Publications

Guidlines for Publication Funding

Guidelines for Publication Funding in the CRC1052

  • CRC has funds to support publication costs for scientific articles in peer-reviewed publications

  • The funds are allocated in Project Z2

  • Please note: correct reference to DFG funding is always necessary: 

    • „This work was funded by the German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) project number 209933838, CRC 1052/3, subproject ID“

  • Implementation of reimbursement of costs in prior coordination with Sandra Schulze

Central Department at Leipzig University

2024

Ackermann J, Arndt L, Fröba J, Lindhorst A, Glaß M, Kirstein M, Hobusch C, Wunderlich FT, Braune J, Gericke M. IL-6 signaling drives self-renewal and alternative activation of adipose tissue macrophages. Front Immunol. 2024 Feb 28;15:1201439.


Aldehoff AS, Karkossa I, Goerdeler C, Krieg L, Schor J, Engelmann B, Wabitsch M, Landgraf K, Hackermüller J, Körner A, Rolle-Kampczyk U, Schubert K, von Bergen M. Unveiling the dynamics of acetylation and phosphorylation in SGBS and 3T3-L1 adipogenesis. iScience. 2024 Apr 10;27(6):109711.


Brandt VP, Holland H, Blüher M, Klöting N. High-resolution genomic profiling and locus-specific FISH in subcutaneous and visceral adipose tissue of obese patients. Front Genet. 2024 Mar 7;14:1323052.


Boesch M, Lindhorst A, Feio-Azevedo R, Rescigno M, Gericke M, Korf H, van der Merwe S. Adipose tissue macrophage dysfunction is associated with a breach of vascular integrity in NASH. J Hepatol. 2023 Nov 15:S0168-8278(23)05271-6.


Czechowski P, Hagemann T, Ghosh A, Sun W, Dong H, Noé F, Niersmann C, Reinisch I, Wolfrum C, Herder C, Dietrich A, Blüher M, Hoffmann A. Expression of Intelectin-1, also known as Omentin-1, is related to clinical phenotypes such as overweight, obesity, insulin resistance, and changes after bariatric surgery. Sci Rep. 2024 Sep 27;14(1):22286.


Dietzsch AN, Al-Hasani H, Altschmied J, Bottermann K, Brendler J, Haendeler J, Horn S, Kaczmarek I, Körner A, Krause K, Landgraf K, Le Duc D, Lehmann L, Lehr S, Pick S, Ricken A, Schnorr R, Schulz A, Strnadová M, Velluva A, Zabri H, Schöneberg T, Thor D, Prömel S. Dysfunction of the adhesion G protein-coupled receptor latrophilin 1 (ADGRL1/LPHN1) increases the risk of obesity. Signal Transduct Target Ther. 2024 Apr 26;9(1):103.


Finkelstein O, Levakov G, Kaplan A, Zelicha H, Meir AY, Rinott E, Tsaban G, Witte AV, Blüher M, Stumvoll M, Shelef I, Shai I, Riklin Raviv T, Avidan G. Deep learning-based BMI inference from structural brain MRI reflects brain alterations following lifestyle intervention. Hum Brain Mapp. 2024 Feb 15;45(3):e26595.


Goldberg DT, Yaskolka Meir A, Tsaban G, Rinott E, Kaplan A, Zelicha H, Klöting N, Ceglarek U, Iserman B, Shelef I, Rosen P, Blüher M, Stumvoll M, Etzion O, Stampfer MJ, Hu FB, Shai I. Novel proteomic signatures may indicate MRI-assessed intrahepatic fat state and changes; the DIRECT PLUS clinical trial. Hepatology. 2024 Mar 27.


Hernandez-Resendiz I, Burkhardt R. Novel functions of Tribbles-homolog 1 in liver, adipocytes and atherosclerosis. Curr Opin Lipidol. 2024 Jan 18.


Kneuer JM, Grajek IA, Winkler M, Erbe S, Meinecke T, Weiss R, Garfias-Veitl T, Sheikh BN, König AC, Möbius-Winkler MN, Kogel A, Kresoja KP, Rosch S, Kokot KE, Filipova V, Gaul S, Thiele H, Lurz P, von Haehling S, Speer T, Laufs U, Boeckel JN. Novel Long Noncoding RNA HEAT4 Affects Monocyte Subtypes, Reducing Inflammation and Promoting Vascular Healing. Circulation. 2024 Jul 15.


Krupka S, Hoffmann A, Jasaszwili M, Dietrich A, Guiu-Jurado E, Klöting N, Blüher M. Consequences of COVID-19 on Adipose Tissue Signatures. Int J Mol Sci. 2024 Mar 2;25(5):2908.


Lorenz J, Richter S, Kirstein AS, Kolbig F, Nebe M, Schulze M, Kiess W, Spitzbarth I, Klöting N, Le Duc D, Baschant U, Garten A. Pten knockout in mouse preosteoblasts leads to changes in bone turnover and strength. JBMR Plus. 2024 Jan 4;8(3):ziad016.


Makarenkov N, Yoel U, Haim Y, Pincu Y, Bhandarkar NS, Shalev A, Shelef I, Liberty IF, Ben-Arie G, Yardeni D, Rudich A, Etzion O, Veksler-Lublinsky I. Circulating isomiRs May Be Superior Biomarkers Compared to Their Corresponding miRNAs: A Pilot Biomarker Study of Using isomiR-Ome to Detect Coronary Calcium-Based Cardiovascular Risk in Patients with NAFLD. Int J Mol Sci. 2024 Jan 10;25(2):890.


Moth CW, Sheehan JH, Mamun AA, Sivley RM, Gulsevin A, Rinker D, Capra JA, Meiler J. VUStruct: a compute pipeline for high throughput and personalized structural biology. bioRxiv [Preprint]. 2024 Aug 7:2024.08.06.606224.


Müller L, Hoffmann A, Bernhart SH, Ghosh A, Zhong J, Hagemann T, Sun W, Dong H, Noé F, Wolfrum C, Dietrich A, Stumvoll M, Massier L, Blüher M, Kovacs P, Chakaroun R, Keller M. Blood methylation pattern reflects epigenetic remodelling in adipose tissue after bariatric surgery. EBioMedicine. 2024 Jul 12;106:105242.


Pachter D, Kaplan A, Tsaban G, Zelicha H, Meir AY, Rinott E, Levakov G, Salti M, Yovell Y, Huhn S, Beyer F, Witte V, Kovacs P, von Bergen M, Ceglarek U, Blüher M, Stumvoll M, Hu FB, Stampfer MJ, Friedman A, Shelef I, Avidan G, Shai I. Glycemic Control Contributes to the Neuroprotective Effects of Mediterranean and Green-Mediterranean Diets on Brain Age; The DIRECT PLUS Brain-MRI Randomized Controlled Trial. Am J Clin Nutr. 2024 Sep 14:S0002-9165(24)00745-7.


Philipp M, Moth CW, Ristic N, Tiemann JKS, Seufert F, Panfilova A, Meiler J, Hildebrand PW, Stein A, Wiegreffe D, Staritzbichler R. MutationExplorer: a webserver for mutation of proteins and 3D visualization of energetic impacts. Nucleic Acids Res. 2024 Apr 22:gkae301.


Pott J, Kheirkhah A, Gadin JR, Kleber ME, Delgado GE, Kirsten H, Forer L, Hauck SM, Burkhardt R, Scharnagl H, Loeffler M, März W, Thiery J, Gieger C, Peters A, Silveira A, Hooft FV, Kronenberg F, Scholz M. Sex and statin-related genetic associations at the PCSK9 gene locus: results of genome-wide association meta-analysis. Biol Sex Differ. 2024 Mar 26;15(1):26.


Rauscher FG, Elze T, Francke M, Martinez-Perez ME, Li Y, Wirkner K, Tönjes A, Engel C, Thiery J, Blüher M, Stumvoll M, Kirsten T, Loeffler M, Ebert T, Wang M. Glucose tolerance and insulin resistance/sensitivity associate with retinal layer characteristics: the LIFE-Adult-Study. Diabetologia. 2024 Mar 2.


Reinisch I, Michenthaler H, Sulaj A, Moyschewitz E, Krstic J, Galhuber M, Xu R, Riahi Z, Wang T, Vujic N, Amor M, Zenezini Chiozzi R, Wabitsch M, Kolb D, Georgiadi A, Glawitsch L, Heitzer E, Schulz TJ, Schupp M, Sun W, Dong H, Ghosh A, Hoffmann A, Kratky D, Hinte LC, von Meyenn F, Heck AJR, Blüher M, Herzig S, Wolfrum C, Prokesch A. Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape. Nat Commun. 2024 Feb 15;15(1):1391.


Röthe J, Kraft R, Ricken A, Kaczmarek I, Matz-Soja M, Winter K, Dietzsch AN, Buchold J, Ludwig MG, Liebscher I, Schöneberg T, Thor D. The adhesion GPCR GPR116/ADGRF5 has a dual function in pancreatic islets regulating somatostatin release and islet development. Commun Biol. 2024 Jan 16;7(1):104.   


Schenk M, König N, Hey-Hawkins E, Beck-Sickinger AG. Illuminating the Path to Enhanced Bioimaging by Phosphole-based Fluorophores. Chembiochem. 2024 Jan 11.


Schenk M, Mörl K, Herzig S, Beck-Sickinger AG. Targeted modulation of gene expression through receptor-specific delivery of small interfering RNA peptide conjugates. J Pept Sci. 2024 May 7:e3611.


Scholz M, Horn K, Pott J, Wuttke M, Kühnapfel A, ..., Isermann B, ... Kiess W, ..., Körner A, Kovacs P, ... Stumvoll M,... Tönjes A, .... X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements. Nat Commun. 2024 Jan 18;15(1):586.


Schöneberg T. Modulating Vertebrate Physiology by Genomic Fine-Tuning of GPCR Functions. Physiol Rev. 2024 Jul 25.


Smith ST, Cassada JB, Von Bredow L, Erreger K, Webb EM, Trombley TA, Kalbfleisch JJ, Bender BJ, Zagol-Ikapitte I, Kramlinger VM, Bouchard JL, Mitchell SG, Tretbar M, Shoichet BK, Lindsley CW, Meiler J, Hamm HE. Discovery of Protease-Activated Receptor 4 (PAR4)-Tethered Ligand Antagonists Using Ultralarge Virtual Screening. ACS Pharmacol Transl Sci. 2024 Mar 21;7(4):1086-1100.


Sorek G, Haim Y, Chalifa-Caspi V, Lazarescu O, Ziv-Agam M, Hagemann T, Nono Nankam PA, Blüher M, Liberty IF, Dukhno O, Kukeev I, Yeger-Lotem E, Rudich A, Levin L. sNucConv: A bulk RNA-seq deconvolution method trained on single-nucleus RNA-seq data to estimate cell-type composition of human adipose tissues. iScience. 2024 Jun 24;27(7):110368.


Stassart RM, Gomez-Sanchez JA, Lloyd AC. Targeting ion channels with ultra-large library screening for hit discovery. Front Mol Neurosci. 2024 Jan 5;16:1336004.


Useini A, Schwerin IK, Künze G, Sträter N. Structural Studies on the Binding Mode of Bisphenols to PPARγ. Biomolecules. 2024 May 30;14(6):640.


Vallat B, Webb BM, Westbrook JD, Goddard TD, Hanke CA, Graziadei A, Peisach E, Zalevsky A, Sagendorf J, Tangmunarunkit H, Voinea S, Sekharan M, Yu J, A M J J Bonvin A, DiMaio F, Hummer G, Meiler J, Tajkhorshid E, Ferrin TE, Lawson CL, Leitner A, Rappsilber J, Seidel CAM, Jeffries CM, Burley SK, Hoch JC, Kurisu G, Morris K, Patwardhan A, Velankar S, Schwede T, Trewhella J, Kesselman C, Berman HM, Sali A. IHMCIF: An Extension of the PDBx/mmCIF Data Standard for Integrative Structure Determination Methods. J Mol Biol. 2024 Mar 18:168546.


2023

Abdul Majeed S, Dunzendorfer H, Weiner J, Heiker J T, Kiess W, Körner A, Landgraf K. COBL, MKX and MYOC Are Potential Regulators of Brown Adipose Tissue Development Associated with Obesity-Related Metabolic Dysfunction in Children. International Journal of Molecular Sciences 24, no. 4: 3085.


Arndt L, Hernandez-Resendiz I, Moos D, Dokas J, Müller S, Jeromin F, Wagner R, Ceglarek U, Heid IM, Höring M, Liebisch G, Stadler SC, Burkhardt R. Trib1 Deficiency Promotes Hyperlipidemia, Inflammation, and Atherosclerosis in LDL Receptor Knockout Mice. Arterioscler Thromb Vasc Biol. 2023 Jun;43(6):979-994.


