric Bypass.Trends Endocrinol Metab. 2018 Feb 20: S1043-2760(18)30018-3.


Hardikar S, Wallroth R, Villringer A, Ohla K. Shorter-lived neural taste representations in obese compared to lean individuals. Sci Rep. 2018 Jul 23;8(1):11027.


Hellrung L, Dietrich A, Hollmann M, Pleger B, Kalberlah C, Roggenhofer E, Villringer AHorstmann A. Intermittent compared to continuous real-time fMRI neurofeedback boosts control over amygdala activation. Neuroimage. 2018 Feb 1;166:198-208.


Herbert D, Franz S, Popkova Y, Anderegg U, Schiller J, Schwede K, Lorz A, Simon JC, Saalbach A. High fat diet exacerbates early psoriatic skin inflammation independent of obesity: Saturated fatty acids as key players. J Invest Dermatol. 2018 Mar 29.


Hoffmann A, Ebert T, Klöting N, Kolb M, Gericke M, Jeromin F, Jessnitzer B, Lössner U, Burkhardt R, Stumvoll M, Fasshauer M, Kralisch S. Leptin decreases circulating inflammatory IL-6 and MCP-1 in mice. Biofactors. 2018 Nov 29.


Hollenbach M, Klöting N, Sommerer I, Lorenz J, Heindl M, Kern M, Mössner J, Blüher M, Hoffmeister A. p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet. PLoS One. 2018 Jul 24


Horn H, Böhme B, Dietrich L, Koch M. Endocannabinoids in Body Weight Control. Pharmaceuticals (Basel). 2018 May 30;11(2).


Huhn S, Beyer F, Zhang R, Lampe L, Grothe J, Kratzsch J, Willenberg A, Breitfeld J, Kovacs PStumvoll M, Trampel R, Bazin PL, Villringer AWitte AV. Effects of resveratrol on glucose, memory and the hippocampus - a randomized controlled trial. Neuroimage. 2018 Mar 13;174:177-190.


Junge KM, Leppert B, Jahreis S, Wissenbach DK, Feltens R, Grützmann K, Thürmann L, Bauer T, Ishaque N, Schick M, Bewerunge-Hudler M, Röder S, Bauer M, Schulz A, Borte M, Landgraf K, Körner A, Kiess Wvon Bergen M, Stangl GI, Trump S, Eils R, Polte T, Lehmann I. MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development. Clin Epigenetics. 2018 Apr 20;10:58.


Kaplan A, Zelicha H, Tsaban G, Yaskolka Meir A, Rinott E, Kovsan J, Novack L, Thiery J, Ceglarek U, Burkhardt R, Willenberg A, Tirosh A, Cabantchik I, Stampfer MJ, Shai I. Protein bioavailability of Wolffia globosa duckweed, a novel aquatic plant, - A randomized controlled trial. Clin Nutr. 2018 Dec 11. pii: S0261-5614(18)32577-9. 


Kässner F, Sauer T, Penke M, Richter S, Landgraf K, Körner AKiess W, Händel N, Garten A. Simvastatin induces apoptosis in PTEN‑haploinsufficient lipoma cells. Int J Mol Med. 2018 Mar 14.


Keller M, Klös M, Rohde K, Krüger J, Kurze T, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll MBlüher M, Kovacs P, Böttcher Y. DNA methylation of SSPN is linked to adipose tissue distribution and glucose metabolism. FASEB J. 2018 Jun 22:fj201800528R.


Kratochvil I, Hofmann T, Rother S, Schlichting R, Moretti R, Scharnweber D, Hintze V, Escher BI, Meiler J, Kalkhof S, von Bergen M. MEHP and MEOHP but not DEHP bind productively to the peroxisome proliferator-activated receptor γ. Rapid Commun Mass Spectrom. 2018 Aug 7.


Krüger J, Berger C, Weidle K, Schleinitz D, Tönjes A, Stumvoll MBlüher M, Kovacs P, Klöting N. Metabolic effects of genetic variation in the human REPIN1 gene. Circ Genom Precis Med. 2018 May;11(5):e001992.


Kumar S, Grundeis F, Brand C, Hwang HJ, Mehnert J, Pleger B. Satiety-induced enhanced neuronal activity in the frontal operculum relates to the desire for food in the obese female brain. Exp Brain Res. 2018 Jun 22.


Lalem T, Zhang L, Scholz M, Burkhardt R, Saccheti V, Teren A, Thiery J, Devaux Y; Cardiolinc™ network (www.cardiolinc.org). Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction. Int J Cardiol. 2018 Jul 10. pii: S0167-5273(18)32556-7.


Lampe L, Zhang R, Beyer F, Huhn S, Kharabian-Masouleh S, Preusser S, Bazin PL, Schroeter ML, Villringer A, Witte AV. Visceral Obesity Relates to Deep White Matter Hyperintensities via Inflammation. Ann Neurol. 2018 Dec 17. 


Langhardt J, Flehmig G, Klöting N, Lehmann S, Ebert T, Kern M, Schön MR, Gärtner D, Lohmann T, Dressler M, Fasshauer M, Kovacs P, Stumvoll M, Dietrich A, Blüher M. Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity. Obes Facts. 2018;11(6):475-490.


Leopold J, Popkova Y, Engel KM, Schiller J. Visualizing phosphatidylcholine via mass spectrometry imaging: relevance to human health. Expert Rev Proteomics. 2018 Sep 21.


Leopold J, Popkova Y, Engel KM, Schiller J. Recent Developments of Useful MALDI Matrices for the Mass Spectrometric Characterization of Lipids. Biomolecules. 2018 Dec 13;8(4). 


Mehl N, Mueller-Wieland L, Mathar D, Horstmann A. Retraining automatic action tendencies in obesity.Physiol Behav. 2018 Mar 30. pii: S0031-9384(18)30154-9.


Meemken MT, Kube J, Wickner C, Horstmann A. Keeping track of promised rewards: Obesity predicts enhanced flexibility when learning from observation. Appetite. 2018 Dec 1;131:117-124.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Serum concentrations of fetuin B in lipodystrophic patients. Cytokine. 2018 Jun;106:165-168.


Morys F, Bode S, Horstmann A. Dorsolateral and medial prefrontal cortex mediate the influence of incidental priming on economic decision making in obesity. Sci Rep. 2018 Dec 4;8(1):17595.


Nickel A, Blücher C, Kadri OA, Schwagarus N, Müller S, Schaab M, Thiery J, Burkhardt R, Stadler SC. Adipocytes induce distinct gene expression profiles in mammary tumor cells and enhance inflammatory signaling in invasive breast cancer cells. Sci Rep. 2018 Jun 21;8(1):9482.


Pott J, Schlegel V, Teren A, Horn K, Kirsten H, Bluecher C, Kratzsch J, Loeffler M, Thiery J, Burkhardt R, Scholz M.Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes. Circ Genom Precis Med. 2018 May;11(5):e001992.


Reinicke M, Schröter J, Müller-Klieser D, Helmschrodt C, Ceglarek U. Free oxysterols and bile acids including conjugates-Simultaneous quantification in human plasma and cerebrospinal fluid by liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta, march 2018


Rodriguez FS, Schroeter ML, Arélin K, Witte AV, Baber R, Burkhardt R, Engel C, Löffler M, Thiery J, Villringer A, Luck T, Riedel-Heller SG. APOE e4-genotype and lifestyle interaction on cognitive performance: Results of the LIFE-Adult-study. Health Psychol. 2018 Feb;37(2):194-205.


Rohde K, Keller M, la Cour Poulsen L, Blüher M, Kovacs P, Böttcher Y. Genetics and epigenetics in obesity. Metabolism. 2018 Nov 3. pii: S0026-0495(18)30225-7.


Scheffler L, Crane A, Heyne H, Tönjes A, Schleinitz D, Ihling HC, Stumvoll M, Freire R, Fiorentino M, Fasano A, Kovacs P and Heiker JT. Widely Used commercial elisa. Does not Detect Precursor of haptoglobin2, but recognizes Properdin as a Potential second Member of the Zonulin Family. Front Endocrinol (Lausanne). 2018 Feb 5;9:22 .


Schmidt E, Dhaouadi I, Gaziano I, Oliverio M, Klemm P, Awazawa M, Mitterer G, Fernandez-Rebollo E, Pradas-Juni M, Wagner W, Hammerschmidt P, Loureiro R, Kiefer C, Hansmeier NR, Khani S, Bergami M, Heine M, Ntini E, Frommolt P, Zentis P, Ørom UA, Heeren J, Blüher M, Bilban M, Kornfeld JW. LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat. Nat Commun. 2018 Sep 6;9(1):3622


Schöneberg T, Meister J, Knierim AB, Schulz A. The G protein-coupled receptor GPR34 - The past 20 years of a grownup. Pharmacol Ther. 2018 Apr 22. pii: S0163-7258(18)30071-8.


Schröter J, Fülöp A, Hopf C, Schiller J. The combination of 2,5-dihydroxybenzoic acid and 2,5-dihydroxyacetophenone matrices for unequivocal assignment of phosphatidylethanolamine species in complex mixtures. Anal Bioanal Chem.2018 Mar;410(9):2437-2447.


Schwarz C, Wirth M, Gerischer L, Grittner U, Witte AV, Köbe T, Flöel A. Effects of Omega-3 Fatty Acids on Resting Cerebral Perfusion in Patients with Mild Cognitive Impairment: A Randomized Controlled Trial. J Prev Alzheimers Dis. 2018;5(1):26-30.


Sociali G, Grozio A, Caffa I, Schuster S, Becherini P, Damonte P, Sturla L, Fresia C, Passalacqua M, Mazzola F, Raffaelli N, Garten A, Kiess W, Cea M, Nencioni A, Bruzzone S. SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells. FASEB J. 2018 Dec 4:fj201800321R.


Spiller S, Li Y, Blüher M, Welch L, Hoffmann R. Diagnostic Accuracy of Protein Glycation Sites in Long-Term Controlled Patients with Type 2 Diabetes Mellitus and Their Prognostic Potential for Early Diagnosis. Pharmaceuticals (Basel). 2018 Apr 30;11(2)


Spiller S, Blüher M, Hoffmann R. Plasma levels of free fatty acids correlate with type 2 diabetes mellitus. Diabetes Obes Metab. 2018 Jun 25.


Streit WJ, Braak H, Del Tredici K, Leyh J, Lier J, Khoshbouei H, Eisenlöffel C, Müller W, Bechmann I. Microglial activation occurs late during preclinical Alzheimer's disease. Glia. 2018 Nov 11.


Tene L, Shelef I, Schwarzfuchs D, Gepner Y, Yaskolka Meir A, Tsaban G, Zelicha H, Bilitzky A, Komy O, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Chassidim Y, Sarusy B, Ceglarek UStumvoll MBlüher MThiery J, Stampfer MJ, Rudich AShai I. The effect of long-term weight-loss intervention strategies on the dynamics of pancreatic-fat and morphology: An MRI RCT study.Clin Nutr ESPEN. 2018 Apr;24:82-89.


Tönjes A, Scholz M, Krüger J, Krause K, Schleinitz D, Kirsten H, Gebhardt C, Marzi C, Grallert H, Ladenvall C, Heyne H, Laurila E, Kriebel J, Meisinger C, Rathmann W, Gieger C, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Fischer-Rosinsky A, Pfeiffer A, Krohn K, Spranger J, Thiery JBlüher MStumvoll MKovacs P. Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin. Hum Mol Genet. 2018 Feb 1;27(3):546-558.


Ulbricht D, Tindall CA, Oertwig K, Hanke S, Sträter N, Heiker JT. Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin. Biological Chemistry  2018 Feb 1.


Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, Bülow R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Valdés Hernández MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.Nat Commun. 2018 Nov 23;9(1):4960.