Arndt L, Lindhorst A, Neugebauer J, Hoffmann A, Hobusch C, Alexaki VI, Ghosh A, Blüher M, Wolfrum C, Glaß M, Gericke M. The Role of IL-13 and IL-4 in Adipose Tissue Fibrosis. Int J Mol Sci. 2023 Mar 16;24(6):5672.


Avila Castillo A, Hagemann T, Hoffmann A, Baber R, Biemann R, Wirkner K, Krupka S, Stumvoll M, Blüher M, Klöting N. Associations between vitamin D, immunoglobulin E concentrations, and obesity. Front Nutr. 2023 Mar 30;10:1147407.


Baalmann F, Brendler J, Butthof A, Popkova Y, Engel KM, Schiller J, Winter K, Lede V, Ricken A, Schöneberg T, Schulz A. Reduced urine volume and changed renal sphingolipid metabolism in P2ry14-deficient mice. Front Cell Dev Biol. 2023 May 11;11:1128456.


Begcevic Brkovic I, Reinicke M, Chey S, Bechmann I, Ceglarek U. Characterization of Non-Cholesterol Sterols in Microglia Cell Membranes Using Targeted Mass Spectrometry. Cells. 2023 Mar 23;12(7):974.


Beuchel C, Dittrich J, Becker S, Kirsten H, Tönjes A, Kovacs P, Stumvoll M, Loeffler M, Teren A, Thiery J, Isermann B, Ceglarek U, Scholz M. An atlas of genome-wide gene expression and metabolite associations and possible mediation effects towards body mass index. J Mol Med (Berl). 2023 Sep 6.


Breitfeld J, Horn K, Le Duc D, Velluva A, Marzi C, Grallert H, Friedrich N, Pietzner M, Völker U, Völzke H, Ahlqvist E, Aly DM, Tuomi T, Baber R, Kratzsch J, Thiery J, Isermann B, Loeffler M, Klöting N, Blüher M, Stumvoll M, Heiker JT, Tönjes A, Scholz M, Kovacs P. Genetic dissection of serum vaspin highlights its causal role in lipid metabolism. Obesity (Silver Spring). 2023 Sep 26.  


Boczki P, Colombo M, Weiner J, Rapöhn I, Lacher M, Kiess W, Hanschkow M, Körner A, Landgraf K. Inhibition of AHCY impedes proliferation and differentiation of mouse and human adipocyte progenitor cells. Adipocyte. 2024 Dec;13(1):2290218.


Bundalian L, Su YY, Chen S, Velluva A, Kirstein AS, Garten A, Biskup S, Battke F, Lal D, Heyne HO, Platzer K, Lin CC, Lemke JR, Le Duc D. Epi25 Collaborative. The role of rare genetic variants enrichment in epilepsies of presumed genetic etiology. medRxiv [Preprint]. 2023 Mar 10:2023.01.17.23284702.


Ebert T, Behre G, Weidhase L, Vucinic V, Gewert C, Semple RK, Stumvoll M, Tönjes A. Case report: Allogeneic stem cell transplantation for type B insulin resistance. Front Med (Lausanne). 2023 Aug 29;10:1200037.


Emonds JJ, Arlt F, Gaudl A, Reinicke M, Heinemann M, Lindner D, Laudi S, Ceglarek U, Meixensberger J. Trimethylamine N-oxide (TMAO) in patients with subarachnoid hemorrhage: a prospective observational study. Acta Neurochir (Wien). 2023 Jan 25.


Frenster JD, Erdjument-Bromage H, Stephan G, Ravn-Boess N, Wang S, Liu W, Bready D, Wilcox J, Kieslich B, Jankovic M, Wilde C, Horn S, Sträter N, Liebscher I, Schöneberg T, Fenyo D, Neubert TA, Placantonakis DG. PTK7 is a positive allosteric modulator of GPR133 signaling in glioblastoma. Cell Rep. 2023 Jun 23;42(7):112679.


Hagemann T, Czechowski P, Ghosh A, Sun W, Dong H, Noé F, Wolfrum C, Blüher M, Hoffmann A. Laminin α4 Expression in Human Adipose Tissue Depots and Its Association with Obesity and Obesity Related Traits. Biomedicines. 2023 Oct 17;11(10):2806.


Hammel MC, Stein R, Kratzsch J, Vogel M, Eckert AJ, Triatin RD, Colombo M, Meigen C, Baber R, Stanik J, Spielau U, Stoltze A, Wirkner K, Tönjes A, Snieder H, Holl RW, Stumvoll M, Blüher M, Kiess W, Körner A. Fasting indices of glucose-insulin-metabolism across life span and prediction of glycemic deterioration in children with obesity from new diagnostic cut-offs. Lancet Reg Health Eur. 2023 May 23;30:100652. eCollection 2023 Jul.


Hartmann H, Janssen L K, Herzog N, Morys F, Fängström D, Fallon S J, Horstmann A., Self-reported intake of high-fat and high-sugar diet is not associated with cognitive stability and flexibility in healthy men. Appetite. 2023 Feb 8;183:106477. 


Henschke V, Hild K, Schilling E, Haas J, Filipova V, Erbe S, König R, Hübschen JM, Laufs U, Claus C, Boeckel JN. Rubella virus infection in endothelial cells reduces angiogenesis via interferon beta-induced CXCL10. iScience. 2023 Mar 7;26(4):106352.


Hoffmann A, Meir AY, Hagemann T, Czechowski P, Müller L, Engelmann B, Haange SB, Rolle-Kampczyk U, Tsaban G, Zelicha H, Rinott E, Kaplan A, Shelef I, Stumvoll M, Blüher M, Liang L, Ceglarek U, Isermann B, von Bergen M, Kovacs P, Keller M, Shai I. A polyphenol-rich green Mediterranean diet enhances epigenetic regulatory potential: the DIRECT PLUS randomized controlled trial. Metabolism. 2023 May 24:155594.


Kabbani N, Blüher M, Stepan H, Stumvoll M, Ebert T, Tönjes A, Schrey-Petersen S. Adipokines in Pregnancy: A Systematic Review of Clinical Data. Biomedicines. 2023 May 11;11(5):1419.


Kabbani N, Stepan H, Blüher M, Ebert T, Baber R, Vogel M, Kiess W, Stumvoll M, Breitfeld J, Lössner U, Tönjes A, Schrey-Petersen S. Association between TGFβ1 Levels in Cord Blood and Weight Progress in the First Year of Life. Biomedicines. 2023 Aug 8;11(8):2220.


Kaczmarek I, Wower I, Ettig K, Kuhn CK, Kraft R, Landgraf K, Körner A, Schöneberg T, Horn S, Thor D. Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS. iScience. 2023 Sep 9;26(10):107841.


Kamer O, Rinott E, Tsaban G, Kaplan A, Yaskolka Meir A, Zelicha H, Knights D, Tuohy K, Fava F, Uwe Scholz M, Ziv O, Rubin E, Blüher M, Stumvoll M, Ceglarek U, Clément K, Koren O, Hu FB, Stampfer MJ, Wang DD, Youngster I, Shai I. Successful weight regain attenuation by autologous fecal microbiota transplantation is associated with non-core gut microbiota changes during weight loss; randomized controlled trial. Gut Microbes. 2023 Dec;15(2):2264457.


Lammer L, Beyer F, Luppa M, Sanders C, Baber R, Engel C, Wirkner K, Loffler M, Riedel-Heller SG, Villringer A, Witte AV. Impact of social isolation on grey matter structure and cognitive functions: A population-based longitudinal neuroimaging study. Elife. 2023 Jun 20;12:e83660.


Lammert M, Medawar E, Hartmann H, Grasser L, Dietrich A, Fenske W, Horstmann A. Distinct adaptations of endocrine and cognitive functions may contribute to high variability in long-term weight loss outcome after bariatric surgery. Physiol Behav. 2023 Jun 23:114279.


Leopold J, Prabutzki P, Engel KM, Schiller J. A Five-Year Update on Matrix Compounds for MALDI-MS Analysis of Lipids. Biomolecules. 2023; 13(3):546.


Levakov G, Kaplan A, Yaskolka Meir A, Rinott E, Tsaban G, Zelicha H, Blüher M, Ceglarek U, Stumvoll M, Shelef I, Avidan G, Shai I. The effect of weight loss following 18 months of lifestyle intervention on brain age assessed with resting-state functional connectivity. Elife. 2023 Apr 6;12:e83604.


Liessmann F, Künze G, Meiler J. Improving the Modeling of Extracellular Ligand Binding Pockets in RosettaGPCR for Conformational Selection. Int J Mol Sci. 2023 Apr 24;24(9):7788.


Makarenkov N, Haim Y, Yoel U, Pincu Y, Tarnovscki T, Liberty IF, Kukeev I, Baraf L, Dukhno O, Zilber O, Blüher M, Rudich A, Veksler-Lublinsky I. Circulating miRNAs detect high versus low visceral adipose tissue inflammation in patients living with obesity. J Clin Endocrinol Metab. 2023 Sep 15:dgad550.


Medawar E, Beyer F, Thieleking R, Haange SB, Rolle-Kampczyk U, Reinicke M, Chakaroun R, von Bergen M, Stumvoll M, Villringer A, Witte AV. Prebiotic diet changes neural correlates of food decision-making in overweight adults: a randomised controlled within-subject cross-over trial. Gut. 2023 Oct 4:gutjnl-2023-330365.


Meen AJ, Doncheva AI, Böttcher Y, Dankel SN, Hoffmann A, Blüher M, Fernø J, Mellgren G, Ghosh A, Sun W, Dong H, Noé F, Wolfrum C, Pejler G, Dalen KT, Kolset SO. Obesity Is Associated with Distorted Proteoglycan Expression in Adipose Tissue. Int J Mol Sci. 2023 Apr 7;24(8):6884.


Molder J, Guiu-Jurado E, Moulla Y, Stroh C, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dressler M, Stumvoll M, Kovacs P, Blüher M, Klöting N., Sex-Specific Effects of the Genetic Variant rs10487505 Upstream of leptin in the Development of Obesity. Genes. 2023; 14(2):378.  


Mueller K, Thiel F, Taskin B, Beutner F, Teren A, Dubovoy VK, Möller HE, Villringer A, Schroeter ML. Brain dysconnectivity with heart failure. Brain Commun. 2023 Mar 30;5(2):fcad103.


Ott R, Stein R, Hauta-Alus HH, Ronkainen J, Fernández-Barrés S, Spielau U, Kirsten H, Poulain T, Melton PE, Küpers LK, Azaryah H, Colombo M, Landgraf K, Tobi EW, O'Sullivan T, Huang RC, Campoy C, Winkler C, Vioque J, Vrijheid M, Kiess W, Körner A, Sebert S, Jarvelin MR, Ziegler AG, Hummel S. Epigenome-Wide Meta-Analysis Reveals Associations Between Dietary Glycemic Index and Glycemic Load and DNA Methylation in Children and Adolescents of Different Body Sizes. Diabetes Care. 2023 Sep 26:dc230474.


Pincu Y, Makarenkov N, Tsitrina AA, Rosengarten-Levine M, Haim Y, Yoel U, Liberty IF, Dukhno O, Kukeev I, Blüher M, Veksler-Lublinsky I, Rudich A. Visceral adipocyte size links obesity with dysmetabolism more than fibrosis, and both can be estimated by circulating miRNAs. Obesity (Silver Spring). 2023 Sep 25.  


Rajcsanyi LS, Hoffmann A, Ghosh A, Matrisch-Dinkler B, Zheng Y, Peters T, Sun W, Dong H, Noé F, Wolfrum C, Herpertz-Dahlmann B, Seitz J, de Zwaan M, Herzog W, Ehrlich S, Zipfel S, Giel K, Egberts K, Burghardt R, Föcker M, Tsai LT, Müller TD, Blüher M, Hebebrand J, Hirtz R, Hinney A. Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa. Front Genet. 2023 Apr 10;14:1128133.


Rapöhn I, Elias I, Weiner J, Pujol A, Kehr S, Chadt A, Al-Hasani H, Burkhardt R, Klöting N, Stumvoll M, Bosch F, Kovacs P, Heiker JT, Breitfeld J. Overexpressing high levels of human vaspin limits high fat diet-induced obesity and enhances energy expenditure in a transgenic mouse. Front Endocrinol (Lausanne). 2023 Apr 19;14:1146454.


Roth L, Johann K, Hönes GS, Oelkrug R, Wagner L, Hoffmann A, Krohn K, Moeller LC, Weiner J, Heiker JT, Klöting N, Tönjes A, Stumvoll M, Blüher M, Mittag J, Krause K., Thyroid hormones regulate Zfp423 expression in regionally distinct adipose depots through direct and cell-autonomous action. Cell Rep. 2023 Feb 7;42(2):112088.  


Sacher J, Witte AV. Genetic heart-brain connections. Science. 2023 Jun 2;380(6648):897-898.


Schaefer SM, Kaiser A, Eichner G, Fasshauer M. Association of sugar intake from different sources with incident dementia in the prospective cohort of UK Biobank participants. Nutr J. 2023 Sep 4;22(1):42.


Schäffner E, Bosch-Queralt M, Edgar JM, Lehning M, Strauß J, Fleischer N, Kungl T, Wieghofer P, Berghoff SA, Reinert T, Krueger M, Morawski M, Möbius W, Barrantes-Freer A, Stieler J, Sun T, Saher G, Schwab MH, Wrede C, Frosch M, Prinz M, Reich DS, Flügel A, Stadelmann C, Fledrich R, Nave KA, Stassart RM. Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease. Nat Neurosci. 2023 Jul;26(7):1218-1228.


Schlögl H, Villringer A, Miehle K, Fasshauer M, Stumvoll M, Mueller K. Metreleptin Robustly Increases Resting-state Brain Connectivity in Treatment-naïve Female Patients With Lipodystrophy.  J Endocr Soc. 2023 Jun 6;7(8):bvad072.


Schönauer R, Jin W, Findeisen C, Valenzuela I, Devlin LA, Murrell J, Bedoukian EC, Pöschla L, Hantmann E, Riedhammer KM, Hoefele J, Platzer K, Biemann R, Campeau PM, Münch J, Heyne H, Hoffmann A, Ghosh A, Sun W, Dong H, Noé F, Wolfrum C, Woods E, Parker MJ, Neatu R, Le Guyader G, Bruel AL, Perrin L, Spiewak H; Genomics England Research Consortium; Missotte I, Fourgeaud M, Michaud V, Lacombe D, Paolucci SA, Buchan JG, Glissmeyer M, Popp B, Blüher M, Sayer JA, Halbritter J. Monoallelic intragenic POU3F2 variants lead to neurodevelopmental delay and hyperphagic obesity, confirming the gene's candidacy in 6q16.1 deletions. Am J Hum Genet. 2023 May 16:S0002-9297(23)00157-X.


Schroeter ML, Godulla J, Thiel F, Taskin B, Beutner F, Dubovoy VK, Teren A, Camilleri J, Eickhoff S, Villringer A, Mueller K. Heart failure decouples the precuneus in interaction with social cognition and executive functions. Sci Rep. 2023 Jan 23;13(1):1236.


Schürfeld R, Baratashvili E, Würfel M, Blüher M, Stumvoll M, Tönjes A, Ebert T. Circulating acyl-CoA-binding protein/diazepam-binding inhibitor in gestational diabetes mellitus. Reprod Biol Endocrinol. 2023 Oct 23;21(1):96.


Schürfeld R, Sandner B, Hoffmann A, Klöting N, Baratashvili E, Nowicki M, Paeschke S, Kosacka J, Kralisch S, Bachmann A, Frille A, Dietel A, Stolzenburg JU, Blüher M, Zhang MZ, Harris RC, Isermann B, Stumvoll M, Tönjes A, Ebert T. Renal function is a major predictor of circulating acyl-CoA-binding protein/diazepam-binding inhibitor. Front Endocrinol (Lausanne). 2023 May 23;14:1152444.


Stein R, Koutny F, Riedel J, Dörr N, Meyer K, Colombo M, Vogel M, Anderwald CH, Blüher M, Kiess W, Körner A, Weghuber D. Single Point Insulin Sensitivity Estimator (SPISE) As a Prognostic Marker for Emerging Dysglycemia in Children with Overweight or Obesity. Metabolites. 2023 Jan 7;13(1):100.


Stein R, Göpel E, Weghuber D, Hammel MC, Vogel M, Kiess W, Körner A. Are there relevant thresholds of insulin-independent indices across the lifespan to predict alterations in glycemic control?-Authors' reply. Lancet Reg Health Eur. 2023 Sep 6;33:100734.


Tindall CA, Möhlis K, Rapöhn I, Dommel S, Riedl V, Schneekönig M, Höfling C, Roßner S, Stichel J, Beck-Sickinger AG, Weiner J, Heiker JT. LRP1 is the cell-surface endocytosis receptor for vaspin in adipocytes. FEBS J. 2023 Nov 3.


Tsaban G, Shalev A, Katz A, Yaskolka Meir A, Rinott E, Zelicha H, Kaplan A, Wolak A, Bluher M, Stampfer MJ, Shai I. Effect of Lifestyle Modification and Green Mediterranean Diet on Proximal Aortic Stiffness. J Am Coll Cardiol. 2023 Apr 25;81(16):1659-1661.


Useini A, Engelberger F, Künze G, Sträter N., Structural basis of the activation of PPARγ by the plasticizer metabolites MEHP and MINCH. Environ Int. 2023 Feb 18;173:107822.


Weiner J, Dommel S, Gebhardt C, Hanschkow M, Popkova Y, Krause K, Klöting N, Blüher M, Schiller J, Heiker JT. Differential expression of immunoregulatory cytokines in adipose tissue and liver in response to high fat and high sugar diets in female mice. Frontiers in Nutrition (2023), 10:3389.


Wilde C, Chaudhry PM, Luo R, Simon KU, Piao X, Liebscher I. Collagen VI Is a Gi-Biased Ligand of the Adhesion GPCR GPR126/ADGRG6. Cells. 2023 Jun 5;12(11):1551.


Würfel M, Blüher M, Stumvoll M, Ebert T, Kovacs P, Tönjes A, Breitfeld J. Adipokines as Clinically Relevant Therapeutic Targets in Obesity. Biomedicines. 2023 May 11;11(5):1427.


Yaskolka Meir A, Keller M, Hoffmann A, Rinott E, Tsaban G, Kaplan A, Zelicha H, Hagemann T, Ceglarek U, Isermann B, Shelef I, Blüher M, Stumvoll M, Li J, Haange SB, Engelmann B, Rolle-Kampczyk U, von Bergen M, Hu FB, Stampfer MJ, Kovacs P, Liang L, Shai I. The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial. BMC Med. 2023 Sep 25;21(1):364.


Zhang X, Weiß T, Cheng MH, Chen S, Ambrosius CK, Czerniak AS, Li K, Feng M, Bahar I, Beck-Sickinger AG, Zhang C. Structural basis of CMKLR1 signaling induced by chemerin9. bioRxiv [Preprint]. 2023 Jun 10:2023.06.09.544295.


2022

Barth LAG, Nebe M, Kalwa H, Velluva A, Kehr S, Kolbig F, Prabutzki P, Kiess W, Le Duc D, Garten A, Kirstein AS. Phospholipid Scramblase 4 (PLSCR4) Regulates Adipocyte Differentiation via PIP3-Mediated AKT Activation. Int J Mol Sci. 2022 Aug 29;23(17):9787.


Begcevic Brkovic I, Zöhrer B, Scholz M, Reinicke M, Dittrich J, Kamalsada S, Baber R, Beutner F, Teren A, Engel C, Wirkner K, Thiele H, Löffler M, Riedel-Heller SG, Ceglarek U. Simultaneous Mass Spectrometry-Based Apolipoprotein Profiling and Apolipoprotein E Phenotyping in Patients with ASCVD and Mild Cognitive Impairment. Nutrients. 2022 Jun 15;14(12):2474. 


Belda E, Voland L, 〈...〉, Blüher M, Chakaroun R, Chilloux J, Coelho LP, Dao MC, Das P, Fellahi S, Forslund S, 〈...〉, Vieira-Silva S; MetaCardis Consortium, Galan P, Holst J, Gøtze JP, Køber L, Vestergaard H, Hansen T, Hercberg S, Oppert JM, Nielsen J, Letunic I, Dumas ME, Stumvoll M, Pedersen OB, Bork P, Ehrlich SD, Zucker JD, Bäckhed F, Raes J, Clément K. Impairment of gut microbial biotin metabolism and host biotin status in severe obesity: effect of biotin and prebiotic supplementation on improved metabolism. Gut. 2022 Jan 11;gutjnl-2021-325753.


Boeschen M, Le Duc D, Stiller M, von Laffert M, Schöneberg T, Horn S. Interactive webtool for analyzing drug sensitivity and resistance associated with genetic signatures of cancer cell lines. J Cancer Res Clin Oncol. 2022 Dec 6. 


Bohn C, Vogel M, Poulain T, Hiemisch A, Kiess W, Körner A. Having siblings promotes a more healthy weight status-Whereas only children are at greater risk for higher BMI in later childhood. PLoS One. 2022 Jul 19;17(7):e0271676.


Bondareva O, Rodríguez-Aguilera JR, Oliveira F, Liao L, Rose A, Gupta A, Singh K, Geier F, Schuster J, Boeckel JN, Buescher JM, Kohli S, Klöting N, Isermann B, Blüher M, Sheikh BN. Single-cell profiling of vascular endothelial cells reveals progressive organ-specific vulnerabilities during obesity. Nat Metab. 2022. Nov 18.


Christen L, Broghammer H, Rapöhn I, Möhlis K, Strehlau C, Ribas-Latre A, Gebhardt C, Roth L, Krause K, Landgraf K, Körner A, Rohde-Zimmermann K, Hoffmann A, Klöting N, Ghosh A, Sun W, Dong H, Wolfrum C, Rassaf T, Hendgen-Cotta UB, Stumvoll M, Blüher M, Heiker JT, Weiner J. Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans. Clin Transl Med. 2022 Dec;12(12):e1108.


Czerniak AS, Kretschmer K, Weiß T, Beck-Sickinger AG. The Chemerin Receptor CMKLR1 Requires Full-Length Chemerin for High Affinity in Contrast to GPR1 as Demonstrated by a New Nanoluciferase-Based Binding Assay. ChemMedChem. 2022 Sep 30:e202200413.


Emonds JJ, Ringel C, Reinicke M, Müller D, Von Eckardstein A, Meixensberger J, Ceglarek U, Gaudl A. Influence of Trimethylamine N-Oxide on Platelet Activation. Nutrients. 2022 Aug 10;14(16):3261. 


Fischer TF, Beck-Sickinger AG. Chemerin - exploring a versatile adipokine. Biol Chem. 2022 Jan 18.


Fries CM, Haange SB, Rolle-Kampczyk U, Till A, Lammert M, Grasser L, Medawar E, Dietrich A, Horstmann A, von Bergen M, Fenske WK. Metabolic Profile and Metabolite Analyses in Extreme Weight Responders to Gastric Bypass Surgery.  Metabolites . 2022 May 6;12(5):417. 


Heianza Y, Krohn K, Xue Q, Meir AY, Ziesche S, Ceglarek U, Blüher M, Keller M, Kovacs P, Shai I, Qi L. Changes in circulating MicroRNAs-99/100 and reductions of visceral and ectopic fat depots in response to lifestyle interventions: the CENTRAL trial. Am J Clin Nutr. 2022 Mar 28;nqac070.


Hinney A, Körner A, Fischer-Posovszky P. The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits. Nat Rev Endocrinol. 2022 Jul 28;1-15.


Hoang AC, Sasi-Szabó L, Pál T, Szabó T, Diedrich V, Herwig A, Landgraf K, Körner A, Röszer T. Mitochondrial RNA stimulates beige adipocyte development in young mice. Nat Metab. 2022 Nov 28.


Hofmann SM, Beyer F, Lapuschkin S, Goltermann O, Loeffler M, Müller KR, Villringer A, Samek W, Witte AV. Towards the Interpretability of Deep Learning Models for Multi-modal Neuroimaging: Finding Structural Changes of the Ageing Brain.  Neuroimage. 2022 Jul 23;119504.


Kaiser, A., Schaefer, S., Behrendt, I., Eichner, G., & Fasshauer, M. Association of all-cause mortality with sugar intake from different sources in the prospective cohort of UK Biobank participants. British Journal of Nutrition, 1-10. doi:10.1017/S0007114522003233


Karusheva Y, Ratcliff M, Mörseburg A, Barker P, Melvin A, Sattar N, Burling K, Backmark A, Roth R, Jermutus L, Guiu-Jurado E, Blüher M, Welsh P, Hyvönen M, O'Rahilly S. The Common H202D Variant in GDF-15 Does Not Affect Its Bioactivity but Can Significantly Interfere with Measurement of Its Circulating Levels. J Appl Lab Med. 2022 Jul 7


Kempf E, Landgraf K, Vogel T, Spielau U, Stein R, Raschpichler M, Kratzsch J, Kiess W, Stanik J, Körner A. Associations of GHR, IGF-1 and IGFBP-3 expression in adipose tissue cells with obesity-related alterations in corresponding circulating levels and adipose tissue function in children. Adipocyte. 2022 Dec;11(1):630-642.