Vorselen D, van Dommelen SM, Sorkin R, Piontek MC, Schiller J, Döpp ST, Kooijmans SAA, van Oirschot BA, Versluijs BA, Bierings MB, van Wijk R, Schiffelers RM, Wuite GJL, Roos WH.The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis. Nat Commun. 2018 Nov 23;9(1):4960.


Wagner IV, Sahlin L, Savchuk I, Klöting N, Svechnikov K, Söder O. Adipose Tissue is a Potential Source of Hyperandrogenism in Obese Female Rats. Obesity (Silver Spring). 2018 Jul;26(7):1161-1167.


Wanka L, Babilon S, Kaiser A, Mörl K, Beck-Sickinger AG.Different mode of arrestin-3 binding at the human Y1 and Y2 receptor.Cell Signal. 2018 Jun 23. pii: S0898-6568(18)30130-X.


Weiner J, Zieger K, Pippel J, Heiker JT. Molecular mechanisms of vaspin action – from adipose tissue to skin and bone, from blood vessels to the brain. Adv Exp Med Biol. 2018 Jul 27.


Wistehube T, Rullmann M, Wiacek C, Braun P, Pleger B. Fat perception in the human frontal operculum, insular and somatosensory cortex. Sci Rep. 2018 Aug 7;8(1):11825.


Zhang R, Beyer F, Lampe L, Luck T, Riedel-Heller SG, Loeffler M, Schroeter ML, Stumvoll MVillringer A, Witte AV. White matter microstructural variability mediates the relation between obesity and cognition in healthy adults. Neuroimage. 2018 Feb 2;172:239-249.


Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B. Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor. Nature. 2018 Apr;556(7702):520-524.

2017

Albrecht F, Bisenius S, Morales Schaack R, Neumann J, Schroeter ML. Disentangling the neural correlates of corticobasal syndrome and corticobasal degeneration with system and quantitative ALE meta-analyses. NPJ Parkinsons Dis. 2017;3:12.


Bechor S, Nachmias D, Elia N, Haim Y, Vatarescu M, Leikin-Frenkel A, Gericke M, Tarnovsky T, Las G, Rudich A. Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux. Biochim Biophys Acta. 2017;1862:1001-12.


Braune J, Weyer U, Hobusch C, Mauer J, Brüning J, Bechmann IGericke M. IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophes in obesity. J Immunol. 2017;198:2927-34.


Braune J, Weyer U, Matz-Soja M, Hobusch C, Kern M, Kunath A, Klöting N, Kralisch S, Blüher M, Gebhardt R, Zavros Y, Bechmann IGericke M. Hedgehog sinaling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism. Diabetologia. 2017;6:889-99.


Buerger F, Müller S, Ney N, Weiner J, Heiker JT, Kallendrusch S, Kovacs P, Schleinitz D, Thiery J, Stadler SC, Burkhardt R. Depletion of Jmjd1c impairs adipogenesis in murine 3T3-L1 cells. Biochim Biophys Acta. 2017;1863:1709-17.


Engel KM, Schiller J. A comparison of PC oxidation products as detected by MALDI-TOF and ESI-IT mass spectrometry. Chem Phys Lipids. 2017;203:33-45.


Engel KM, Schiller J, Müller K, Dannenberger D, Jakop U. The phospholipid composition of kangaroo spermatozoa verified by mass spectrometric lipid analysis. Lipids. 2017;52:857-69.


Gepner Y, Shelef I, Schwarzfuchs D, Cohen N, Bril N, Rein M, Tsaban G, Zelicha H, Yaskolka Meir A, Tene L, Sarusy B, Rosen P, Hoffman JR, Stout JR, Thiery J, Ceglarek U, Stumvoll M, Blüher M, Stampfer MJ, Shai I. Intramyocellular triacylglycerol accumulation across weight loss strategies; Sub-study of the CENTRAL trial. PLoS One. 2017;12:e0188431.


Gepner Y, Shelef I, Schwarzfuchs D, Zelicha H, Tene L, Yaskolka Meir A, Tsaban G, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Komy O, Wolak A, Chassidim Y, Golan R, Avni-Hassid H, Bilitzky A, Sarusi B, Goshen E, Shemesh E, Henkin Y, Stumvoll MBlüher MThiery JCeglarek URudich A, Stampfer MJ, Shai I. Effect of distinct lifestyle interventions on mobilization of fast storage pools: the CENTRAL MRI randomized control trial. Circulation. 2017; Epub ahead of print.


Gepner Y, Shelef I, Schwarzfuchs D, Cohen N, Bril N, Rein M, Tsaban G, Zelicha H, Yaskolka Meir A, Tene L, Sarusy B, Rosen P, Hoffman JR, Stout JR, Thiery J, Ceglarek U, Stumvoll M, Blüher M, Stampfer MJ, Shai I. Intramyocellular triacylglycerol accumulation across weight loss strategies; Sub-study of the CENTRAL trial. PLoS One. 2017;12(11):e0188431


Gesing J, Scheuermann K, Wagner IV, Löffler D, Friebe D, Kiess W, Schuster V, Körner A. NAMPT serum levels are selectively elevated in acute infectious disease and in acute relapse of chronic inflammatory diseases in children. PLoS One. 2017;12:e0183027.


Gross A, Tönjes A, Scholz M. On the impact of relatedness on SNP association analysis. BMC Genet. 2017;18:104.


Grundeis F, Brand C, Kumar S, Rullmann M, Mehnert J, Pleger B. Non-invasive prefrontal/frontal brain stimulation is not effective in modulating food reappraisal abilities or calorie consumption in obese females. Front Neurosci. 2017;11:334.


Haim Y, Blüher M, Konrad D, Goldstein N, Klöting N, Harman-Boehm I, Kirshtein B, Ginsberg D, Tarnovscki T, Gepner Y, Shai I, Rudich A. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tisue in obesity, molecularly defining a human dys-metabolic obese phenotype. Mol Metab. 2017;6:725-36.


Hankir MK, Kranz M, Keipert S, Weiner J, Andreasen SG, Kern M, Patt M, Klöting NHeiker JT, Hesse S, Brust P, Jastroch M, Fenske W. Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein 1 deficient mice. J Nucl Med. 2017;58:1100-3.


Hankir M. Loading and firing the brown adipocyte. Adipocyte. 2017; Epub ahead of print.


Hardikar S, Höchenberger R, Villringer A, Ohla K. Higher sensitivity to sweet and salty taste in obese compared to lean individuals. Appetite. 2017;111:158-65.


Hellrung L, Dietrich A, Hollmann M, Pleger B, Kalberlah C, Roggenhofer E, Villringer AHorstmann A. Intermittent compared to continuous real-time fMRI neurofeedback boosts control over amygdala activation. NeuroImage. 2017;166:198-208.


Hesselbarth N, Kunath A, Kern M, Gericke M, Mejhert N, Ryden M, Stumvoll MBlüher MKlöting N. Repin1 deficiency in adipose tissue improves whole-body insulin sensitivity, and lipid metabolism. Int J Obes (Lond). 2017; Epub ahead of print.


Kalenda A, Landgraf K, Löffler D, Kovacs PKiess WKörner A. The BDNF Val66Met polymorphism is associated with lower BMI, lower postprandial glucose levels and elevated carbohydrate intake in children and adolescents. Pediatr Obes. 2017; Epub ahead of print.


Kastner L, Kube J, Villringer ANeumann J. Cardiac concomitants of feedback and prediction error processing in reinforcement learning. Front Neurosci. 2017;11:598.


Kharabian Masouleh S, Beyer F, Lampe L, Loeffler M, Luck T, Riedel-Heller SG, Schroeter ML, Stumvoll MVillringer A, Witte AV. Gray matter structural networks are associated with cardiovascular risk factors in healthy older adults. J Cereb Blood Flow Metab. 2017; Epub ahead of print.


Koch M. Cannabinoid receptor signaling in central regulation of feeding behavior: a mini-review. Front Neurosci. 2017;11:293.


Kralisch S, Hoffmann A, Kratzsch J, Blüher MStumvoll MFasshauer M, Ebert T. The brown-fat-secreted adipokine neuregulin 4 is decreased in gestational diabetes mellitus. Diabetes Metab. 2017; Epub ahead of print.


Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher M, Zhang MZ, Harris RC, Stumvoll MFasshauer M, Ebert T. FSTL3 is increased in renal dysfunction. Nephrol Dial Transplant. 2017;32:1637-44.


Kube J, Mathar D, Horstmann A, Villringer A, Neumann J. Altered monetary loss processing and reinforcement-based learning in individuals with obesity. Brain Imaging Behav. 2017; in press.


Landgraf K, Schuster S, Meusel A, Garten A, Riemer T, Schleinitz D, Kiess WKörner A. Short-term overfeeding of zebrafish with normal or high-fat diet as a model for the development of metabolically healthy versus unhealthy obesity. BMC Physiol. 2017;17:4.


Lede V, Meusel A, Garten A, Popkova Y, Penke M, Franke C, Ricken A, Schulz AKiess WHuster DSchöneberg TSchiller J. Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor. PLoS One. 2017;12:e0172000.


Löffler A, Luck T, Then FS, Luck-Sikorski C, Pabst A, Kovacs P, Böttcher Y, Breitfeld J, Tönjes AHorstmann A, Löffler M, Engel C, Thiery JVillringer AStumvoll M, Riedel-Heller SG. Effects of psychological eating behaviour domains on the association between socio-economic status and BMI. Public Health Nutr. 2017;20:2706-12.


Mathar D, Neumann JVillringer AHorstmann A. Failing to learn from negative prediction errors: Obesity is associated with alterations in a fundamental neural learning mechanism. Cortex. 2017;95:222-37.


Mehl N, Bergmann S, Klein AM, Daum M, von Klitzing K, Horstmann A. Cause or consequence? Investigating attention bias and self-regulation skills in children at risk for obesity. J Exp Child Psychol. 2017;155:113-27.


Meir AY, Tene L, Cohen N, Shelef I, Schwarzfuchs D, Gepner Y, Zelicha H, Rein M, Bril N, Serfaty D, Kenigsbuch S, Chassidim Y, Sarusy B, Dicker D, Thiery JCeglarek UStumvoll MBlüher M, Stampfer MJ, Rudich AShai I. Intrahepatic fat, abdominal adipose tissues, and metabolic state; magnetic resonance imaging study. Diabetes Metab Res Rev. 2017;32.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Adipocyte and epidermal fatty acid-binding protein serum concentrations in patients with lipodystrophy. Cytokine. 2017;92:20-3.


Oertwig K, Ulbricht D, Hanke S, Pippel J, Bellmann-Sickert K, Sträter NHeiker JT. Glycosylation of human vaspin (SERPINA12) and its impact on serpin activity, heparin binding and thermal stability. Biochim Biophys Acta. 2017;1865:1100-3.


Penke M, Schuster S, Gorski T, Gebhardt R, Kiess WGarten A. Oleate ameliorates palmite-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells. Lipids Health Dis. 2017;16:191.


Polyakova M, Schlögl H, Sacher J, Schmidt-Kassow M, Kaiser J, Stumvoll M, Kratzsch J, Schroeter ML. Stability of BDNF in human samples stored up to 6 months and correlations of serum and EDTA-plasma concentrations. Int J Mol Sci. 2017;18:1189.


Popkova Y, Schiller J. TAG suppression by CsCl addition. Rapid Commun Mass Spetrom. 2017;31:411-8.


Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrabě de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH. Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. Cell Metab. 2017;26:620-32.


Raulien N, Friedrich K, Strobel S, Rubner S, Baumann S, von Bergen MKörner A, Krueger M, Rossol M, Wagner U. Fatty acid oxidation compensates for lipopolysaccharide-induced Warburg effect in glucose-deprived monocytes. Front Immunol. 2017;8:609.