Kempf E, Landgraf K, Stein R, Hanschkow M, Hilbert A, Abou Jamra R, Boczki P, Herberth G, Kühnapfel A, Tseng YH, Stäubert C, Schöneberg T, Kühnen P, Rayner NW, Zeggini E, Kiess W, Blüher M, Körner A. Aberrant expression of agouti signaling protein (ASIP) as a cause of monogenic severe childhood obesity. Nat Metab. 2022 Dec 19.  


Klemp I, Hoffmann A, Müller L, Hagemann T, Horn K, Rohde-Zimmermann K, Tönjes A, Thiery J, Löffler M, Burkhardt R, Böttcher Y, Stumvoll M, Blüher M, Krohn K, Scholz M, Baber R, Franks PW, Kovacs P, Keller M. DNA methylation patterns reflect individual's lifestyle independent of obesity. Clin Transl Med. 2022 Jun;12(6):e851. 


Klöting N, Schwarzer M, Heyne E, Ceglarek U, Hoffmann A, Krohn K, Doenst T, Blüher M. Intrinsic Exercise Capacity Affects Glycine and Angiotensin-Converting Enzyme 2 (ACE2) Levels in Sedentary and Exercise Trained Rats. Metabolites. 2022 Jun 15;12(6):548.


Körner MB, Velluva A, Bundalian L, Radtke M, Lin CC, Zacher P, Bartolomaeus T, Kirstein AS, Mrestani A, Scholz N, Platzer K, Teichmann AC, Hentschel J, Langenhan T, Lemke JR, Garten A, Abou Jamra R, Le Duc D. Altered gene expression profiles impair the nervous system development in individuals with 15q13.3 microdeletion. Sci Rep. 2022 Aug 5;12(1):13507


Kosacka J, Berger C, Ceglarek U, Hoffmann A, Blüher M, Klöting N. Ramipril Reduces Acylcarnitines and Distinctly Increases Angiotensin-Converting Enzyme 2 Expression in Lungs of Rats. Metabolites. 2022 Mar 26;12(4):293.


Landgraf K, Kühnapfel A, Schlanstein M, Biemann R, Isermann B, Kempf E, Kirsten H, Scholz M, Körner A. Transcriptome Analyses of Adipose Tissue Samples Identify EGFL6 as a Candidate Gene Involved in Obesity-Related Adipose Tissue Dysfunction in Children. Int J Mol Sci. 2022 Apr 14;23(8):4349.


Le Duc D, Velluva A, Cassatt-Johnstone M, Olsen RA, Baleka S, Lin CC, Lemke JR, Southon JR, Burdin A, Wang MS, Grunewald S, Rosendahl W, Joger U, Rutschmann S, Hildebrandt TB, Fritsch G, Estes JA, Kelso J, Dalén L, Hofreiter M, Shapiro B, Schöneberg T. Genomic basis for skin phenotype and cold adaptation in the extinct Steller's sea cow. Sci Adv. 2022 Feb 4;8(5):eabl6496.


Liebscher I, Schöneberg T, Thor D. Stachel-mediated activation of adhesion G protein-coupled receptors: insights from cryo-EM studies. Signal Transduct Target Ther. 2022 Jul 9;7(1):227.


Mai H, Rong Z, Zhao S, Cai R, Steinke H, Bechmann I, Ertürk A. Scalable tissue labeling and clearing of intact human organs. Nat Protoc. 2022 Jul 20.


Maixner N, Haim Y, Blüher M, Chalifa-Caspi V, Veksler-Lublinsky I, Makarenkov N, Yoel U, Bashan N, Liberty IF, Kukeev I, Dukhno O, Levy D, Rudich A. Visceral Adipose Tissue E2F1-miRNA206/210 Pathway Associates with Type 2 Diabetes in Humans with Extreme Obesity. Cells. 2022 Sep 29;11(19):3046.


Medawar E, Witte AV. Impact of obesity and diet on brain structure and function: a gut-brain-body crosstalk. Proc Nutr Soc. 2022 Nov 8;1-19.


Milani A, Morawski M, Bechmann I. Inter-hemispherical comparison of tau-pathology in the human temporal lobe. Ann Anat. 2022 Dec 30:152042.


Milek M, Moulla Y, Kern M, Stroh C, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dressler M, Kovacs P, Stumvoll M, Blüher M, Guiu-Jurado E.  Adipsin Serum Concentrations and Adipose Tissue Expression in People with Obesity and Type 2 Diabetes. Int J Mol Sci. 2022 Feb 17;23(4):2222.


Mitgau J, Franke J, Schinner C, Stephan G, Berndt S, Placantonakis DG, Kalwa H, Spindler V, Wilde C, Liebscher I. The N Terminus of Adhesion G Protein-Coupled Receptor GPR126/ADGRG6 as Allosteric Force Integrator. Front Cell Dev Biol. 2022 Jun 23;10:873278.


Münzker J, Haase N, Till A, Sucher R, Haange SB, Nemetschke L, Gnad T, Jäger E, Chen J, Riede SJ, Chakaroun R, Massier L, Kovacs P, Ost M, Rolle-Kampczyk U, Jehmlich N, Weiner J, Heiker JT, Klöting N, Seeger G, Morawski M, Keitel V, Pfeifer A, von Bergen M, Heeren J, Krügel U, Fenske WK. Functional changes of the gastric bypass microbiota reactivate thermogenic adipose tissue and systemic glucose control via intestinal FXR-TGR5 crosstalk in diet-induced obesity. Microbiome. 2022 Jun 24;10(1):96.


Neumann NJ, Fasshauer M. Added flavors: potential contributors to body weight gain and obesity? BMC Med. 2022 Nov 1;20(1):417. 


Neumann P, Lenz DE, Streit WJ, Bechmann I. Is microglial dystrophy a form of cellular senescence? An analysis of senescence markers in the aged human brain. Glia. 2022 Oct 26.


Nebe M, Kehr S, Schmitz S, Breitfeld J, Lorenz J, Le Duc D, Stadler PF, Meiler J, Kiess W, Garten A, Kirstein AS. Small integral membrane protein 10 like 1 enhances differentiation of adipose progenitor cells. Biochem Biophys Res Commun. 2022 Mar 4;604:57-62. 


Paolicelli R.C.,[...], Bechmann I, [...], Wyss-Coray T. Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 Nov 2;110(21):3458-3483. 


Pincu Y, Yoel U, Haim Y, Makarenkov N, Maixner N, Shaco-Levy R, Bashan N, Dicker D, Rudich A. Assessing Obesity-Related Adipose Tissue Disease (OrAD) to Improve Precision Medicine for Patients Living With Obesity. Front Endocrinol (Lausanne). 2022 Apr 29;13:860799.


Rinott E, Meir AY, Tsaban G, Zelicha H, Kaplan A, Knights D, Tuohy K, Scholz MU, Koren O, Stampfer MJ, Wang DD, Shai I, Youngster I. The effect of the green-mediterranean diet on cardiometabolic health are linked to gut micorbiome modifications. Genome Med. 2022 Mar 10;14(1):29.


Schaefer SM, Kaiser A, Behrendt I, Eichner G, Fasshauer M. Association of alcohol types, coffee and tea intake with mortality: prospective cohort study of UK Biobank participants. Br J Nutr. 2022 Feb 3;1-11.


Schaefer SM, Kaiser A, Behrendt I, Eichner G, Fasshauer M. Association of Alcohol Types, Coffee, and Tea Intake with Risk of Dementia: Prospective Cohort Study of UK Biobank Participants. Brain Sci. 2022 Mar 8;12(3):360.


Schaffert A, Karkossa I, Ueberham E, Schlichting R, Walter K, Arnold J, Blüher M, Heiker JT, Lehmann J, Wabitsch M, Escher BI, von Bergen M, Schubert K.Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes. Environ Int. 2022 Jun;164:107279.


Scholz M, Horn K, Pott J, Gross A, Kleber ME, Delgado GE, Mishra PP, Kirsten H, Gieger C, Müller-Nurasyid M, Tönjes A, Kovacs P, Lehtimäki T, Raitakari O, Kähönen M, Gylling H, Baber R, Isermann B, Stumvoll M, Loeffler M, März W, Meitinger T, Peters A, Thiery J, Teupser D, Ceglarek U. Genome-wide meta-analysis of phytosterols reveals five novel loci and a detrimental effect on coronary atherosclerosis. Nat Commun. 2022 Jan 10;13(1):143.


Schroeter ML, Kynast J, Schlögl H, Baron-Cohen S, Villringer A. Sex and age interact in reading the mind in the eyes. Compr Psychoneuroendocrinol. 2022 Nov 9;12:100162. 


Stephan G, Frenster JD, Liebscher I, Placantonakis DG. Activation of the adhesion G protein-coupled receptor GPR133 (ADGRD1) by antibodies targeting its N-terminus. J Biol Chem. 2022 Apr 18;101949.


Stürzebecher PE, Kralisch S, Schubert MR, Filipova V, Hoffmann A, Blüher M, Miehle K, Ebert T, Laufs U, Tönjes A, Boeckel J-N. Leptin Treatment Has Vasculoprotective Effects in Lipodystrophic Mice. P N A S U S A. 2022 Oct 4;119(40):e2110374119.


Sun C, Förster F, Gutsmann B, Moulla Y, Stroh C, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dressler M, Stumvoll M, Blüher M, Kovacs P, Breitfeld J, Guiu-Jurado E. Metabolic Effects of the Waist-To-Hip Ratio Associated Locus GRB14/COBLL1 Are Related to GRB14 Expression in Adipose Tissue. Int J Mol Sci. 2022 Aug 2;23(15):8558.


Vieira DB, Antel J, Peters T, Miehle K, Stumvoll M, Hebebrand J, Schlögl H. Suggestive evidence for an antidepressant effect of metreleptin treatment in patients with lipodystrophy. Obes Facts . 2022 Aug 29.


de Vries K, Medawar E, Korosi A, Witte A. V. The effect of polyphenols on working and episodic memory in non-pathological and pathological aging: a systematic review and meta-analysis. Front. Nutr., 26 January 2022. 


Wagner IV, Savchuk I, Sahlin L, Kulle A, Klöting N, Dietrich A, Holterhus PM, Dötsch J, Blüher M, Söder O. De-novo and depot-specific androgen production in human adipose tissue - a source of hyperandrogenism in women with obesity. Obes Facts. 2022 Jan 4. doi: 10.1159/000521571.


Wang X, Li Y, Qiang G, Wang K, Dai J, McCann M, Munoz MD, Gil V, Yu Y, Li S, Yang Z, Xu S, Cordoba-Chacon J, De Jesus DF, Sun B, Chen K, Wang Y, Liu X, Miao Q, Zhou L, Hu R, Ding Q, Kulkarni RN, Gao D, Blüher M, Liew CW. Secreted EMC10 is upregulated in human obesity and its neutralizing antibody prevents diet-induced obesity in mice. Nat Commun. 2022 Nov 28;13(1):7323.


Wittekind DA, Kratzsch J, Biemann R, Mergl R, Riedel-Heller S, Witte V, Villringer A, Kluge M. Association Between Self-rating Depression Scores and Total Ghrelin and Adipokine Serum Levels in a Large Population-Based Sample. Front Psychiatry. 2022 May 11;13:891325.


Yang CH, Fagnocchi L, Apostle S, Wegert V, Casaní-Galdón S, Landgraf K, Panzeri I, Dror E, Heyne S, Wörpel T, Chandler DP, Lu D, Yang T, Gibbons E, Guerreiro R, Bras J, Thomasen M, Grunnet LG, Vaag AA, Gillberg L, Grundberg E, Conesa A, Körner A; PERMUTE, Pospisilik JA. Independent phenotypic plasticity axes define distinct obesity sub-types. Nat Metab. 2022 Sep 12. 


Yengo L, [...], Scholz M, [...], Hirschhorn JN. A saturated map of common genetic variants associated with human height. Nature. 2022 Oct;610(7933):704-712. doi: 10.1038/s41586-022-05275-y. Epub 2022 Oct 12. PMID: 36224396; PMCID: PMC9605867.


Zelicha H, Kloting N, Kaplan A, Yaskolka Meir A, Rinott E, Tsaban G, Chassidim Y, Blueher M, Ceglarek U, Isermann B, Stumvoll M, Quayson RN, von Bergen M, Engelmann B, Rolle-Kampczyk UE, Haange SB, Tuohy KM, Diotallevi C, Shelef I, Hu FB, Stampfer MJ, Shai I. The effect of high-polyphenol Mediterranean diet on visceral adiposity: the DIRECT PLUS randomized controlled trial. BMC Med. 2022 Sep 30;20(1):327


2021

Berger C, Klöting N. Leptin Receptor Compound Heterozygosity in Humans and Animal Models. Int J Mol Sci. 2021 Apr 25;22(9):4475.


Berger C, Heyne HO, Heiland T, Dommel S, Höfling C, Guiu-Jurado E, Roßner S, Dannemann M, Kelso J, Kovacs P, Blüher M, Klöting N. A novel compound heterozygous leptin receptor mutation causes more severe obesity than in Lepr db/db mice. J Lipid Res. 2021 Aug 11:100105. 