Rodriguez FS, Schroeter ML, Witte AV, Engel C, Löffler M, Thiery JVillringer A, Luck T, Riedel-Heller SG. Could high mental demands at work offset the adverse association between social isolation and cognitive functioning? Results of population-based LIFE-adult-study. Am J Geriatr Psychiatry. 2017;25:1258-69.


Rohde K, Klös M, Hopp L, Liu X, Keller M, Stumvoll M, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Kovacs P, Binder H, Blüher M, Böttcher Y. IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits. Sci Rep. 2017;7:12369.


Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. 2017; Epub ahead of print.


Rullmann M, Preusser S, Poppitz S, Heba S, Hoyer J, Schütz T, Dietrich A, Müller K, Pleger B. Gastric-bypass surgery induced widespread neural plasticity of the obese human brain. Neuroimage. 2017; Epub ahead of print.


Schrimpf A, Kube J, Neumann JHorstmann AVillringer A, Gaebler M. Parasympathetic cardio-regulation during social interactions in individuals with obesity - The influence of negative body image. Cogn Affect Behav Neurosci. 2017;17:330-47.


Schröter J, Schiller J. Chlorinated phospholipids and fatty acids: (Patho)Physiological relevance, potential toxicity, and analysis of lipid chlorohydrins. Oxid Med Cell Longev. 2016;2016:8386362.


Tönjes A, Scholz M, Krüger J, Krause K, Schleinitz D, Kirsten H, Gebhardt C, Marzi C, Grallert H, Ladenvall C, Heyne H, Laurila E, Kriebel J, Meisinger C, Rathmann W, Gieger C, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Fischer-Rosinsky A, Pfeiffer A, Krohn K, Spranger J, Thiery J, Blüher M, Stumvoll M, Kovacs P. Genome wide meta-analysis identifies novel determinants of circulating serum progranulin. Hum Mol Genet. 2017; Epub ahead of print.


Tsaban G, Wolak A, Avni-Hassid H, Gepner Y, Shelef I, Henkin Y, Schwarzfuchs D, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Tene L, Zelicha H, Yaskolka-Meir A, Komy O, Bilitzky A, Chassidim Y, Ceglarek UStumvoll MBlüher MThiery J, Dicker D, Rudich A, Stamper MJ, Shai I. Dynamics of intrapericardial and extrapericardial fat tissues during long-term, dietary-induced, moderate weight loss. Am J Clin Nutr. 2017;106:984-95.


Ulbricht D, Oertwig K, Arnsburg K, Saalbach A, Pippel J, Sträter NHeiker JT. Basic residues of ß-sheet a contribute to heparin binding and activation of vaspin (serpin A12). J Biol Chem. 2017;292:994-1004.


Vorselen D, van Dommelen SM, Sorkin R, Piontek MC, Schiller J, Döpp ST, Kooijmans SAA, van Oirschot BA, Versluijs BA, Bierings MB, van Wijk R, Schiffelers RM, Wuite GJL, Roos WH. The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis. Nat Commun. 2018 Nov 23;9(1):4960.


Wanka L, Babilon S, Burkert K, Mörl K, Gurevich VV, Beck-Sickinger AG. C-terminal motif of human neuropeptide Y4 receptor determines internalization and arrestin recruitment. Cell Signal. 2017;29:233-9.


Weiner J, Rohde K, Krause K, Zieger K, Klöting N, Kralisch S, Kovacs PStumvoll MBlüher M, Böttcher Y, Heiker JT. Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation. Mol Met. 2017;6:482-93.


Weise CM, Piaggi P, Reinhardt M, Chen K, Savage CR, Krakoff J, Pleger B. The obese brain as a heritable phenotype - A combined morphometry and twin study. Int J Obes (Lond). 2017;41:458-66.


Windholz J, Kovacs P, Schlicke M, Franke C, Mahajan A, Morris AP, Lemke JR, Klammt J, Kiess WSchöneberg T, Pfäffle R, Körner A. Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. J Pediatr Endocrinol Metab. 2017;30:507-15.


Zelicha H, Schwarzfuchs D, Shelef I, Gepner Y, Tsaban G, Tene L, Yaskolka Meir A, Bilitzky A, Komy O, Cohen N, Bril N, Rein M,Serfaty D, Kenigsbuch S, Chassidim Y, Sarusi B, Thiery J, Ceglarek U, Stumvoll M, Blüher M, Haviv YS, Stampfer MJ, Rudich A, Shai I.Changes of renal sinus fat and renal parenchymal fat during an 18-month randomized weight loss trial. Clin Nutr. 2017: S0261-5614(17)30146-2


Zieger K, Weiner J, Krause K, Schwarz M, Kohn M, Stumvoll MBlüher MHeiker JT. Vaspin suppresses cytokine-induced inflammation in 3T3-L1 adipocytes via inhibition of NFkB pathway. Mol Cell Endocrinol. 2017; Epub ahead of print.


Zieger K, Weiner J, Kunath A, Gericke M, Krause K, Kern M, Stumvoll MKlöting NBlüher MHeiker JT. Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high-fat diet induced obesity by counteracting adipose tissue inflammation in vivo. Cell Mol Life Sci. 2017; Epub ahead of print.

2016

Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM, Tragante V, van der Laan SW, Perry JR, Kong A; BIOS Consortium, Ahluwalia TS, Albrecht E, Yerges-Armstrong L, Atzmon G, Auro K, Ayers K, Bakshi A, Ben-Avraham D, Berger K, Bergman A, Bertram L, Bielak LF, Bjornsdottir G, Bonder MJ, Broer L, Bui M, Barbieri C, Cavadino A, Chavarro JE, Turman C, Concas MP, Cordell HJ, Davies G, Eibich P, Eriksson N, Esko T, Eriksson J, Falahi F, Felix JF, Fontana MA, Franke L, Gandin I, Gaskins AJ, Gieger C, Gunderson EP, Guo X, Hayward C, He C, Hofer E, Huang H, Joshi PK, Kanoni S, Karlsson R, Kiechl S, Kifley A, Kluttig A, Kraft P, Lagou V, Lecoeur C, Lahti J, Li-Gao R, Lind PA, Liu T, Makalic E, Mamasoula C, Matteson L, Mbarek H, McArdle PF, McMahon G, Meddens SF, Mihailov E, Miller M, Missmer SA, Monnereau C, van der Most PJ, Myhre R, Nalls MA, Nutile T, Kalafati IP, Porcu E, Prokopenko I, Rajan KB, Rich-Edwards J, Rietveld CA, Robino A, Rose LM, Rueedi R, Ryan KA, Saba Y, Schmidt D, Smith JA, Stolk L, Streeten E, Tönjes A, Thorleifsson G, Ulivi S, Wedenoja J, Wellmann J, Willeit P, Yao J, Yengo L, Zhao JH, Zhao W, Zhernakova DV, Amin N, Andrews H, Balkau B, Barzilai N, Bergmann S, Biino G, Bisgaard H, Bønnelykke K, Boomsma DI, Buring JE, Campbell H, Cappellani S, Ciullo M, Cox SR, Cucca F, Toniolo D, Davey-Smith G, Deary IJ, Dedoussis G, Deloukas P, van Duijn CM, de Geus EJ, Eriksson JG, Evans DA, Faul JD, Sala CF, Froguel P, Gasparini P, Girotto G, Grabe HJ, Greiser KH, Groenen PJ, de Haan HG, Haerting J, Harris TB, Heath AC, Heikkilä K, Hofman A, Homuth G, Holliday EG, Hopper J, Hyppönen E, Jacobsson B, Jaddoe VW, Johannesson M, Jugessur A, Kähönen M, Kajantie E, Kardia SL, Keavney B, Kolcic I, Koponen P, Kovacs P, Kronenberg F, Kutalik Z, La Bianca M, Lachance G, Iacono WG, Lai S, Lehtimäki T, Liewald DC; LifeLines Cohort Study, Lindgren CM, Liu Y, Luben R, Lucht M, Luoto R, Magnus P, Magnusson PK, Martin NG, McGue M, McQuillan R, Medland SE, Meisinger C, Mellström D, Metspalu A, Traglia M, Milani L, Mitchell P, Montgomery GW, Mook-Kanamori D, de Mutsert R, Nohr EA, Ohlsson C, Olsen J, Ong KK, Paternoster L, Pattie A, Penninx BW, Perola M, Peyser PA, Pirastu M, Polasek O, Power C, Kaprio J, Raffel LJ, Räikkönen K, Raitakari O, Ridker PM, Ring SM, Roll K, Rudan I, Ruggiero D, Rujescu D, Salomaa V, Schlessinger D, Schmidt H, Schmidt R, Schupf N, Smit J, Sorice R, Spector TD, Starr JM, Stöckl D, Strauch K, Stumvoll M, Swertz MA, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tung JY, Uitterlinden AG, Vaccargiu S, Viikari J, Vitart V, Völzke H, Vollenweider P, Vuckovic D, Waage J, Wagner GG, Wang JJ, Wareham NJ, Weir DR, Willemsen G, Willeit J, Wright AF, Zondervan KT, Stefansson K, Krueger RF, Lee JJ, Benjamin DJ, Cesarini D, Koellinger PD, den Hoed M, Snieder H, Mills MC. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nat Genet. 2016;48:1462-72.


Baum P, Kosacka J, Estrela-Lopis I, Woidt K, Serke H, Paeschke S, Stockinger M, Klöting NBlüher M, Dorn M, Classen J, Thiery JBechmann I, Toyka KV, Nowicki M. The role of nerve inflammation and exogenous iron load in experimental peripheral diabetic neuropathy (PDN). Metabolism. 2016;65:391-405.


Brune JE, Kern M, Kunath A, Flehmig G, Schön MR, Lohmann T, Dressler M, Dietrich A, Fasshauer MKovacs PStumvoll MBlüher MKlöting N. Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits. Obesity (Silver Spring). 2016;24:51-9.


Carmody RN, Dannemann M, Briggs AW, Nickel B, Groopmann EE, Wrangham RW, Kelso J. Genetic evidence of human adaption to a cooked diet. Genome Biol Evol. 2016;8:1091-103.


Dalgaard K, Landgraf K, Heyne S, Lempradi A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Tsai-Hsiu Lu T, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Loraine Tung YCL, Lam B, Larder R, Yeo GSH, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA. Trim28 haploinsufficiency triggers bi-stable epigenetic obesity. Cell. 2016;164:1-12.


Dannemann M, Andres AM, Kelso J. Introgression of Neandertal- and Denisovan-like haplotypes contributesto adaptive variation in human toll-like receptors. Am J Hum Genet. 2016;98:22-33.


Dietrich A, De Wit S, Horstmann A. General habit propensity relates to the sensation seeking subdomain of impulsivity but not obesity. Front Behav Neurosci. 2016;10:213.


Ebert T, Platz M, Kralisch S, Lossner U, Jessnitzer B, Richter J, Blüher MStumvoll MFasshauer M. Serum levels of copeptin are decreased in gestational diabetes mellitus. Exp Clin Endocrinol Diabetes. 2016;124:257-60.


Ehehalt S, Wiegand S, Körner A, Schweizer R, Liesenkötter KP, Partsch CJ, Blumenstock G, Spielau U, Denzer C, Ranke MB, Neu A, Binder G, Wabitsch M, Kiess W, Reinehr T. Low association between fasting and OGTT stimulated glucose levels with HbA1c in overweight children and adolescents. Pediatr Diabetes. 2016; Epub ahead of print.


Ehehalt S, Wiegand S, Körner A, Schweizer R, Liesenkötter KP, Partsch CJ, Blumenstock G, Spielau U, Denzer C, Ranke MB, Neu A, Binder G, Wabitsch M, Kiess W, Reinehr T. Low association between fasting and OGTT stimulated glucose levels with HbA1c in overweight children and adolescents. Pediatr Diabetes. 2016; Epub ahead of print.


Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, [47 authors], Kiess W, [14 authors], Pfäffle R, [33 authors], Körner A, [9 authors], Grant SF, Jaddoe VW, Early Growth Genetics C, Bone Mineral Density in Childhood Study BC. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet. 2016;25:389-403.


Fu Q, Posth C, Hajdinjak M, Petr M, Mallick S, Fernandes D, Furtwängler A, Haak W, Meyer M, Mittnik A, Nickel B, Peltzer A, Rohland N, Slon V, Talamo S, Lazaridis I, Lipson M, Mathieson I, Schiffels S, Skoglund P, Derevianko AP, Drozdov N, Slavinsky V, Tsybankov A, Cremonesi RG, Mallegni F, Gely B, Vacca E, Morales MR, Straus LG, Neugebauer-Maresch C, Teschler-Nicola M, Constantin S, Moldovan OT, Benazzi S, Peresani M, Coppola D, Lari M, Ricci S, Ronchitelli A, Valentin F, Thevenet C, Wehrberger K, Grigorescu D, Rougier H, Crevecoeur I, Flas D, Semal P, Mannino MA, Cupillard C, Bocherens H, Conard NJ, Harvati K, Moiseyev V, Drucker DG, Svoboda J, Richards MP, Caramelli D, Pinhasi R, Kelso J, Patterson N, Krause J, Pääbo S, Reich D. The genetic history of Ice Age Europe. Nature. 2016;534:200-5.


Garcia-Garcia I, Kube J, Gaebler M, Horstmann AVillringer ANeumann J. Neural processing of negative emotional stimuli and the influence of age, sex and task-related characteristics. Neurosci Biobehav Rev. 2016;68:773-93.


Gepner Y, Bril N, Shelef I, Schwarzfuchs D, Serfaty D, Rein M, Cohen N, Shemesh E, Tangi-Rosental O, Sarusi B, Goshen E, Kenigsbuch S1, Chassidim Y, Golan R, Witkow S, Henkin Y, Stampfer MJ, Rudich A, Shai I.Higher visceral adiposity is associated with an enhanced early thermogenic response to carbohydrate-rich food.Clin Nutr. 2016 Apr;35(2):422-427


Grellmann C, Neumann J, Bitzer S, Kovacs PTönjes A, Westlye LT, Anreassen OA, Stumvoll MVillringer AHorstmann A. Random projection for fast and efficient multivariate correlation analysis of high-dimensional data: A new approach. Front Genet. 2016;7:102.


Guiu-Jurado E, Unthan M, Böhler N, Kern M, Landgraf K, Dietrich A, Schleinitz D, Ruschke K, Klöting NFaßhauer MTönjes AStumvoll MKörner AKovacs PBlüher M. Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots. Obesity (Silver Spring). 2016;24:2092-100.


Hankir MK, Kranz M, Gnad T, Weiner J, Wagner S, Deuther-Conrad W, Bronisch F, Steinhoff K, Luthardt J, Klöting N, Hesse S, Seibyl JP, Sabri O, Heiker JTBlüher M, Pfeifer A, Brust P, Fenske WK. A novel thermoregulatory role for PDE10A in mouse and human adipocytes. EMBO Mol Med. 2016;8:796-812.


Hoffmann A, Manjowk GM, Wagner V, Klöting N, Ebert T, Jessnitzer B, Lössner U, Stukenborg JB, Blüher MStumvoll M, Söder O, Svechnikov K, Fasshauer M, Kralisch S. Leptin within the subphysiological to physiological range dose-dependently improves male reproductive function in an obesity mouse model. Endocrinology. 2016;157:2641-8.


Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikäinen LP, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga JJ, Vilor-Tejedor N, Joshi PK, Boh ET, Ntalla I, Pitkänen N, Mahajan A, van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RC, Tam CH, Tam WH; CHARGE Consortium Hematology Working Group, Ganesh SK, van Rooij FJ, Jones SE, Loh PR, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, van Beijsterveldt CE, Willemsen G, Appel EV, Fonvig CE, Trier C, Tiesler CM, Standl M, Kutalik Z, Bonàs-Guarch S, Hougaard DM, Sánchez F, Torrents D, Waage J, Hollegaard MV, de Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM; Early Growth Genetics (EGG) Consortium, Lowe WL, Tönjes AStumvoll M, Lindi V, Lakka TA, van Duijn CM, Kiess W, Körner A, Sørensen TI, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Melbye M, Campbell H, Wilson JF, Vrijheid M, de Geus EJ, Boomsma DI, Kadarmideen HN, Holm JC, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén E, Kähönen M, Viikari JS, Lehtimäki T, Vollenweider P, Bønnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hyppönen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VW, Järvelin MR, Grant SF, Vaag AA, Lawlor DA, Frayling TM, Smith GD, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JR, Evans DM, McCarthy MI, Freathy RM. Genome-wide associations for birth weight and correlations with adult disease. Nature. 2016;538:248-52.


Jendrny C, Beck-Sickinger AG. Inhibition of kallikrein-related peptidases 7 and 5 by grafting serpin reactive-center loop sequences onto sunflower trypsin inhibitor-1 (SFTI-1). Chembiochem. 2016;17:719-26.


Keller M, Hopp L, Liu X, Wohland T, Rohde K, Cancello R, Klös M, Bacos K, Kern M, Eichelmann F, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll MKovacs P, DiBlasio AM, Ling C, Binder H, Blüher M, Böttcher Y. Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity. Mol Metab. 2016;6:86-100.


Kharabian Masouleh S, Arelin K, Horstmann A, Lample L, Kipping JA, Luck T, Riedel-Heller SG, Schroeter ML, Stumvoll MVillringer A, Witte AV. Higher body mass index in older adults is associated with lower gray matter volume: implications for memory performance. Neurobiol Aging. 2016;40:1-10.


Köbe T, Witte AV, Schnelle A, Grittner U, Tesky VA, Pantel J, Schuchardt JP, Hahn A, Bohlken J, Rujescu D, Flöel A. Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment. Am J Clin Nutr. 2016;103:1045-54.


Köbe T, Witte AV, Schnelle A, Lesemann A, Fabian S, Tesky VA, Pantel J, Flöel A. Combined omega-3 fatty acids, aerobic exercise and cognitive stimulation prevents decline in gray matter volume of the frontal, parietal and cingulate cortex in patients with mild cognitive impairment. Neuroimage. 2016;131:226-38.


Kube J, Schrimpf A, Garcia-Garcia I, Villringer ANeumann JHorstmann A. Differential heart rate responses to social and monetary reinforcement in women with obesity. Psychophysiology. 2016;53:868-79.


Kumar S, Grundeis F, Brand C, Hwang HJ, Mehnert J, Pleger B. Differences in insula and pre-/frontal responses during reappraisal of food in lean and obese humans. Front Hum Neurosci. 2016;10:233.


Kunath A, Hesselbarth N, Gericke M, Kern M, Dommel S, Kovacs PStumvoll MBlüher MKlöting N. Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation. Biochem Biophys Res Commun. 2016;478:398-402.


Kunath A, Klöting N. Adipocyte biology and obesity-mediated adipose tissue remodeling. Obesity Medicine. 2016;4:15-20.

Landgraf K, Scholz M, Kovacs P, Kiess W, Körner A. FTO obesity risk variants are linked to adipocyte IRX3 expression and BMI of children - relevance of FTO variants to defend body weight in lean children? PLoS One. 2016;11:e0161739.


Lazaridis I, Nadel D, Rollefson G, Merrett DC, Rohland N, Mallick S, Fernandes D, Novac M, Gamarra B, Sirak K, Connell S, Stewardson K, Harney E, Fu Q, Gonzales-Fortes G, Jones ER, Roodenberg SA, Lengyel G, Bocquentin F, Gasparian B, Monge JM, Gregg M, Eshed V, Mizrahi AS, Meiklejohn C, Gerritsen F, Bejenaru L, Blüher M, Campbell A, Cavalleri G, Comas D, Froguel P, Gilbert E, Kerr SM, Kovacs P, Krause J, McGettigan D, Merrigan M, Merriwether DA, O'Reilly S, Richards MB, Semino O, Shamoon-Pour M, Stefanescu G, Stumvoll MTönjes A, Torroni A, Wilson JF, Yengo L, Hovhannisyan NA, Patterson N, Pinhasi R, Reich D. Genomic insights into the origin of farming in the ancient Near East. Nature. 2016;536:419-24.


Lede V, Franke C, Meusel A, Teupser D, Ricken A, Thiery JSchiller JHuster DSchöneberg TSchulz A. Severe atherosclerosis and hypercholesterolemia in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor. PLoS One. 2016;11:e0167888.


Löffler D, Behrendt S, Creemers JW, Klammt J, Aust G, Stanik J, Kiess W, Kovacs PKörner A. Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism. Mol Metab. 2016;6:295-305.


Mathar D, Horstmann APleger BVillringer ANeumann J. Is it worth the effort? Novel insights into obesity-associated alterations ins cost-benefit decision-making. Front Behav Neurosci. 2016;9:360.


Mathar D, Wilkinson L, Holl A, Neumann J, Deserno L, Villringer A, Jahanshahi M, Horstmann A. The role of dopamine in positive and negative prediction error utilization during incidental learning–insights from Positron Emission Tomography, Parkinson’s disease and Huntington’s disease. Cortex. 2016; Epub ahead of print.


Melasch J, Rullmann M, Hilbert A, Luthardt J, Becker GA, Patt M, Stumvoll MBlüher MVillringer A, Arelin K, Meyer PM, Bresch A, Sabri O, Hesse S, Pleger B. Sex differences in serotonin-hypothalamic connections underpin a diminished sense of emotional well-being with increasing body weight. Int J Obes (Lond). 2016;40:1268-77.


Melasch J, Rullmann M, Hilbert A, Luthardt J, Becker GA, Patt M, Villringer A, Arelin K, Meyer PM, Lobsien D, Ding Y-S, Müller K, Sabri O, Hesse S, Pleger B. The central nervours norepinephrine network links a diminished sense of emotional well-being to an increased body weight. Int J Obes. 2016;40:779-87.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Progranulin is increased in human and murine lipodystrophy. Diabetes Res Clin Pract. 2016;120:1-7.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Serum concentrations of fibroblast growth factor 21 are elevated in patients with congenital or acquired lipodystrophy. Cytokine. 2016;83:239-44.


Mühlberg C, Mathar D, Villringer AHorstmann ANeumann J. Stopping at the sight of food - How gender and obesity impact on response inhibition. Appetite. 2016;107:663-76.


Orthgiess J, Gericke M, Immig K, Schulz A, Hirrlinger J, Bechmann IEilers J. Neurons exhibit Lyz2 promotor activity in vivo: Implications for using LysM-Cre mice in myeloid cell research. Eur J Immunol. 2016;46:1529-32.


Pecht T, Haim Y, Bashan N, Shapiro H, Harman-Boehm I, Kirshtein B, Clement K, Shai I, Rudich A. Circulating blood monocyte subclasses and lipid-laden adipose tissue macrophages in human obesity. PLoS One. 2016;11:e0159350.


Pfeiffer S, Krüger J, Maierhofer A, Böttcher Y, Klöting N, El Hajj N, Schleinitz D, Schön MR, Dietrich A, Fasshauer M, Lohmann T, Dreßler M, Stumvoll M, Haaf T, Blüher MKovacs P. Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction. Sci Rep. 2016;6:27969.