Brinker G, Froeba J, Arndt L, Braune J, Hobusch C, Lindhorst A, Bechmann I, Gericke M. CD4+ T cells regulate glucose homeostasis independent of adipose tissue dysfunction in mice. Eur J Immunol. 2021 Mar 30.


Chakaroun RM, Massier L, Heintz-Buschart A, Said N, Fallmann J, Crane A, Schütz T, Dietrich A, Blüher M, Stumvoll M, Musat N, Kovacs P. Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery. Genome Med. 2021 Jun 22;13(1):105.


Chen J, Haase N, Haange SB, Sucher R, Münzker J, Jäger E, Schischke K, Seyfried F, von Bergen M, Hankir MK, Krügel U, Fenske WK. Roux-en-Y gastric bypass contributes to weight loss-independent improvement in hypothalamic inflammation and leptin sensitivity through gut-microglia-neuron-crosstalk. Mol Metab. 2021 Mar 16:101214.


Chen J, … Kiess W, … Körner A, Kovacs P,…, Stumvoll M, …Tönjes A,... , Barroso I. The trans-ancestral genomic architecture of glycemic traits. Nat Genet. 2021 Jun;53(6):840-860.


Dommel S, Blüher M. Does C-C Motif Chemokine Ligand 2 (CCL2) Link Obesity to a Pro-Inflammatory State? Int J Mol Sci. 2021 Feb 2;22(3):1500.


Dommel S, Hoffmann A, Berger C, Kern M, Klöting N, Kannt A, Blüher M. Effects of Whole-Body Adenylyl Cyclase 5 ( Adcy5) Deficiency on Systemic Insulin Sensitivity and Adipose Tissue. Int J Mol Sci. 2021 Apr 21;22(9):4353.


Ecker J, Benedetti E, Kindt ASD, Höring M, Perl M, Machmüller AC, Sichler A, Plagge J, Wang Y, Zeissig S, Shevchenko A, Burkhardt R, Krumsiek J, Liebisch G, Janssen KP. The colorectal cancer lipidome - identification of a robust tumor-specific lipid species signature. Gastroenterology. 2021 May 14:S0016-5085(21)02979-6.


Engel KM, Schiller J, Galuska CE, Fuchs B. Phospholipases and Reactive Oxygen Species Derived Lipid Biomarkers in Healthy and Diseased Humans and Animals - A Focus on Lysophosphatidylcholine.Front Physiol. 2021 Nov 10;12:732319.


Epperlein S, Gebhardt C, Rohde K, Chakaroun R, Patt M, Schamarek I, Kralisch S, Heiker JT, Scholz M, Stumvoll M, Kovacs P, Breitfeld J, Tönjes A. The Effect of FGF21 and Its Genetic Variants on Food and Drug Cravings, Adipokines and Metabolic Traits. Biomedicines. 2021 Mar 29;9(4):345.


Favara DM, Liebscher I, Jazayeri A, Nambiar M, Sheldon H, Banham AH, Harris AL. Elevated expression of the adhesion GPCR ADGRL4/ELTD1 promotes endothelial sprouting angiogenesis without activating canonical GPCR signalling. Sci Rep. 2021 Apr 23;11(1):8870. 


Fischer TF, Czerniak AS, Weiß T, Schoeder CT, Wolf P, Seitz O, Meiler J, Beck-Sickinger AG. Ligand-binding and -scavenging of the chemerin receptor GPR1. Cell Mol Life Sci. 2021 Jul 9.  


Fischer TF, Czerniak AS, Weiß T, Zellmann T, Zielke L, Els-Heindl S, Beck-Sickinger AG. Cyclic Derivatives of the Chemerin C-Terminus as Metabolically Stable Agonists at the Chemokine-like Receptor 1 for Cancer Treatment.  Cancers (Basel) . 2021 Jul 27;13(15):3788.


Fischer TF, Schoeder CT, Zellmann T, Stichel J, Meiler J, Beck-Sickinger AG. Cyclic Analogues of the Chemerin C-Terminus Mimic a Loop Conformation Essential for Activating the Chemokine-like Receptor 1. J Med Chem. 2021 Mar 25;64(6):3048-3058.


Forslund SK, Chakaroun R, Zimmermann-Kogadeeva M, Markó L, Aron-Wisnewsky J, Nielsen T, Moitinho-Silva L, Schmidt TSB, Falony G, Vieira-Silva S, Adriouch S, Alves RJ, Assmann K, Bastard JP, Birkner T, Caesar R, Chilloux J, Coelho LP, Fezeu L, Galleron N, Helft G, Isnard R, Ji B, Kuhn M, Le Chatelier E, Myridakis A, Olsson L, Pons N, Prifti E, Quinquis B, Roume H, Salem JE, Sokolovska N, Tremaroli V, Valles-Colomer M, Lewinter C, Søndertoft NB, Pedersen HK, Hansen TH; MetaCardis Consortium*, Gøtze JP, Køber L, Vestergaard H, Hansen T, Zucker JD, Hercberg S, Oppert JM, Letunic I, Nielsen J, Bäckhed F, Ehrlich SD, Dumas ME, Raes J, Pedersen O, Clément K, Stumvoll M, Bork P. Combinatorial, additive and dosedependent drug–microbiome associations. Nature. 2021 Dec 8.


Frenster JD, Stephan G, Ravn-Boess N, Bready D, Wilcox J, Kieslich B, Wilde C, Sträter N, Wiggin GR, Liebscher I, Schöneberg T, Placantonakis DG. Functional impact of intramolecular cleavage and dissociation of adhesion G protein-coupled receptor GPR133 (ADGRD1) on canonical signaling. J Biol Chem. 2021 May 19:100798.


Georgiadi A, Lopez-Salazar V, Merahbi RE, Karikari RA, Ma X, Mourão A, Klepac K, Bühler L, Alfaro AJ, Kaczmarek I, Linford A, Bosma M, Shilkova O, Ritvos O, Nakamura N, Hirose S, Lassi M, Teperino R, Machado J, Scheideler M, Dietrich A, Geerlof A, Feuchtinger A, Blutke A, Fischer K, Müller TD, Kessler K, Schöneberg T, Thor D, Hornemann S, Kruse M, Nawroth P, Pivovarova-Ramich O, Pfeiffer AFH, Sattler M, Blüher M, Herzig S. Orphan GPR116 mediates the insulin sensitizing effects of the hepatokine FNDC4 in adipose tissue. Nat Commun. 2021 May 20;12(1):2999.


Gjermeni E, Kirstein AS, Kolbig F, Kirchhof M, Bundalian L, Katzmann JL, Laufs U, Blüher M, Garten A, Le Duc D. Obesity-An Update on the Basic Pathophysiology and Review of Recent Therapeutic Advances. Biomolecules. 2021 Sep 29;11(10):1426.


Hanschkow M, Boulet N, Kempf E, Bouloumié A, Kiess W, Stein R, Körner A, Landgraf K. Expression of the adipocyte progenitor markers MSCA1 and CD36 is associated with adipose tissue function in children. J Clin Endocrinol Metab. 2021 Aug 27.

Heinrichs HS, Beyer F, Medawar E, Prehn K, Ordemann J, Flöel A, Witte AV. Effects of bariatric surgery on functional connectivity of the reward and default mode network: A pre-registered analysis. Hum Brain Mapp . 2021 Aug 25.


Hoffmann A, Ebert T, Hankir MK, Flehmig G, Klöting N, Jessnitzer B, Lössner U, Stumvoll M, Blüher M, Fasshauer M, Tönjes A, Miehle K, Kralisch S. Leptin Improves Parameters of Brown Adipose Tissue Thermogenesis in Lipodystrophic Mice. Nutrients. 2021 Jul 22;13(8):2499. 

Höring M, Ejsing CS, Krautbauer S, Ertl VM, Burkhardt R, Liebisch G. Accurate quantification of lipid species affected by isobaric overlap in Fourier-Transform mass spectrometry. J Lipid Res. 2021 Feb 15:100050.


Höring M, Krautbauer S, Hiltl L, Babl V, Sigruener A, Burkhardt R, Liebisch G. Accurate Lipid Quantification of Tissue Homogenates Requires Suitable Sample Concentration, Solvent Composition, and Homogenization Procedure-A Case Study in Murine Liver. Metabolites . 2021 Jun 8;11(6):365. 


Kaczmarek I, Suchý T, Prömel S, Schöneberg T, Liebscher I, Thor D. The relevance of adhesion G protein-coupled receptors in metabolic functions.Biol Chem. 2021 Jul 5.  


Kempf E, Vogel M, Vogel T, Kratzsch J, Landgraf K, Kühnapfel A, Gausche R, Gräfe D, Sergeyev E, Pfäffle R, Kiess W, Stanik J, Körner A. Dynamic alterations in linear growth and endocrine parameters in children with obesity and height reference values. EClinicalMedicine. 2021 Jun 23;37:100977.


Kirstein AS, Kehr S, Nebe M, Hanschkow M, Barth LAG, Lorenz J, Penke M, Breitfeld J, Le Duc D, Landgraf K, Körner A, Kovacs P, Stadler PF, Kiess W, Garten A. PTEN regulates adipose progenitor cell growth, differentiation, and replicative aging. J Biol Chem. 2021 Jul 14;297(2):100968.


Kolora SRR, Gysi DM, Schaffer S, Grimm-Seyfarth A, Szabolcs M, Faria R, Henle K, Stadler PF, Schlegel M, Nowick K. Accelerated evolution of tissue-specific genes mediates divergence amidst gene flow in European green lizards. Genome Biol Evol. 2021 May 14:evab109.


Koutny F, Stein R, Kiess W, Weghuber D, Körner A. Elevated transaminases potentiate the risk for emerging dysglycemia in children with overweight and obesity. Pediatr Obes. 2021 Jun 21;e12822. 


Krautbauer S, Blazquez R, Liebisch G, Hoering M, Neubert P, Pukrop T, Burkhardt R, Sigruener A. Application of Lipid Class Ratios for Sample Stability Monitoring-Evaluation of Murine Tissue Homogenates and SDS as a Stabilizer. Metabolites. 2021 Apr 27;11(5):277.


Krieg L, Didt K, Karkossa I, Bernhart SH, Kehr S, Subramanian N, Lindhorst A, Schaudinn A, Tabei S, Keller M, Stumvoll M, Dietrich A, von Bergen M, Stadler PF, Laurencikiene J, Krüger M, Blüher M, Gericke M, Schubert K, Kovacs P, Chakaroun R, Massier L. Gut. 2021 Oct 1:gutjnl-2021-324603.


van Krieken PP, Odermatt TS, Borsigova M, Blüher M, Wueest S, Konrad D. Oncostatin M suppresses browning of white adipocytes via gp130-STAT3 signaling. Mol Metab. 2021 Sep 18:101341.

Kunath A, Weiner J, Krause K, Rehders M, Pejkovska A, Gericke M, Biniossek ML, Dommel S, Kern M, Ribas-Latre A, Schilling O, Brix K, Stumvoll M, Klöting N, Heiker JT, Blüher M. Role of Kallikrein 7 in Body Weight and Fat Mass Regulation. Biomedicines 2021, 9, 131.


Leyh J, Paeschke S, Mages B, Michalski D, Nowicki M, Bechmann I, Winter K. Classification of Microglial Morphological Phenotypes Using Machine Learning. Front Cell Neurosci. 2021 Jun 29;15:701673. 


Leyh J, Winter K, Reinicke M, Ceglarek U, Bechmann I, Landmann J. Long-term diet-induced obesity does not lead to learning and memory impairment in adult mice. PLoS One. 2021 Sep 29;16(9):e0257921. 


Lindhorst A, Raulien N, Wieghofer P, Eilers J, Rossi FMV, Bechmann I, Gericke M. Adipocyte death triggers a pro-inflammatory response and induces metabolic activation of resident macrophages. Cell Death Dis . 2021 Jun 5;12(6):579. 


Massier L, Blüher M, Kovacs P, Chakaroun RM. Impaired Intestinal Barrier and Tissue Bacteria: Pathomechanisms for Metabolic Diseases. Front Endocrinol (Lausanne). 2021 Mar 9;12:616506.


McCann MA, Li Y, Muñoz M, Gil V, Qiang G, Cordoba-Chacon J, Blüher M, Duncan S, Liew CW. Adipose expression of CREB3L3 modulates body weight during obesity. Sci Rep. 2021 Sep 29;11(1):19400.


Meir A Y,  Keller Maria,  Bernhart S H,  Rinott E,  Tsaban G,  Zelicha H, Kaplan A, Schwarzfuchs D, Shelef I, Gepner Y, Li J,  Lin Y, Blüher M, Ceglarek U, Stumvoll M, Stadler P F, Stampfer M J, Kovacs P, Liang L, Shai I. Lifestyle weight‑loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial. Clin Epigenetics. 2021 Mar 4;13(1):48.