Prasad RB, Lessmark A, Almgren P, Kovacs G, Hansson O, Oskolkov N, Vitai M, Ladenvall C, Kovacs P, Fadista J, Lachmann M, Zhou Y, Sonestedt E, Poon W, Wollheim CB, Orho-Melander M, Stumvoll M, Tuomi T, Pääbo S, Koranyi L, Groop L. Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes. Diabetologia. 2016;59:1702-13.


Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K, Kutalik Z, Lahti J, Luan J, Mägi R, Mahajan A, Mangino M, Medina-Gomez C, Monda KL, Nolte IM, Pérusse L, Prokopenko I, Qi L, Rose LM, Salvi E, Smith MT, Snieder H, Stančáková A, Ju Sung Y, Tachmazidou I, Teumer A, Thorleifsson G, van der Harst P, Walker RW, Wang SR, Wild SH, Willems SM, Wong A, Zhang W, Albrecht E, Couto Alves A, Bakker SJ, Barlassina C, Bartz TM, Beilby J, Bellis C, Bergman RN, Bergmann S, Blangero J, Blüher M, Boerwinkle E, Bonnycastle LL, Bornstein SR, Bruinenberg M, Campbell H, Chen YI, Chiang CW, Chines PS, Collins FS, Cucca F, Cupples LA, D'Avila F, de Geus EJ, Dedoussis G, Dimitriou M, Döring A, Eriksson JG, Farmaki AE, Farrall M, Ferreira T, Fischer K, Forouhi NG, Friedrich N, Gjesing AP, Glorioso N, Graff M, Grallert H, Grarup N, Gräßler J, Grewal J, Hamsten A, Harder MN, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Havulinna AS, Heliövaara M, Hillege H, Hofman A, Holmen O, Homuth G, Hottenga JJ, Hui J, Husemoen LL, Hysi PG, Isaacs A, Ittermann T, Jalilzadeh S, James AL, Jørgensen T, Jousilahti P, Jula A, Marie Justesen J, Justice AE, Kähönen M, Karaleftheri M, Tee Khaw K, Keinanen-Kiukaanniemi SM, Kinnunen L, Knekt PB, Koistinen HA, Kolcic I, Kooner IK, Koskinen S, Kovacs P, Kyriakou T, Laitinen T, Langenberg C, Lewin AM, Lichtner P, Lindgren CM, Lindström J, Linneberg A, Lorbeer R, Lorentzon M, Luben R, Lyssenko V, Männistö S, Manunta P, Leach IM, McArdle WL, Mcknight B, Mohlke KL, Mihailov E, Milani L, Mills R, Montasser ME, Morris AP, Müller G, Musk AW, Narisu N, Ong KK, Oostra BA, Osmond C, Palotie A, Pankow JS, Paternoster L, Penninx BW, Pichler I, Pilia MG, Polašek O, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rayner NW, Ribel-Madsen R, Rice TK, Richards M, Ridker PM, Rivadeneira F, Ryan KA, Sanna S, Sarzynski MA, Scholtens S, Scott RA, Sebert S, Southam L, Sparsø TH, Steinthorsdottir V, Stirrups K, Stolk RP, Strauch K, Stringham HM, Swertz MA, Swift AJ, Tönjes A, Tsafantakis E, van der Most PJ, Van Vliet-Ostaptchouk JV, Vandenput L, Vartiainen E, Venturini C, Verweij N, Viikari JS, Vitart V, Vohl MC, Vonk JM, Waeber G, Widén E, Willemsen G, Wilsgaard T, Winkler TW, Wright AF, Yerges-Armstrong LM, Hua Zhao J, Carola Zillikens M, Boomsma DI, Bouchard C, Chambers JC, Chasman DI, Cusi D, Gansevoort RT, Gieger C, Hansen T, Hicks AA, Hu F, Hveem K, Jarvelin MR, Kajantie E, Kooner JS, Kuh D, Kuusisto J, Laakso M, Lakka TA, Lehtimäki T, Metspalu A, Njølstad I, Ohlsson C, Oldehinkel AJ, Palmer LJ, Pedersen O, Perola M, Peters A, Psaty BM, Puolijoki H, Rauramaa R, Rudan I, Salomaa V, Schwarz PE, Shudiner AR, Smit JH, Sørensen TI, Spector TD, Stefansson K, Stumvoll M, Tremblay A, Tuomilehto J, Uitterlinden AG, Uusitupa M, Völker U, Vollenweider P, Wareham NJ, Watkins H, Wilson JF, Zeggini E, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, van Duijn CM, Fox C, Groop LC, Heid IM, Hunter DJ, Kaplan RC, McCarthy MI, North KE, O'Connell JR, Schlessinger D, Thorsteinsdottir U, Strachan DP, Frayling T, Hirschhorn JN, Müller-Nurasyid M, Loos RJ. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nat Commun. 2016;;7:13357.


Quach H, Rotival M, Pothlichet J, Loh YE, Dannemann M, Zidane N, Laval G, Patin E, Harmant C, Lopez M, Deschamps M, Naffakh N, Duffy D, Coen A, Leroux-Roels G, Clément F, Boland A, Deleuze JF, Kelso J, Albert ML, Quintana-Murci L. Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations. Cell. 2016;167:643-656.


Rockstroh D, Löffler D, Kiess W, Landgraf K, Körner A. Regulation of human adipogenesis by miR125b-5p. Adipocyte. 2016;5:283-97.


Saalbach A, Tremel J, Herbert D, Schwede K, Wandel E, Schirmer C, Anderegg U, Beck-Sickinger AGHeiker JT, Schultz S, Magin T, Simon JC. Anti-inflammatory action of keratinocyte-derived vaspin: relevance for the pathogenesis of psoriasis. Am J Pathol. 2016;186:639-51.


Schlögl H, Müller K, Horstmann A, Miehle K, Püschel J, Villringer APleger BStumvoll MFasshauer M. Leptin substitution in patients with lipodystrophy: Neural correlates for long-term success in the normalization of eating behavior. Diabetes. 2016;65:2179-86.


Schlögl H, Horstmann AVillringer AStumvoll M. Functional neuroimaging in obesity and the potential for development of novel treatments. Lancet Diabetes Endocrinol. 2016;4:695-705.


Schreier M, Schwartze JT, Landgraf K, Scheuermann K, Erbs S, Herberth G, Pospisilik JA, Kratzsch J, Kiess W, Körner A. Osteopontin is BMI-independently related to early endothelial dysfunction in children. J Clin Endocrinol Metab. 2016;101:4161-9.


Schröter J, Griesinger H, Reuß E, Schulz M, Riemer T, Süß R, Schiller J, Fuchs B. Unexpected products of the hypochlorous acid-induced oxidation of oleic acid: A study using high performance thin-layer chromatography-electrospray ionization mass spectrometry. J Chromatogr A. 2016;1439:89-96.


Schröter J, Schiller J. Chlorinated phospholipids and fatty acids: (patho)physiological relevance, potential toxicity, and analysis of lipid chlorohydrins. Oxid Med Cell Longev. 2016;2016:8386362.


Sjoerds Z, Dietrich A, Deserno L, de Wit S, Villringer A, Heinze HJ, Schlagenhauf F, Horstmann A. Slips of action and sequential decisions: A cross-validation study of tasks assessing habitual and goal-directed action control. Front Behav Neurosci. 2016;10:234.


Slutsky N, Vatarescu M, Haim Y, Goldstein N, Kirshtein B, Harman-Boehm I, Gepner Y, Shai I, Bashan N, Blüher MRudich A. Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity. Int J Obes (Lond). 2016;40:912-20.


Stelzner K, Herbert D, Popkova Y, Lorz A, Schiller JGericke MKlöting NBlüher M, Franz S, Simon JCSaalbach A. Free fatty acids sensitize dendritic cells to amplify TH1/TH17-immune responses. Eur J Immunol. 2016;46:2043-53.


Thieme V, Jolly N, Madsen AN, Bellmann-Sickert K, Schwartz TW, Holst B, Cox HM, Beck-Sickinger AG. High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice. Br J Pharmacol. 2016;173:3208-21.


Vausort M, Salgado-Somoza A, Zhang L, Leszek P, Scholz M, Teren A, Burkhardt RThiery J, Wagner DR, Devaux Y. Myocardial infarction-associated circular RNA predicting left ventricular dysfunction. J Am Coll Cardiol. 2016;68:1247-8.


Vernot B, Tucci S, Kelso J, Schraiber JG, Wolf AB, Gittelman RM, Dannemann M, Grote S, McCoy RC, Norton H, Scheinfeldt LB, Merriwether DA, Koki G, Friedlaender JS, Wakefield J, Pääbo S, Akey JM. Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals. Science. 2016;352:235-9.


Wagner IV, Klöting N, Atanassova N, Savchuk I, Spröte C, Kiess W, Söder O, Svechnikov K. Prepubertal onset of obesity negatively impacts on testicular steroidogenesis in rats. Mol Cell Endocrinol. 2016;437:154-62.

Weiner J, Kranz M, Klöting N, Kunath A, Steinhoff K, Rijntjes E, Köhrle J, Zeisig V, Hankir M, Gebhardt C, Deuther-Conrad W, Heiker JTFasshauer MStumvoll MBlüher M, Sabri O, Hesse S, Brust P, Tönjes A, Krause K. Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissue in mice. Sci Rep. 2016;6:38124.


Weingarten A, Turchetti L, Krohn K, Klöting I, Kern M, Kovacs PStumvoll MBlüher MKlöting N. Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size. Int J Obes (Lond). 2016;40:1832-40.


Welker F, Hajdinjak M, Talamo S, Jaouen K, Dannemann M, David F, Julien M, Meyer M, Kelso J, Barnes I, Brace S, Kamminga P, Fischer R, Kessler BM, Stewart JR, Pääbo S, Collins MJ, Hublin JJ. Palaeoproteomic evidence identifies archaic hominins associated with the Chatelperronian at the Grotte du Renne. Proc Natl Acad Sci U S A. 2016;113:11162-7.


Winkler TW, Justice AE, Graff M, [...], Blüher M, [...], Kovacs P, [...], Tönjes A, [...], Stumvoll M, [...], Loos RJ. Correction: The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study. PLoS Genet. 2016;12:e1006166.


Yaskolka Meir A, Shelef I, Schwarzfuchs D, Gepner Y, Tene L, Zelicha H, Tsaban G, Bilitzky A, Komy O, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Chassidim Y, Zeller L, Ceglarek U, Stumvoll M, Blüher M, Thiery J, Stampfer MJ, Rudich A, Shai I. Intermuscular adipose tissue and thigh muscle area dynamics during an 18-month randomized weight loss trial. J Appl Physiol (1985);121(2):518-27.

2015

Breitling C, Gross A, Büttner P, Weise S, Schleinitz D, Kiess W, Scholz M, Kovacs PKörner A. Genetic contribution of variants near SORT1 and APOE on LDL cholesterol independent of obesity in children. PLoS One. 2015;10:e0138064.


Burkhardt R, Kirsten H, Beutner F, Holdt LM, Gross A, Teren A, Tönjes A, Becker S, Krohn K, Kovacs PStumvoll M, Teupser D, Thiery J, Ceglarek U, Scholz M. Integration of genome-wide SNP data and gene-expression profiles reveals six novel loci and regulatory mechanisms for amino acids and acylcarnitines in whole blood. PLoS Genet. 2015;11:e1005510.


Deserno L, Wilbertz T, Reiter A, Horstmann ANeumann JVillringer A, Heinze HJ, Schlagenhauf F. Lateral prefrontal model-based signatures are reduced in individuals with high trait impulsivity. Transl Psychiatry. 2015;5:e659.


du Plessis J, van Pelt J, Korf H, Mathieu C, van der Schueren B, Lannoo M, Oyen T, Topal B, Fetter G, Nayler S, van der Merwe T, Windmolders P, van Gaal L, Verrijken A, Hubens G, Gericke M, Cassiman D, Francque S, Nevens F, van der Merwe S. Association of adipose tissue inflammation with histological severity of non-alcoholic fatty liver disease. Gastroenterology. 2015;149:635-48.


Garcia-Garcia I, Jurado MA, Garolera M, Marques-Iturria I, Horstmann A, Segura B, Pueyo R, Sender-Palacios MJ, Vernet-Vernet M, Villringer A, Junque C, Margulies DS, Neumann J. Functional network centrality in obesity: A resting-state and task fMRI study. Psychiatry Res. 2015;233:331-8.


Gericke M, Weyer U, Braune J, Bechmann IEilers J. A method for long-term live-imaging of tissue macrophages in adipose tissue explants. Am J Physiol Endocrinol Metab. 2015;308:E1023-33.


Grellmann C, Bitzer S, Neumann J, Westlye LT, Andreasseen OA, Villringer AHorstmann A. Comparison of variants of canonical correlation analysis and partial least squares for combined analysis of MRI and genetic data. Neuroimage. 2015;107C:289-310.


Garcia-Garcia I, , Jurado MA, Garolera M, Marques-Iturria I, Horstmann A, Segura B, Pueyo R, Sender-Palacios MJ, Vernet-Vernet M, Villringer A, Junque C, Margulies DS, Neumann J. Functional network centrality in obesity: A resting-state and task fMRI study. Psychiatry Res. 2015;233:3331-8.


Haim Y, Blüher M, Slutsky N, Goldstein N, Klöting N, Harman-Boehm I, Kirshstein B, Ginsberg D, Gericke M, Guiu Jurado E, Kovsan J, Tarnovscki T, Kachko L, Bashan N, Gepner Y, Shai I, Rudich A. Elevated autophagy gene expression in adipose tissue of humans: A potential non-cell-cycle-dependent function of E2F1. Autophagy. 2015;11:2074-88.


Hankir MK, Ashrafian H, Hesse S, Horstmann A, Fenske WK. Distinctive striatal dopamine signaling after dieting and gastric bypass. Trends Endocrinol Metab. 2015;26:223-30.

Hellrung L, Hollmann M, Zscheyge O, Schlumm T, Kalberlah C, Roggenhofer E, Okon-Singer H, Villringer AHorstmann A. Flexible adaptive paradigms for fMRI using a novel software package 'Brain Analysis in Real-Time' (BART). PLoS One. 2015;10:e0118890.


Hesselbarth N, Petinelli C, Gericke M, Berger C, Kunath A, Stumvoll MBlüher MKlöting N. Tamoxifen affects glucose and lipid metabolism parameters, causes browning of subcutaneous adipose tissue and transient body composition changes in C57BL/6NTac mice. Biochem Biophys Res Commun. 2015;464:724-9.


Horstmann A, Dietrich A, Mathar D, Pössel M, Villringer ANeumann J. Slave to habit? Obesity is associated with decreased behavioural sensitivity to reward devaluation. Appetite. 2015;87:175-83.


Horstmann A, Fenske WK, Hankir MK. Argument for a non-linear relationship between severity of human obesity and dopaminergic tone. Obes Rev. 2015;16:821-30.


Huhn S, Kharabian Masouleh S, Stumvoll MVillringer A, Witte V. Components of a Mediterranean diet and their impact on cognitive functions in aging. Front Aging Neurosci. 2015;7:132.


Kaiser A, Müller P, Zellmann T, Scheidt HA, Thomas L, Bosse M, Meier R, Meiler J, Huster DBeck-Sickinger AG, Schmidt P. Unwinding of the C-terminal residues of neuropeptide Y is critical for Y2 receptor binding and activation. Angew Chem Int Ed Engl. 2015;54:7446-9.


Kälin S, Heppner FL, Bechmann I, Prinz M, Tschöp MH, Yi CX. Hypothalamic innate immune reaction in obesity. Nat Rev Endocrinol. 2015;11:339-51.


Kannt A, Pfenniger A, Teichert L, Tönjes A, Dietrich A, Schön MR, Klöting NBlüher M. Association of nicotinamide-N-methyltransferase mRNA expression in human aidpose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. Diabetologia. 2015;58:799-808.


Kilian TM, Klöting N, Bergmann R, Els-Heindl S, Babilon S, Clement-Ziza M, Zhang Y, Beck-Sickinger AG, Chollet C. Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight. J Med Chem. 2015;58:4180-93.


Klöting N, Hesselbarth N, Gericke M, Kunath A, Biemann R, Chakaroun R, Kosacka J, Kovacs P, Kern M, Stumvoll M, Fischer B, Rolle-Kampczyk U, Feltens R, Otto W, Wissenbach DK, von Bergen M, BlüherM. Di-(2 Ehtylhexyl)-Phtalate (DEHP) causes impaired adipocyte function and alters serum metabolites. PLoS One. 2015;10:e0143190.


Knigge A, Klöting N, Schön MR, Dietrich A, Fasshauer M, Gärtner D, Lohmann T, Dreßler M, Stumvoll MKovacs PBlüher M. ADCY5 gene expression in adipose tissue is related to obesity in men and mice. PLoS One. 2015;10:e0120742.


Koch M, Varela L, Kim JG, Kim JD, Hernández-Nuño F, Simonds SE, Castorena CM, Vianna CR, Elmquist JK, Morozov YM, Rakic P, Bechmann I, Cowley MA, Szigeti-Buck K, Dietrich MO, Gao XB, Diano S, Horvath TL. Hypothalamic POMC neurons promote cannabinoid-induced feeding. Nature. 2015;519:45-50.


Kosacka J, Kern M, Klöting N, Paeschke S, Rudich A, Haim Y, Gericke M, Serke H, Stumvoll MBechmann I, Nowicki M, Blüher M. Autophagy in adipose tissue of patients with obesity and type 2 diabetes. Mol Cell Endocrinol. 2015;409:21-31.


Kralisch S, Klöting N, Ebert T, Kern M, Hoffmann A, Krause K, Jessnitzer B, Lossner U, Sommerer I, Stumvoll MFasshauer M. Circulating adipocyte fatty acid-binding protein induces insulin resistance in mice in vivo. Obesity (Silver Spring). 2015;23:1007-13.


Krause K, Weiner J, Hönes S, Klöting N, Rijntjes E, Heiker JT, Gebhardt C, Köhrle J, Führer D, Steinhoff K, Hesse S, Moeller LC, Tönjes A. The effects of thyroid hormones on gene expression of acyl-coenzyme A thioesterases in adipose tissue and liver of mice. Eur Thyroid J. 2015;4 (suppl 1):59-66.


Lakowa N, Trieu N, Flehmig G, Lohmann T, Schön MR, Dietrich A, Zeplin PH, Langer S, Stumvoll MBlüher MKlöting N. Telomere length differences between subcutaneous and visceral adipose tissue in humans. Biochem Biophys Res Commun. 2015;457:426-32.


Landgraf K, Rockstroh D, Wagner IV, Weise S, Tauscher R, Schwarze JT, Löffler D, Bühligen U, Wojan M, Till H, Kratzsch J, Kiess W, Blüher MKörner A. Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children. Diabetes. 2015;64:1249-61.


Löffler A, Luck T, Then FS, Luppa M, Sikorski C, Kovacs PTönjes A, Böttcher Y, Breitfeld J, Horstmann A, Löffler M, Engel C, Thiery JStumvoll M, Riedel-Heller SG. Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ). Appetite. 2015;91:241-7.


Löffler A, Luck T, Then FS, Sikorski C, Kovacs P, Böttcher Y, Breitfeld J, Tönjes AHorstmann A, Löffler M, Engel C, Thiery JVillringer AStumvoll M, Riedel-Heller SG. Eating behaviour in the general population: An analysis of the factor structure of the German version of the Three-Factor-Eating-Questionnaire (TFEQ) and its association with the body mass index. PLoS One. 2015;10:e0133977.


Löffler D, Müller U, Scheuermann K, Friebe D, Gesing J, Bielitz J, Erbs S, Landgraf K, Wagner IV, Kiess W, Körner A. Serum irisin levels are regulated by acute strenous exercise. J Clin Endocrinol Metab. 2015;100:1289-99.


Löffler D, Landgraf K, Körner A, Kratzsch J, Kirkby KC, Himmerich H. Modulation of triglyceride accumulation in adipocytes by psychopharmacological agents in vitro. J Psychiatr Res. 2015;72:37-42.


Mardinoglu A, Heiker JT, Gärtner D, Björnson E, Schön MR, Flehmig G, Klöting N, Krohn K, Fasshauer MStumvoll M, Nielsen J, Blüher M. Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue. Sci Rep. 2015;5:14841.


Mueller K, Möller HE, Horstmann A, Busse-Voigt FP, Lepsien J, Blüher MStumvoll MVillringer APleger B. Physical exercise in overweight to obese individuals induces metabolic- and neurotrophic-related structural brain plasticity. Front Hum Neurosci. 2015;9:372.


Park M, Sivertsen BB, Els-Heindl S, Huber T, Holst B, Beck-Sickinger AG, Schwartz TW, Sakmar TP. Bioorthogonal labeling of ghrelin receptor to facilitate studies of ligand-dependent conformational dynamics. Chem Biol. 2015;22:1431-6.


Pippel J, Küttner EB, Ulricht D, Daberger J, Schultz S, Heiker JTSträter N. Crystal structure of cleaved vaspin (serpinA12). Biol Chem. 2016;397:111-23.


Popkova Y, Meusel A, Breitfeld J, Schleinitz D, Hirrlinger J, Dannenberger D, Kovacs PSchiller J. Nutrition-dependent changes of mouse adipose tissue compositions monitored by NMR, MS, and chromatographic methods. Anal Bioanal Chem. 2015;407:5113-23.


Qi Q, Downer MK, Kilpelainen TO, Taal HR, Barton SJ, Ntalla I, Standl M, Boraska V, Huikari V, Kiefte-de Jong JC, Körner A, Lakka TA, Liu G, Magnusson J, Okuda M, Raitakari O, Richmond R, Scott RA, Bailey ME, Scheuermann K, Holloway JW, Inskip H, Isasi CR, Mossaar-Rahmani Y, Jaddoe VW, Laitinen J, Lindi V, Melen E, Pitsiladis Y, Pitkanen N, Snieder H, Heinrich J, Timpson NJ, Wang T, Yuji H, Zeggini E, Dedoussis GV, Kaplan RC, Wylie-Rosett J, Loos RJ, Hu FB, Qi L. Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes. 2015;64:2467-76

Rockstroh D, Landgraf K, Wagner IV, Gesing J, Tauscher R, Lakowa N, Kiess W, Bühligen U, Wojan M, Till H, Blüher MKörner A. Direct evidence of brown adipocytes in different fat depots in children. PLoS One. 2015;10:e0117841.


Rohde K, Keller M, Horstmann A, Liu X, Eichelmann F, Stumvoll MVillringer AKovacs PTönjes A, Böttcher Y. Role of genetic variants in ADIPOQ in human eating behavior. Genes Nutr. 2015;10:449.


Rohde K, Federbusch M, Horstmann A, Keller M, Villringer AStumvoll MTönjes AKovacs P, Böttcher Y. Genetic variants in AKR1B10 associate with human eating behavior. BMC Genet. 2015;16:31.


Ronke C, Dannemann M, Halbwax M, Fischer A, Helmschrodt C, Brügel M, André C, Atencia R, Mugisha L, Scholz M, Ceglarek U, Thiery J, Pääbo S, Prüfer K, Kelso J. Lineage-specific changes in biomarkers in great apes and humans. PLoS One. 2015;10:e0134548.


Schrey S, Wurst U, Ebert T, Kralisch S, Drewlo S, Stepan H, Lössner U, Platz M, Kratzsch J, Stumvoll MFasshauer M. The adipokine preadipocyte factor-1 is downregulated in preeclampsia and expressed in placenta. Cytokine. 2015;75:338-43.