Nono Nankam PA, Nguelefack TB, Goedecke JH, Blüher M. Contribution of Adipose Tissue Oxidative Stress to Obesity-Associated Diabetes Risk and Ethnic Differences: Focus on Women of African Ancestry. Antioxidants (Basel). 2021 Apr 19;10(4):622.


Nono Nankam PA, Blüher M. Retinol-binding protein 4 in obesity and metabolic dysfunctions. Mol Cell Endocrinol. 2021 May 3:111312. 


Reinicke M, Leyh J, Zimmermann S, Chey S, Brkovic IB, Wassermann C, Landmann J, Lütjohann D, Isermann B, Bechmann I, Ceglarek U. Plant Sterol-Poor Diet Is Associated with Pro-Inflammatory Lipid Mediators in the Murine Brain. Int J Mol Sci. 2021 Dec 8;22(24):13207


Ribas-Latre A, Santos RB, Fekry B, Tamim YM, Shivshankar S, Mohamed AMT, Baumgartner C, Kwok C, Gebhardt C, Rivera A, Gao Z, Sun K, Heiker JT, Snyder BE, Kolonin MG, Eckel-Mahan KL. Cellular and physiological circadian mechanisms drive diurnal cell proliferation and expansion of white adipose tissue. Nat Commun . 2021 Jun 9;12(1):3482.   


Rinott E, Youngster I, Meir AY, Tsaban G, Kaplan A, Zelicha H, Rubin E, Koren O, Shai I. Autologous fecal microbiota transplantation can retain the metabolic achievements of dietary interventions. Eur J Intern Med. 2021 Apr 18:S0953-6205(21)00110-2. 


Rinott E,Youngster I, Meir AY, Tsaban G, Zelicha H, Kaplan A, Knights D,Tuohy K, Fava F, Scholz MU, Ziv O, Reuven E, Tirosh A, Rudich ABlüher MStumvoll MCeglarek U, Clement K, Koren O, Wang DD, Hu FB, Stampfer MJ, Shai I. Effects of Diet-Modulated Autologous Fecal Microbiota Transplantation on Weight Regain. Gastroenterology. 2021 Jan;160(1):158-173.e10.


Rønningen T, Dahl MB, Valderhaug TG, Cayir A, Keller M, Tönjes A, Blüher M, Böttcher Y. m6A Regulators in Human Adipose Tissue - Depot-Specificity and Correlation With Obesity. Front Endocrinol (Lausanne). 2021 Dec 7;12:778875.


Schaffert A, Krieg L, Weiner J, Schlichting R, Ueberham E, Karkossa I, Bauer M, Landgraf K, Junge KM, Wabitsch M, Lehmann J, Escher BI, Zenclussen AC, Körner A, Blüher M, Heiker JT, von Bergen M, Schubert K. Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation. Environ. Int. 2021 Jun 27;156:106730.


Schaffert A, Arnold J, Karkossa I, Blüher M, von Bergen M, Schubert K. The Emerging Plasticizer Alternative DINCH and Its Metabolite MINCH Induce Oxidative Stress and Enhance Inflammatory Responses in Human THP-1 Macrophages. Cells. 2021 Sep 9;10(9):2367.


Schöneberg T, Liebscher I. Mutations in G Protein-Coupled Receptors: Mechanisms, Pathophysiology and Potential Therapeutic Approaches. Pharmacol Rev. 2021 Jan;73(1):89-119.


Schroeter ML, Kynast J, Villringer A, Baron-Cohen S. Face Masks Protect From Infection but May Impair Social Cognition in Older Adults and People With Dementia. Front Psychol. 2021 Aug 13;12:640548.


Streit WJ, Rotter J, Winter K, Müller W, Khoshbouei H, Bechmann I. Droplet Degeneration of Hippocampal and Cortical Neurons Signifies the Beginning of Neuritic Plaque Formation. J Alzheimers Dis. 2021 Dec 22. 


Suchý T, Kaczmarek I, Maricic T, Zieschang C, Schöneberg T, Thor D, Liebscher I.Evaluating the feasibility of Cas9 overexpression in 3T3-L1 cells for generation of genetic knock-out adipocyte cell lines. Adipocyte. 2021 Dec;10(1):631-645.


Sun C, Kovacs P, Guiu-Jurado E. Genetics of Body Fat Distribution: Comparative Analyses in Populations with European, Asian and African Ancestries. Genes (Basel). 2021 May 29;12(6):841.


Thieleking R, Zhang R, Paerisch M, Wirkner K, Anwander A, Beyer F, Villringer A, Witte AV. Same Brain, Different Look?-The Impact of Scanner, Sequence and Preprocessing on Diffusion Imaging Outcome Parameters. J Clin Med. 2021 Oct 27;10(21):4987.


Tindall CA, Erkner E, Stichel J, Beck-Sickinger AG, Hoffmann A, Weiner J, Heiker JT. Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes. Adipocyte. 2021 Dec;10(1):216-231.


Velluva A, Radtke M, Horn S, Popp B, Platzer K, Gjermeni E, Lin CC, Lemke JR, Garten A, Schöneberg T, Blüher M, Abou Jamra R, Le Duc D. Phenotype-tissue expression and exploration (PTEE) resource facilitates the choice of tissue for RNA-seq-based clinical genetics studies. BMC Genomics. 2021 Nov 7;22(1):802.


Vieira-Silva S, Falony G, Belda E, Nielsen T, Aron-Wisnewsky J, Chakaroun R, Forslund SK, Assmann K, Valles-Colomer M, Nguyen TTD, Proost S, Prifti E, Tremaroli V, Pons N, Le Chatelier E, Andreelli F, Bastard JP, Coelho LP, Galleron N, Hansen TH, Hulot JS, Lewinter C, Pedersen HK, Quinquis B, Rouault C, Roume H, Salem JE, Søndertoft NB, Touch S; MetaCardis Consortium, Dumas ME, Ehrlich SD, Galan P, Gøtze JP, Hansen T, Holst JJ, Køber L, Letunic I, Nielsen J, Oppert JM, Stumvoll M, Vestergaard H, Zucker JD, Bork P, Pedersen O, Bäckhed F, Clément K, Raes J. Statin therapy is associated with lower prevalence of gut microbiota dysbiosis. Nature. 2020 May;581(7808):310-315.


Vogel M, Geserick M, Gausche R, Beger C, Poulain T, Meigen C, Körner A, Keller E, Kiess W, Pfäffle R. Age- and weight group-specific weight gain patterns in children and adolescents during the 15 years before and during the COVID-19 pandemic. Int J Obes (Lond). 2021 Sep 23;1-9.


Weiner J, Roth L, Kranz M, Brust P, Boelen A, Klöting N, Heiker JT, Blüher M, Tönjes A, Pfluger PT, Stumvoll M, Mittag J, Krause K. Leptin counteracts hypothermia in hypothyroidism through its pyrexic effects and by stabilizing serum thyroid hormone levels. Mol Metab. 2021 Oct 2:101348. 


Wittlake A, Prömel S, Schöneberg T. The Evolutionary History of Vertebrate Adhesion GPCRs and Its Implication on Their Classification. Int J Mol Sci. 2021 Oct 30;22(21):11803. 


Würfel M, Breitfeld J, Gebhard C, Scholz M, Baber R, Riedel-Heller SG, Blüher M, Stumvoll M, Kovacs P, Tönjes A. Interplay between adipose tissue secreted proteins, eating behavior and obesity. Eur J Nutr. 2021 Oct 12.


Yaskolka Meir A, Keller M, Bernhart SH, Rinott E, Tsaban G, Zelicha H, Kaplan A, Schwarzfuchs D, Shelef I, Gepner Y, Li J, Lin Y, Blüher M, Ceglarek UStumvoll MStadler PF, Stampfer MJ, Kovacs P, Liang L, Shai I. Lifestyle weight-loss intervention may attenuate methylation aging: the CENTRAL MRI randomized controlled trial. Clin Epigenetics. 2021 Mar 4;13(1):48.


Yaskolka Meir A, Keller M, Müller L, Bernhart SH, Tsaban G, Zelicha H, Rinott E, Kaplan A, Gepner Y, Shelef I, Schwarzfuchs D, Ceglarek U, Stadler P, Blüher M, Stumvoll M, Kovacs P, Shai I. Effects of lifestyle interventions on epigenetic signatures of liver fat: CENTRAL randomized controlled trial. Liver Int. 2021 May 3.


Yaskolka Meir A, Rinott E, Tsaban G, Zelicha H, Kaplan A, Rosen P, Shelef I, Youngster I, Shalev A, Blüher M, Ceglarek U, Stumvoll M, Tuohy K, Diotallevi C, Vrhovsek U, Hu F, Stampfer M, Shai I. Effect of green-Mediterranean diet on intrahepatic fat: the DIRECT PLUS randomised controlled trial. Gut. 2021 Jan 18:gutjnl-2020-323106.


Yaskolka Meir A, Tuohy K, von Bergen M, Krajmalnik-Brown R, Heinig U, Zelicha H, Tsaban G, Rinott E, Kaplan A, Aharoni A, Zeibich L, Chang D, Dirks B, Diotallevi C, Arapitsas P, Vrhovsek U, Ceglarek U, Haange SB, Rolle-Kampczyk U, Engelmann B, Lapidot M, Colt M, Sun Q, Shai I. The Metabolomic-Gut-Clinical Axis of Mankai Plant-Derived Dietary Polyphenols. Nutrients. 2021 May 30;13(6):1866. 

2020

Abshagen K, Berger C, Dietrich A, Schütz T, Wittekind C, Stumvoll M, Blüher M, Klöting N. A Human REPIN1 Gene Variant: Genetic Risk Factor for the Development of Nonalcoholic Fatty Liver Disease. Clin Transl Gastroenterol. 2020 Jan;11(1):e00114.


Aberle J, Lautenbach A, Meyhöfer S, Schmid SM, Selig L, Blüher M. Obesity and Diabetes. Exp Clin Endocrinol Diabetes. 2020 Dec 22. 


Al E, Iliopoulos F, Forschack N, Nierhaus T, Grund M, Motyka P, Gaebler M, Nikulin VV, Villringer A. Heart–brain interactions shape somatosensory perception and evoked potentials. Proc Natl Acad Sci U S A. 2020 Apr 27. pii: 201915629.


Asimakopoulou A, Engel KM, Gassler N, Bracht T, Sitek B, Buhl EM, Kalampoka S, Pinoé-Schmidt M, van Helden J, Schiller J, Weiskirchen R. Cells. 2020 May 28;9(6)E:1346.


Behrendt I, Eichner G, Fasshauer M. Association of Antioxidants Use with All-Cause and Cause-Specific Mortality: A Prospective Study of the UK Biobank. Antioxidants (Basel). 2020 Dec 16;9(12):1287.


Behrendt I, Fasshauer M, Eichner G. Gluten intake and metabolic health: conflicting findings from the UK Biobank. Eur J Nutr. 2020 Aug 6.


Beyer F, Prehn K, Wüsten KA, Villringer A, Ordemann J, Flöel A, Witte AV. Weight loss reduces head motion: Revisiting a major confound in neuroimaging. Hum Brain Mapp. 2020 Apr 2.


Beyer F, Zhang R, Scholz M, Wirkner K, Loeffler M, Stumvoll M, Villringer A, Witte AV.Higher BMI, but not obesity-related genetic polymorphisms, correlates with lower structural connectivity of the reward network in a population-based study. Int J Obes (Lond). 2020 Oct 25.


Bhattarai S, Pippel J, Scaletti E, Idris R, Freundlieb M, Rolshoven G, Renn C, Lee SY, Abdelrahman A, Zimmermann H, El-Tayeb A, Müller CE, Sträter N. 2-Substituted α,β-Methylene-ADP Derivatives: Potent Competitive Ecto-5'-nucleotidase (CD73) Inhibitors with Variable Binding Modes. J Med Chem. 2020 Feb 28.


Blucher C, Iberl S, Schwagarus N, Muller S, Liebisch G, Horing M, Hidrobo MS, Ecker J, Spindler N, Dietrich A, Burkhardt R, Stadler SC.Secreted factors from adipose tissue reprogram tumor lipid metabolism and induce motility by modulating PPARα/ANGPTL4 and FAK. Mol Cancer Res. 2020 Aug 28:molcanres.1223.2019.


Blüher M. Metabolically Healthy Obesity. Endocr Rev. 2020 May 1;41(3).


Bohn C, Vogel M, Spielau U, Hilbert C, Kiess W, Körner A.Birth weight increases with birth order despite decreasing maternal pregnancy weight gain. Acta Paediatrica 2020 Sept.