Schunter JA, Löffler D, Wiesner T, Kovacs P, Badenhoop K, Aust G, Tönjes A, Müller P, Baber R, Simon JC, Führer D, Pfäffle RW, Thiery JStumvoll M, Kiess W, Kratzsch J, Körner A. A novel FoxD3 variant is associated with vitiligo and elevated thyroid auto-antibodies. J Clin Endocrinol Metab. 2015;100:E1335-42.


Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, [ ….],Kovacs P, [….], Zillikens MC, McCarthy MI, Speliotes EK, North KE, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJ, Cupples LA, Morris AP, Lindgren CM, Mohlke KL. New genetic loci link adipose and insulin biology to body fat di stribution. Nature. 2015;518:187-96.


Simmank J, Murawski C, Bode S, Horstmann A. Incidental rewarding cues influence economic decisions in people with obesity. Front Behav Neurosci. 2015;9:278.


Stenkamp-Strahm CM, Nyavor YE, Kappmeyer AJ, Horton S, Gericke M, Balemba OB. Prolonged high fat diet ingestion, obesity, and type 2 diabetes symptoms correlate with phenotypic plasticity in myenteric neurons and nerve damage in the mouse duodenum. Cell Tissue Res. 2015;361:411-26.


Ulbricht D, Pippel J, Schultz S, Meier R, Sträter NHeiker JT. A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin). Biochem J. 2015;470:357-67.


van der Valk RJ, Kreiner-Moller E, Kooijman MN, Guxens M, Stergiakouli E, Saaf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, [42 authors], Kiess W, Mahajan A, [45 authors], Sergeyev E, [14 authors], Bonnelykke K, Jaddoe VW. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet. 2015;24:1155-68.


Voisin S, Almen MS, Zheleznyakova GY, Lundberg L, Zarei S, Castillo S, Eriksson FE, Nilsson EK, Blüher M, Böttcher Y, Kovacs P, Klovins J, Rask-Andersen M, Schiöth HB. Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers. Genome Med. 2015;7:103.


Weiß CL, Dannemann M, Prüfer K, Burbano HA. Contesting the presence of wheat in the British Isles 8,000 years ago by assessing ancient DNA authenticity from low-coverage data. Elife. 2015;4.


Winkler TW, Justice AE, Graff M, [...], Blüher M, [...], Kovacs P, [...], Stumvoll M, [...], Loos RJ. The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study. PLoS One. 2015;11:e1005378.

2014

Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der meer P, Tanaka T, Wang F, Westra HJ, Franke L, Mihailov E, Milani L, Häldin J, Winkelmann J, Meitinger T, Thiery J, Peters A, Waldenberger M, Rendon A, Jolley J, Sambrook J, Kiemeney LA, Sweep FC, Sala CF, Schwienbacher C, Pichler I, Hui J, Demirkan A, Isaacs A, Amin N, Steri M, Waeber G, Verweij N, Powell JE, Nyholt DR, Heath AC, Madden PA, Visscher Uda M, Vollenweider P, Scott RA, Langenberg C, Wareham N; InterAct Consortium, van Dujin C, Beilgy J, Pramstaller PP, Hicks AA, Ouwehand WH, Oexle K, Gieger C, Metspalu A, Camaschella C, Toniolo D, Swinkels DW, Whitfield JB. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun. 2014;5:4926.


Berry R, Church CD, Gericke MT, Jeffery E, Colman L, Rodeheffer MS. Imaging of adipose tissue. Methods Enzymol. 2014;537:47-73


Blüher MKlöting N, Wueest S, Schoenle EJ, Schön MR, Dietrich A, Fasshauer MStumvoll M, Konrad D. Fas and FasL Expression in Human Adipose Tissue Is Related to Obesity, Insulin Resistance, and Type 2 Diabetes. J Clin Endocrinol Metab . 2014;99:E36-44.


Ceglarek U, Dittrich J, Helmschrodt C, Wagner K, Nofer JR, Thiery J, Becker S. Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry. Clin Chim Acta. 2014;435:1-6.


Cousminer DL, Stergiakouli E, Berry DJ, Ang W, Groen-Blokhuis MM, Körner A, Siitonen N, Ntalla I, Marinelli M, Perry JR, Kettunen J, Jansen R, Surakka I, Timpson NJ, Ring S, Mcmahon G, Power C, Wang C, Kähönen M, Viikari J, Lehtimäki T, Middeldorp CM, Hulshoff Pol HE, Neef M, Weise S, Pahkala K, Niinikoski H, Zeggini E, Panoutsopoulou K, Bustamante M, Penninx BW; ReproGen Consortium, Murabito J, Torrent M, Dedoussis GV, Kiess W, Boomsma DI, Pennell CE, Raitakari OT, Hyppönen E, Davey Smith G, Ripatti S, McCarthy MI, Widén E; Early Growth Genetics Consortium. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum Mol Genet. 2014;23:4452-64.


Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium, Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Leveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms. Cell. 2014;156:343-58.


Cottilard A, Poitou C, Torcivia A, Bouillot JL, Dietrich A, Klöting N, Gregoire C, Lolmede K, Blüher M, Clement K. Adipocyte size treshold matters: link with risk of type 2 diabetes and improved insulin resistance after gastric bypass. J Clin Endocrinol Metab. 2014;99:E1466-70.


Cousminer DL, Stergiakouli E, Berry DJ, Ang W, Groen-Blokhuis MM, Körner A, Siitonen N, Ntalla I, Marinelli M, Perry JR, Kettunen J, Jansen R, Surakka I, Timpson NJ, Ring S, McMahon G, Power C, Wang C, Kahonen M, Viikari J, Lehtimaki T, Mitteldorp CM, Hulshoff Pol HE, Neef M, Weise S, Pahkala K, Niinikoski H, Zeggini E, Panoutsopoulou K, Bustamante M, Penninx BW, Murabito J, Torrent M, Dedoussis GV, Kiess W, Boomsma DI, Pennell CE, Raitakari OT, Hypponen E, Davey SG, Ripatti S, McCarthy MI, Widen E. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum Mol Genet. 2014;23:4452-64.


Derikx MH, Kovacs P, Scholz M, Masson E, Chen JM, Ruffert C, Lichtner P, Te Morsche RH, Cavestro GM, Algül H, Berg T, Bödeker H, Blüher M, Bruno MJ, Buch S, Bugert P, Cichoz-Lach H, Dabrowski A, Farré A, Frank J, Gasiorowska A, Geisz A, Goni E, Grothaus J, Grützmann R, Haas S, Hampe J, Hellerbrand C, Hegyi P, Huster D, Ioana M, Iordache S, Jurkowska G, Keim V, Landt O, Di Leo M, Lerch MM, Lévy P, Löhr MJ, Macek M, Malats N, Malecka-Panas E, Mariani A, Martorana D, Mayerle J, Mora J, Mössner J, Müller S, Ockenga J, Paderova J, Pedrazzoli S, Pereira SP, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rohde K, Sack S, Saftoiu A, Schneider A, Schulz HU, Syoka M, Simon P, Skipworth J, Stickel F, Stumvoll M, Testoni PA, Tönjes A, Treiber M, Weiss FU, Werner J, Wodarz N, Férec C, Drenth JP, Witt H, Rosendahl J. Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut. 2014;64:1426-33.


Diaz Gimenez LE, Babilon S, Wanka L, Beck-Sickinger AG, Gurevich VV. Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes. Cell Signal. 2014;26:1523-31.


Dietrich A*, Federbusch MG*, Grellmann C, Villringer AHorstmann A. Body weight status, eating behavior, sensitivity to reward/punishment, and gender: relationships and interdependencies. Front Psychol. 2014;5:1073. *contributed equally.

Ebert T, Roth I, Richter J, Tönjes A, Kralisch S, Lossner U, Kratzsch J,Blüher MStumvoll MFasshauer M. Different associations of adipokines in lean and healthy adults.  Horm Metab Res. 2014;46:41-7


Ebert T, Stepan H, Schrey S, Kralisch S, Hindricks J, Hopf L, Platz M, Lossner U, Jessnitzer B, Drewlo S, Blüher MStumvoll M,Fasshauer M. Serum levels of irisin in gestational diabetes mellitus during pregnancy and after delivery. Cytokine. 2014;65:153-8.

Ebert T, Focke D, Petroff D, Wurst U, Richter J, Bachmann A, Lössner U, Kralisch S, Kratzsch J, Beige J, Bast I, Anders M, Blüher MStumvoll MFasshauer M. Serum levels of the myokine irisin in relation to metabolic and renal function. Eur J Endocrinol. 2014;170:501-6.


Ebert T, Hindricks J, Kralisch S, Lößner U, Jeßnitzer B, Richter J, Blüher MStumvoll MFasshauer M. Serum levels of fractalkine are associated with markers of insulin resistance in gestational diabetes mellitus. Diabetic Med. 2014;31:1014-7.


Ebert T, Kralisch S, Hoffmann A, Bachmann A, Lössner U, Kratzsch J, Blüher MStumvoll MTönjes AFaßhauer M. Circulation angiopoietin-like protein 8 is independently associated with fasting plasma glucose and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2014;99:E2510-7.


Eibisch M, Popkova Y, Süß R, Schiller J, Dannenberger D. Evaluation of a commercial enzymatic test kit regarding the quantitative analysis of different free fatty acids. Anal Bioanal Chem. 2014;406:7410-5.


Fasshauer MBlüher MStumvoll M. Adipokines in gestational diabetes. Lancet Diabetes Endocrinol. 2014;2:488-99.


Flehmig G, Scholz M, Klöting NFasshauer MTönjes AStumvoll M, Youn BS, Blüher M. Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation. PLoS One. 2014;9:e99785.


Garcia-Garcia I, Horstmann A, Jurado MA, Garolea M, Chaudhry SJ, Margulies DS, Villringer ANeumann J. Reward processing in obesity, substance addiction and non-substance addiction. Obes Rev. 2014;11:853-69.


Garnov N, Linder N, Schaudinn A, Blüher M, Karlas T, Schütz T, Dietrich A, Kahn T, Busse H. Comparison of T1 relaxation times in adipose tissue of severely obese patients and healthy lean subjects measured by 1.5 T MRI. NMR Biomed. 2014;27:1123-8.


Griesinger H, Fuchs B, Süß R, Matheis K, Schulz M, Schiller J. Stationary phase thickness determines the quality of thin-layer chromatography/matrix-assisted laser desorption and ionization mass spectra of lipids. Anal Biochem Chem. 2014;406:1291-306.


Haase J, Weyer U, Immig K, Klöting NBlüher MEilers JBechmann I, Gericke M. Local proliferation of macrophages in adipose tissue during obesity-induced inflammation.  Diabetologia. 2014;57:562-71.


Heiker JT*, Kunath A*, Kosacka J, Flehmig G, Knigge A, Kern M, Stumvoll MKovacs PBlüher MKlöting N. Identification of genetic loci associated with different responses to high fat died induced obesity (DIO) in C57BL/6N and C57BL/6J substrains. Physiol Genomics. 2014;46:377-84. (*contributed equally)

Heiker JT. Vaspin (serpinA12) in obesity, insulin resistance, and inflammation. J Pept Sci. 2014;20:299-306.


Helmschrodt C, Becker S, Thiery J, Ceglarek U. Preanalytical standardization for reactive oxygen species derived oxysterol analysis in human plasma by liquid chromatography-tandem mass spectrometry. Biochem Biophys Res Commun. 2014;446:726-30.


Hindricks J, Ebert T, Bachmann A, Kralisch S, Lössner U, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher MStumvoll MFasshauer M. Serum levels of fibroblast growth factor-21 are increased in chronic and acute renal dysfunction. Clin Endocrinol. 2014;80:918-24.