Braune J, Lindhorst A, Fröba J, Hobusch C, Kovacs P, Blüher M, Eilers J, Bechmann I, Gericke M. Multinucleated Giant Cells in Adipose Tissue are Specialized in Adipocyte Degradation. Diabetes. 2020 Nov 6:db200293.


Breitfeld J, Kehr S, Müller L, Stadler PF, Böttcher Y, Blüher M, Stumvoll M, Kovacs P. Developmentally Driven Changes in Adipogenesis in Different Fat Depots Are Related to Obesity. Front Endocrinol (Lausanne). 2020 Mar 26;11:138.


Buhl JP, Garten A, Kratzsch J, Kiess W, Penke M. How Reliable are Commercially Available Glypican4 ELISA Kits? Exp Clin Endocrinol Diabetes. 2020 Oct 16.  


Chakaroun RM, Massier L, Kovacs P. Gut Microbiome, Intestinal Permeability, and Tissue Bacteria in Metabolic Disease: Perpetrators or Bystanders? Nutrients. 2020 Apr 14;12(4). 


Dankel SN, Grytten E, Bjune JI, Nielsen HJ, Dietrich A, Blüher M, Sagen JV, Mellgren G. COL6A3 expression in adipose tissue cells is associated with levels of the homeobox transcription factor PRRX1. Sci Rep. 2020 Nov 19;10(1):20164. 


Dommel S, Berger C, Kunath A, Kern M, Gericke M, Kovacs P, Guiu-Jurado E, Klöting N, Blüher M. The Fabp4-Cre-model is insufficient to study Hoxc9 function in adipose tissue. Biomedicines . 2020 Jun 29;8(7):E184. 


Ertl VM, Höring M, Schött HF, Blücher C, Kjølbæk L, Astrup A, Burkhardt R, Liebisch G. Quantification of diacylglycerol and triacylglycerol species in human fecal samples by flow injection Fourier transform mass spectrometry. Anal Bioanal Chem. 2020 Mar 21.


Engel KM, Dzyuba V, Borys D, Schiller J. Different Glycolipids in Sperm From Different Freshwater Fishes - A High Performance Thin-Layer chromatography/electrospray Ionization-Mass Spectrometry StudRapidy. Commun Mass Spectrom. 2020 Jul 4;e8875.

 

Esefeld K, Kress S, Behrens M, Zimmer P, Stumvoll M, Thurm U, Gehr B, Brinkmann C, Halle M. Diabetes, Sports and Exercise. Exp Clin Endocrinol Diabetes. 2020 Dec 21.

Farag MA, Abdelwareth A, Sallam IE, El Shorbagi M, Jehmlich N, Fritz-Wallace K, Serena Schäpe S, Rolle-Kampczyk U, Ehrlich A, Wessjohann LA, von Bergen M. Metabolomics reveals impact of seven functional foods on metabolic pathways in a gut microbiota model.  J Adv Res. 2020 Jan 3;23:47-59.


Frenster JD, Kader M, Kamen S, Sun J, Chiriboga L, Serrano J, Bready D, Golub D, Ravn-Boess N, Stephan G, Chi AS, Kurz SC, Jain R, Park CY, Fenyo D, Liebscher I, Schöneberg T, Wiggin G, Newman R, Barnes M, Dickson JK, MacNeil DJ, Huang X, Shohdy N, Snuderl M, Zagzag D, Placantonakis DG. Expression profiling of the adhesion G protein-coupled receptor GPR133 (ADGRD1) in glioma subtypes. Neurooncol Adv. 2020 Apr 28;2(1):vdaa053.


Fürtjes S, King JA, Goeke C, Seidel M, Goschke T, Horstmann A, Ehrlich S. Automatic and Controlled Processing: Implications for Eating Behavior. Nutrients.2020 Apr 15;12(4):1097. 


Goldstein N, Kezerle Y, Gepner Y, Haim Y, Pecht T, Gazit R, Polischuk V, Liberty IF, Kirshtein B, Shaco-Levy R, Blüher M, Rudich A. Higher Mast Cell Accumulation in Human Adipose Tissues Defines Clinically Favorable Obesity Sub-Phenotypes. Cells . 2020 Jun 20;9(6):E1508. 

Haange SB, Jehmlich N, Krügel U, Hintschich C, Wehrmann D, Hankir M, Seyfried F, Froment J, Hübschmann T, Müller S, Wissenbach DK, Kang K, Buettner C, Panagiotou G, Noll M, Rolle-Kampczyk U, Fenske W, von Bergen M. Gastric bypass surgery in a rat model alters the community structure and functional composition of the intestinal microbiota independently of weight loss. Microbiome. 2020 Feb 7;8(1):13.  


Hanke S, Tindall CA, Pippel J, Ulbricht D, Pirotte B, Reboud-Ravaux M, Heiker JT, Sträter N. Structural Studies on the Inhibitory Binding Mode of Aromatic Coumarinic Esters to Human Kallikrein-Related Peptidase 7. J Med Chem 2020 June 11;63(11):5723-5733.


Hankir MK. A sympathetic gut connection drives the metabolic benefits of Roux-en-Y gastric bypass. Cell Stress. 2020 Nov 24;4(12):265-269


Hartmann H, Pauli KL, Janssen KL, Huhn S, Ceglarek U, Horstmann A. Preliminary evidence for an association between intake of high‐fat high‐sugar diet, variations in peripheral dopamine precursor availability and dopamine‐dependent cognition in humans. J Neuroendocrinol. 2020 Nov 3:e12917. 


Hauffe R, Stein V, Chudoba C, Flore T, Rath M, Ritter K, Schell M, Wardelmann K, Deubel S, Kopp JF, Schwarz M, Kappert K, Blüher M, Schwerdtle T, Kipp AP, Kleinridders A. GPx3 Dysregulation Impacts Adipose Tissue Insulin Receptor Expression and Sensitivity. JCI Insight. 2020 June 4;5 (11); 63(11):136283


Hirschel J, Vogel M, Baber R, Garten A, Beuchel C, Dietz Y, Dittrich J, Körner A, Kiess W, Ceglarek U. Relation of Whole Blood Amino Acid and Acylcarnitine Metabolome to Age, Sex, BMI, Puberty, and Metabolic Markers in Children and Adolescents. Metabolites. 2020 Apr 10;10(4). 


Höring M, Ekroos K, Baker PRS, Connell L, Stadler SC, Burkhardt R, Liebisch G. Correction of isobaric overlap resulting from sodiated ions in lipidomics. Anal Chem. 2020 Jul 16.


Hoser SM, Hoffmann A, Meindl A, Gamper M, Fallmann J, Bernhart SH, Müller L, Ploner M, Misslinger M, Kremser L, Lindner H, Geley S, Schaal H, Stadler PF, Huettenhofer A. Intronic tRNAs of mitochondrial origin regulate constitutive and alternative splicing. Genome Biol. 2020 Dec 8;21(1):299.


Jacobi T, Massier L, Klöting N, Horn K, Schuch A, Ahnert P, Engel C, Löffler M, Burkhardt R, Thiery J, Tönjes A, Stumvoll M, Blüher M, Doxiadis I, Scholz M, Kovacs P. HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non–Insulin-Treated Type 2 Diabetes. J Clin Endocrinol Metab. 2020 Mar 1;105(3).


Jacobson KA, Delicado EG, Gachet C, Kennedy C, von Kügelgen I, Li B, Miras-Portugal MT, Novak I, Schöneberg T, Perez-Sen R, Thor D, Wu B, Yang Z, Müller CE. Update of P2Y Receptor Pharmacology: IUPHAR Review:27. Br J Pharmacol. 2020 Feb 9.


Jäger E, Murthy S, Schmidt C, Hahn M, Strobel S, Peters A, Stäubert C, Sungur P, Venus T, Geisler M, Radusheva V, Raps S, Rothe K, Scholz R, Jung S, Wagner S, Pierer M, Seifert O, Chang W, Estrela-Lopis I, Raulien N, Krohn K, Sträter N, Hoeppener S, Schöneberg T, Rossol M, Wagner U. Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis. Nat Commun. 2020 Aug 25;11(1):4243.


Janssen LK, Mahner FP, Schlagenhauf F, Deserno L, Horstmann A. Reliance on model-based and model-free control in obesity. Sci Rep. 2020 Dec 31;10(1):22433.


Kaiser A, Wanka L, Ziffert I, Beck-Sickinger AG. Biased agonists at the human Y1 receptor lead to prolonged membrane residency and extended receptor G protein interaction. Cell Mol Life Sci. 2020 Jan 9.


Kalkhof S, Krieg L, Büttner P, Wabitsch M, Küntzel C, Friebe D, Landgraf K, Hanschkow M, Schubert K, Kiess W, Krohn K, Blüher M, von Bergen M, Körner AIn Depth Quantitative Proteomic and Transcriptomic Characterization of Human Adipocyte Differentiation Using the SGBS Cell Line. Proteomics.2020 May 8; e1900405.


Kässner F, Kirstein A, Händel N, Schmid GL, Landgraf K, Berthold A, Tannert A, Schaefer M, Wabitsch M, Kiess W, Körner A, Garten A. A New Human Adipocyte Model With PTEN Haploinsufficiency. Adipocyte. 2020 Dec;9(1):290-301.


Keller M, Gebhardt C, Huth S, Schleinitz D, Heyne H, Scholz M, Stumvoll M, Böttcher Y, Tönjes A, Kovacs P. Genetically programmed changes in transcription of the novel progranulin regulator. J Mol Med (Berl) . 2020 Jul 3.


Keller M, Yaskolka Meir A, Bernhart SH, Gepner Y, Shelef I, Schwarzfuchs D, Tsaban G, Zelicha H, Hopp L, Müller L, Rohde K, Böttcher Y, Stadler PF, Stumvoll M, Blüher M, Kovacs P, Shai I. DNA methylation signature in blood mirrors successful weight-loss during lifestyle interventions: the CENTRAL trial. Genome Med. 2020 Nov 16;12(1):97.


Klöting N, Kern M, Moruzzi M, Stumvoll M, Blüher M. Tamoxifen treatment causes early hepatic insulin resistance. Acta Diabetol. 2020 Jan 6.


Klöting N, Ristow M, Blüher M. Effects of exercise on ACE2. Obesity (Silver Spring). 2020 Sep 17.


Kralisch S, Hoffmann A, Estrada-Kunz J, Stumvoll M, Fasshauer M, Tönjes A, Miehle K. Increased Growth Differentiation Factor 15 in Patients with Hypoleptinemia-Associated Lipodystrophy. Int J Mol Sci. 2020 Sep 29;21(19):E7214. 


Krieg L, Schaffert A, Kern M, Landgraf K, Wabitsch M, Beck-Sickinger AG, Koerner A, Blüher M, von Bergen M, Schubert K. An MRM-Based Multiplexed Quantification Assay for Human Adipokines and Apolipoproteins. Molecules. 2020 Feb 11;25(4). pii: E775.


Kube J, Wiencke K, Hahn S, Villringer A, Neumann J. Enhanced Go and NoGo Learning in Individuals With Obesity. Front Behav Neurosci. 2020 Feb 14;14:15.


Kunath A, Heiker JT, Kern M, Kosacka J, Flehmig G, Stumvoll M, Kovacs P, Blüher M, Klöting N. Nicotinamide Nucleotide Transhydrogenase (Nnt) Is Related to Obesity in Mice.  Horm Metab Res . 2020 Jul 6.


Kulow C, Reske A, Leimert M, Bechmann I, Winter K, Steinke H. Topography and evidence of a separate "fascia plate" for the femoral nerve inside the iliopsoas - A dorsal approach. J Anat. 2020 Dec 25.


Kynast J, Quinque EM, Polyakova M, Luck T, Riedel-Heller SG, Baron-Cohen S, Hinz A, Witte AV, Sacher J, Villringer A, Schroeter ML. Mindreading From the Eyes Declines With Aging - Evidence From 1,603 Subjects. Front Aging Neurosci. 2020 Oct 22;12:550416.


Landgraf K, Klöting N, Gericke M, Maixner N, Guiu-Jurado E, Scholz M, Witte AV, Beyer F, Schwartze JT, Lacher M, Villringer A, Kovacs P, Rudich A, Blüher M, Kiess W, Körner A.The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG.Cell Rep. 2020 Oct 20;33(3):108295.


Le Duc D, Lin CC, Popkova Y, Yang Z, Akhil V, Çakir MV, Grunewald S, Simon JC, Dietz A, Dannenberger D, Garten A, Lemke JR, Schiller J, Blüher M, Nono Nankam PA, Rolle-Kampczyk U, von Bergen M, Kelso J, Schöneberg T. Reduced lipolysis in lipoma phenocopies lipid accumulation in obesity. Int J Obes (Lond). 2020 Nov 24.