Jaskolla TW, Onischke K, Schiller J. 2,5-Dihydroxybenzoic acid salts for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric lipid analysis: Simplified spectra interpretation and insights into gasphase fragmentation. Rapid Commun Mass Spectrom. 2014;28:1353-63.


Keller M, Kralisch S, Rohde K, Schleinitz D, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Tönjes A, Stumvoll M, Kovacs P, Faßhauer M, Blüher M, Böttcher Y. Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis. Diabetologia. 2014;57:2374-83.


Kelso J, Prüfer K. Ancient humans and the origin of modern humans.Curr Opin Gen Dev. 2014;29:133-8.


Kern M, Kosacka J, Hesselbarth N, Brückner J, Heiker JT, Flehmig G, Klöting I, Kovacs P, Matz-Soja M, Gebhardt R, Krohn K, Sales S, Abshagen K, Shevchenko A, Stumvoll MBlüher MKlöting N. Liver-restricted Repin1 deficiency improves whole body insulin sensitivity, alters lipid metabolism and causes secondary changes in adipose tissue in mice. Diabetes. 2014;63:3295-309.


Khrameeva EE, Bozek K, He L, Yan Z, Jiang X, Wei Y, Tang K, Gelfand MS, Prufer K, Kelso J, Paabo S, Giavalisco P, Lachmann M, Khaitovich P. Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans. Nat Commun. 2014;5:3584.


Kralisch S, Ebert T, Lossner U, Jesnitzer B, Stumvoll MFasshauer M. Adipocyte fatty acid binding protein is released from adipocytes by a non-conventional mechanism. Int J Obes (Lond). 2014;38:1251-4.


Lo JC, Ljubicic S, Leibiger B, Kern M, Leibiger IB, Moede T, Kelly ME, Chatterjee Bhowmick D, Murano I, Cohen P, Banks AS, Khandekar MJ, Dietrich A, Flier JS, Cinti S, Blüher M, Danial NN, Berggren PO, Spiegelman BM. Adipsin is an adipokine that improves β cell function in diabetes. Cell. 2014;158:41-53.


Mäde V, Babilon S, Jolly N, Wanka L, Bellmann-Sickert K, Diaz Gimenez LE, Mörl K, Cox HM, Gurevich VV, Beck-Sickinger AG. Peptide modifications differentialy alter G protein-coupled receptor internalization and signaling bias. Angew Chem Int Ed. 2014;53:10067-71.


Mäde V, Els-Heindl S, Beck-Sickinger AG. Automated solid-phase peptide synthesis to obtain therapeutic peptides. Beilstein J Org Chem. 2014;10:1197-212.


Mangner N, Scheuermann K, Winzer E, Wagner I, Hoellriegel R, Sandri M, Zimmer M, Mende M, Linke A, Kiess W, Schuler G, Körner AErbs S. Childhood obesity: Impact on cardiac geometry and function. JACC Cardiovasc Imaging. 2014;7:1198-205.


Maric S, Skar-Gislinge N, Midtgaard S, Thygesen MB, Schiller J, Frielinghaus H, Moulin M, Haertlein M, Forsyth VT, Günther-Pomorski T, Arleth L. Stealtth carriers for low-resolution structure determination of membrance proteins in solution. Acta Cryst. 2014;70:317-28.


Mattern A, Zellmann T, Beck-Sickinger AG. Processing, signaling, and physiological function of chemerin. IUBMB Life. 2014;66:19-26.


Müller K*, Horstmann A*, Möller HE, Anwander A, Lepsien J, Schroeter ML, Villringer APleger B. Obesity associated cerebral gray and white matter alterations are interrelated in the female brain. PLoS One. 2014;9:e114206. (*contributed equally)

Nimptsch A, Pyttel S, Paasch U, Mohr C, Heinrich JM, Schiller J. A MALDI MS Investigation of the Lysophosphatidylcholine/Phosphatidylcholine Ratio in Human Spermatozoa and Erythrocytes as a Useful Fertility Marker. Lipids. 2014;49:287-93.


Pecht T, Gutman-Tirosh A, Bashan N, Rudich A. Peripheral blood leucocyte subclasses as potential biomarkers of adipose tissue inflammation and obesity subphenotypes in humans. Obes Rev. 2014;15:322-37.


Pedragosa-Badia X, Sliwoski GR, Dong Nguyen E, Lindner D, Stichel J, Kaufmann KW, Meiler J, Beck-Sickinger AG. Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket. J Biol Chem. 2014;289:5846-59.


Pirkl A, Meier M, Popkova Y, Letzel MC, Schnapp A, Schiller J, Dreisewerd K. Analysis of free fatty acids by ultraviolet laser desorption ionization mass spectrometry using insect wings as hydrophobic sample substrates. Anal Chem. 2014;86:10763-71.


Rohde K, Keller M, Klös M, Schleinitz D, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll MKovacs PBlüher M, Böttcher Y. Adipose tissue depot specific promotor methylation of TMEM18. J Mol Med. 2014;92:881-8.


Schleinitz D, Klöting N, Lindgren CM, Breitfeld J, Dietrich A, Schön MR, Lohmann T, Dreßler M, Stumvoll M, McCarthy MI, Blüher MKovacs P. Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio. Int J Obes (Lond). 2014;38:120-5.


Schleinitz D, Böttcher Y, Blüher MKovacs P. The genetics of fat distribution. Diabetologia. 2014;57:1276-86.


Stienstra R, Haim Y, Riahi Y, Netea M, Rudich A, Leibowitz G. Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes. Diabetologia. 2014;57:1505-16.


Stöckl D, Peters A, Thorand B, Heier M, Koenig W, Seissler J, Thiery J, Rathmann W, Meisinger C. Reproductive factors, intima media thickness and carotid plaques in a cross-sectional study of postmenopausal women enrolled in the population-based KORA F4 study. BMC Womens Health. 2014;14:17.


Tönjes A, Scholz M, Breitfeld J, Marzi C, Grallert H, Gross A, Ladenvall C, Schleinitz D, Krause K, Kirsten H, Laurila E, Kriebel J, Thorand B, Rathmann W, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Thiery JFasshauer MKlöting N, Gieger C, Blüher MStumvoll MKovacs P. Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genet. 2014;10:e1004854.


Wilbertz T, Deserno L, Horstmann ANeumann JVillringer A, Heinze HJ, Boehler CN, Schlagenhauf F. Response inhibition and its relation to multidimensional impulsivity. Neuroimage. 2014;103:241-8.


Zschörnig K, Schiller J. A simple method to generate oxidized phosphotidylcholines in amounts close to one milligram. Chem Phys Lipids. 2014;184:30-7.

2013

Gast MT, Tönjes A, Keller M, Horstmann A, Steinle N, Scholz M, Müller I, Villringer AStumvoll MKovacs P, Böttcher Y. The role of rs2237781 within GRM8 in eating behavior. Brain Behav. 2013;3:495-502.


Haim Y, Tarnovscki T, Bashari D, Rudich A. A chromatin immunoprecipitation (ChIP) protocol for use in whole human adipose tissue. Am J Physiol Endocrinol Metab. 2013;305:E1172-7.


Horstmann AKovacs P, Kabisch S, Boettcher Y, Schlögl H, Tönjes AStumvoll MPleger BVillringer A. Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior. PLoS One. 2013;8:e74362.


Heiker JT, Kern M, Kosacka J, Flehmig G, Stumvoll M, Shang E, Lohmann T, Dreßler M, Kovacs PBlüher MKlöting N. Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.  Obesity (Silver Spring). 2013;21:529-34.


Hoffmeister A, Tuennemann J, Sommerer I, Mössner J, Rittger A, Schleinitz D, Kratzsch J, Rosendahl J, Klöting N, Stahl T, Rossner S, Paroni F, Maedler K, Kovacs PBlüher M. Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression. Obesity (Silver Spring). 2013;21:E626-33.


Hollmann M, Pleger BVillringer AHorstmann A. Brain imaging in the context of food perception and eating. Curr Opin Lipidol. 2013;24:18-24. Review.


Keller M, Schleinitz D, Förster J, Tönjes A, Böttcher Y, Fischer-Rosinsky A, Breitfeld J, Weidle K, Rayner NW, Burkhardt R, Enigk B, Müller I, Halbritter J, Koriath M, Pfeiffer A, Krohn K, Groop L, Spranger J, Stumvoll MKovacs P. THOC5 : a novel gene involved in HDL-cholesterol metabolism. J Lipid Res. 2013;54:3170-6.


Keller M, Liu X, Wohland T, Rohde K, Gast MT, Stumvoll M, Kovacs PTönjes A, Böttcher Y. TAS2R38 and its influence on smoking behavior and glucose homeostasis in the German Sorbs. PLoS One. 2013;8:e80512.


Kosacka J, Koch K, Gericke M, Nowicki M, Heiker JT, Klöting I, Stumvoll MBlüher M, Klöting N. The polygenetically inherited metabolical syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue. Diabetol Metabol Syndr. 2013;5:23.


Kosacka J, Nowicki M, Blüher M, Baum P, Stockinger M, Toyka KV, Klöting I, Stumvoll M, Serke H, Bechmann IKlöting N. Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy. Exp Neurol. 2013;250:125-35.


Kovacs P, Miehle K, Sandner B, Stumvoll MBlüher M. Insulin administration acutely decreases vaspin serum concentrations in humans. Obes Facts. 2013;6:86-8.


Krist J, Wieder K, Klöting N, Oberbach A, Kralisch S, Wiesner T, Schön MR, Gärtner D, Dietrich A, Shang E, Lohmann T, Dreßler M, Fasshauer MStumvoll MBlüher M. Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity. Obes Facts. 2013;6:57-69.


Machann J, Horstmann A, Born M, Hesse S, Hirsch FW. Diagnostic imaging in obesity. Best Pract Res Clin Endocrinol Metab. 2013;27:261-77. Review.


Mai M, Tönjes AKovacs PStumvoll M, Fiedler GM, Leichtle AB. Serum levels of acylcarnitines are altered in prediabetic conditions. PLoS One. 2013;8:e82459.


Nimptsch A, Fuchs B, Süß R, Zschörnig K, Jakop U, Göritz F, Schiller J, Müller K. A simple method to identify ether lipids in spermatozoa samples by MALDI-TOF mass spectrometry. Anal Bioanal Chem. 2013;405:6675-82.


Scheidt HA, Meyer T, Nikolaus J, Baek DJ, Haralampiev I, Thomas L, Bittmann R, Müller P, Herrmann A, Huster D. Cholesterol's Aliphatic Side Chain Modulates Membrane Properties. Angew Chem Int Ed. 2013;52:12848–51.


Schlögl H*, Kabisch S*, Horstmann A, Lohmann G, Müller K, Lepsien J, Busse-Voigt F, Kratzsch J, Pleger BVillringer AStumvoll A. Exenatide-induced reduction in energy intake is associated with increase in hypothalamic connectivity. Diabetes Care. 2013;36:1933-40. (*contributed equally)

Blüher M, Klöting N, Schlich R, Willems M, Ruppe F, Knoefel WT, Dietrich A, Fielding BA, Arner P, Frayn KN, Eckel J. Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro. Diabetes Care. 2013;36:4083-90.


Steingroever H, Wetzels R, Horstmann ANeumann J, Wagenmakers EJ. Performance of healthy participants on the Iowa Gambling Task. Psychol Assess. 2013;25:180-93. Review.


Wegener J, Zschörnig K, Onischke K, Fuchs B, Schiller J, Müller K. Conservation of honey bee (Apis mellifera) sperm phospholipids during storage in the bee queen — A TLC/MALDI–TOF MS study. Exp Gero. 2013;48:213-22 .