Leppert B, Strunz S, Seiwert B, Schlittenbauer L, Schlichting R, Pfeiffer C, Röder S, Bauer M, Borte M, Stangl GI, Schöneberg T, Schulz A, Karkossa I, Rolle-Kampczyk UE, Thürmann L, von Bergen M, Escher BI, Junge KM, Reemtsma T, Lehmann I, Polte T. Maternal paraben exposure triggers childhood overweight development. Nat Commun. 2020 Feb 11;11(1):561.


Levakov G, Kaplan A, Yaskolka Meir A, Rinott E, Tsaban G, Zelicha H, Meiran N, Shelef I, Shai I, Avidan G. Neural correlates of future weight loss reveal a possible role for brain-gastric interactions. Neuroimage. 2020 Sep 23;224:117403.


Lindhorst A, Bechmann I, Gericke M. Unspecific DNA recombination in AdipoqCre-ERT2 – mediated knockout approaches in transgenic mice is sex-, age- and genotype-dependent. Adipocyte. 2020 Dec;9(1):1-6.


Lorenz R, Stadler PF. RNA Secondary Structures with Limited Base Pair Span: Exact Backtracking and an Application. Genes (Basel). 2020 Dec 24;12(1):E14.


Maixner N, Pecht T, Haim Y, Chalifa-Caspi V, Goldstein N, Tarnovscki T, Liberty IF, Kirshtein B, Golan R, Berner O, Monsonego A, Bashan N, Blüher M, Rudich A. A TRAIL-TL1A Paracrine Network Involving Adipocytes, Macrophages and lymphocytes Induces Adipose Tissue Dysfunction Downstream of E2F1 in Human Obesity. Diabetes. 2020 Jul 30;db191231.


Massier L, Chakaroun R, Tabei S, Crane A, Didt KD, Fallmann J, von Bergen M, Haange SB, Heyne H, Stumvoll M, Gericke M, Dietrich A, Blüher M, Musat N, Kovacs P. Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 Diabetes. Gut. 2020 Apr 21. pii: gutjnl-2019-320118.


Massier L, Chakaroun R, Kovacs P, Heiker JT. Blurring the picture in leaky gut research: how shortcomings of zonulin as a biomarker mislead the field of intestinal permeability. Gut . 2020 Oct 9;gutjnl-2020-323026.


Mattar P, Sanhueza S, Yuri G, Briones L, Perez-Leighton C, Rudich A, Lavandero S, Cifuentes M. Calcium-Sensing Receptor in Adipose Tissue: Possible Association with Obesity-Related Elevated Autophagy. Int J Mol Sci. 2020 Oct 15;21(20):7617.


Medawar E, Enzenbach C, Roehr S, Villringer A, Riedel-Heller SG, Witte AV. Less Animal-based Food, Better Weight Status: Associations of the Restriction of Animal-Based Product Intake With Body-Mass-Index, Drepressive Symptoms and Personality in the Gerneral Population. Nutrients. 2020 May 20; 12(5):E1492.

Molinaro A, Bel Lassen P, Henricsson M, Wu H, Adriouch S, Belda E, Chakaroun R, Nielsen T, Bergh PO, Rouault C, André S, Marquet F, Andreelli F, Salem JE, Assmann K, Bastard JP, Forslund S, Le Chatelier E, Falony G, Pons N, Prifti E, Quinquis B, Roume H, Vieira-Silva S, Hansen TH, Pedersen HK, Lewinter C, Sønderskov NB; MetaCardis Consortium, Køber L, Vestergaard H, Hansen T, Zucker JD, Galan P, Dumas ME, Raes J, Oppert JM, Letunic I, Nielsen J, Bork P, Ehrlich SD, Stumvoll M, Pedersen O, Aron-Wisnewsky J, Clément K, Bäckhed F. Author Correction: Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology. Nat Commun. 2020 Dec 21;11(1):6448.
 

Morys F, Janssen LK, Cesnaite E, Beyer F, Garcia-Garcia I, Kube J, Kumral D, Liem F, Mehl N, Mahjoory K, Schrimpf A, Gaebler M, Margulies D, Villringer A, Neumann J, Nikulin VV, Horstmann A. Hemispheric asymmetries in resting‐state EEG and fMRI are related to approach and avoidance behaviour, but not to eating behaviour or BMI. Hum Brain Mapp. 2020;41:1136-1152.
 

Mulhem A, Moulla Y, Klöting N, Ebert T, Tönjes A, Fasshauer M, Dietrich A, Schön MR, Stumvoll M, Richter V, Blüher M. Circulating cell adhesion molecules in metabolically healthy obesity.Int J Obes (Lond).Int J Obes (Lond). 2020 Sep 1.


Nono Nankam PA, Blüher M, Kehr S, Klöting N, Krohn K, Adams K, Stadler PF, Mendham AE, Goedecke JH. Distinct abdominal and gluteal
adipose tissue transcriptome signatures are altered by exercise training in African women with obesity. Sci Rep. 2020 Jun 24;10(1):10240.


Orsó E, Burkhardt R. ATP-citrate lyase: a driver of metabolism and histone acetylation. Curr Opin Lipidol. 2020 Dec;31(6):362-363.


Peters A, Rabe P, Krumbholz P, Kalwa H, Kraft R, Schöneberg T, Stäubert C. Natural biased signaling of hydroxycarboxylic acid receptor 3 and G protein-coupled receptor 84. Cell Commun Signal. 2020 Feb 26;18(1):31.


Piotrowska A, Winter K, Carare RO, Bechmann I. Vital Functions Contribute to the Spread of Extracellular Fluids in the Brain: Comparison Between Life and Death. Front Aging Neurosci. 2020 Feb 11;12:15


Poessel M, Breuer N, Joshi A, Pampel A, Villringer A, Hummel T, Horstman A. Reduced Olfactory Bulb Volume in Obesity and Its Relation to Metabolic Health Status. Front. Hum. Neurosci. 2020 Nov 27;14:586998.


Poessel M, Freiherr J, Wiencke K, Villringer A, Horstmann A. Insulin Resistance Is Associated with Reduced Food Odor Sensitivity across a Wide Range of Body Weights. Nutrients. 2020 Jul 24;12(8):E2201.


Rohde K, Rønningen T, la Cour Poulsen L, Keller M, Blüher M, Böttcher Y. Role of the DNA repair genes H2AX and HMGB1 in human fat distribution and lipid profiles. BMJ Open Diabetes Res Care. 2020 Feb;8(1).


Rolle-Kampczyk U, Gebauer S, Haange SB, Schubert K, Kern M, Moulla Y, Dietrich A, Schön MR, Klöting N, von Bergen MBlüher M. Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation. Sci Total Environ. 2020 Dec 15;748:142458.


Röthe J, Kraft R, Schöneberg T, Thor D. Exploring G Protein-Coupled Receptor Signaling in Primary Pancreatic Islets. Biol Proced Online. 2020 Feb 15;22:4.


Ruiz-Ojeda FJ, Wang J, Bäcker T, Krueger M, Zamani S, Rosowski S, Gruber T, Onogi Y, Feuchtinger A, Schulz TJ, Fässler R, Müller TD, García-Cáceres C, Meier M, Blüher M, Ussar S. Active integrins regulate white adipose tissue insulin sensitivity and brown fat thermogenesis. Mol Metab. 2020 Dec 21:101147.


Schleinitz D, Krause K, Wohland T, Gebhardt C, Linder N, Stumvoll M, Blüher M, Bechmann I, Kovacs P, Gericke M, Tönjes A. Identification of distinct transcriptome signatures of human adipose tissue from fifteen depots. Eur J Hum Genet. 2020 Jul 13.


Schopow N, Kallendrusch S, Gong S, Rapp F, Körfer J, Gericke M, Spindler N, Josten C, Langer S, Bechmann I. Examination of Ex-Vivo Viability of Human Adipose Tissue Slice Culture. PLoS One. 2020 May 26; 15(5):e0233152.


Sela I, Yaskolka Meir A, Brandis A, Krajmalnik-Brown R, Zeibich L, Chang D, Dirks B, Tsaban G, Kaplan A, Rinott E, Zelicha H, Arinos S, Ceglarek U, Isermann B, Lapidot M, Green R, Shai I. Wolffia globosa-Mankai Plant-Based Protein Contains Bioactive Vitamin B 12 and Is Well Absorbed in Humans. Nutrients . 2020 Oct 8;12(10):3067.


Streidl T, Karkossa I, Segura Muñoz RR, Eberl C, Zaufel A, Plagge J, Schmaltz R, Schubert K, Basic M, Schneider KM, Afify M, Trautwein C, Tolba R, Stecher B, Doden HL, Ridlon JM, Ecker J, Moustafa T, von Bergen M, Ramer-Tait AE, Clavel T. The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice. Gut Microbes. 2021 Jan-Dec;13(1):1-21. 


Streit WJ, Khoshbouei H, Bechmann I. Dystrophic microglia in late-onset Alzheimer's disease. Glia. 2020 Apr;68(4):845-854.


Suchý T, Zieschang C, Popkova Y, Kaczmarek I, Weiner J, Liebing AD, Çakir MV, Landgraf K, Gericke M, Pospisilik JA, Körner A, Heiker JT, Dannenberger D, Schiller J, Schöneberg T, Liebscher I, Thor D. The repertoire of Adhesion G protein-coupled receptors in adipocytes and their functional relevance. Int J Obes (Lond). 2020 Mar 19. 


Sun C, Kovacs P, Guiu-Jurado E. Genetics of Obesity in East Asians.  Front Genet. 2020 Oct 20;11:575049.


Tindall CA, Dommel S, Riedl V, Ulbricht D, Hanke S, Sträter N, Heiker JT. Membrane Phospholipids and Polyphosphates as Cofactors and Binding Molecules of SERPINA12 (vaspin). Molecules. 2020 Apr 24;25(8). pii: E1992. 


Voigtmann F, Wolf P, Landgraf K, Stein R, Kratzsch J, Schmitz S, Jamra RA, Blüher M, Meiler J, Beck-Sickinger AG, Kiess W, Körner A. Identification of a novel leptin receptor (LEPR) variant and proof of functional relevance directing treatment decisions in patients with morbid obesity. Metabolism. 2020 Nov 19:154438


Wiencke K, Horstmann A, Mathar D, Villringer A, Neumann J. Dopamine release, diffusion and uptake: A computational model for synaptic and volume transmission. PLoS Comput Biol 2020;16(11):e1008410.


Wittrisch S, Klöting N, Mörl K, Chakaroun R, Blüher M, Beck-Sickinger AG. NPY1R-targeted peptide-mediated delivery of a dual PPARα/γ agonist to adipocytes enhances adipogenesis and prevents diabetes Progression. Mol Metab. 2020 Jan;31:163-180.


Zacharia A, Saidemberg D, Mannully CT, Kogan NM, Shehadeh A, Sinai R, Zucker A, Bruck-Haimson R, Goldstein N, Haim Y, Dani C, Rudich A, Moussaieff A. Distinct infrastructure of lipid networks in visceral and subcutaneous adipose tissues in overweight humans. Am J Clin Nutr. 2020 Aug 7;nqaa195.


Zhao S, Todorov MI, Cai R, -Maskari RA, Steinke H, Kemter E, Mai H, Rong Z, Warmer M, Stanic K, Schoppe O, Paetzold JC, Gesierich B, Wong MN, Huber TB, Duering M, Bruns OT, Menze B, Lipfert J, Puelles VG, Wolf E, Bechmann I, Ertürk A. Cellular and Molecular Probing of Intact Human Organs. Cell. 2020 Feb 20;180(4):796-812.e19.


Ziffert I, Kaiser A, Babilon S, Mörl K, Beck-Sickinger AG. Unusually persistent Gαi-signaling of the neuropeptide Y2 receptor depletes cellular Gi/o pools and leads to a Gi-refractory state. Cell Commun Signal. 2020 Mar 30;18(1):49.


Ziffert I, Kaiser A, Hoppenz P, Mörl K, Beck-Sickinger AG. Shuttling of Peptide-Drug Conjugates by G Protein-coupled Receptors is Significantly Improved by Pulsed Application. ChemMedChem. 2020 Jul 22.

2019

Abshagen K, Mense L, Fischer F, Liebig M, Schaeper U, Navarro G, Glass Ä, Frank M, Klöting N, Vollmar B. Repin1 deficiency in liver tissue alleviates NAFLD progression in mice. J Adv Res. 2018 Nov 22;16:99-111.


Beuchel C, Becker S, Dittrich J, Kirsten H, Toenjes A, Stumvoll M, Loeffler M, Thiele H, Beutner F, Thiery J, Ceglarek U, Scholz M., Clinical and lifestyle related factors influencing whole blood metabolite levels - A comparative analysis of three large cohorts. Mol Metab. 2019 Nov;29:76-85.


Beyer F, García-García I, Heinrich M, Schroeter ML, Sacher J, Luck T, Riedel-Heller SG, Stumvoll M, Villringer A, Witte AV. Neuroanatomical correlates of food addiction symptoms and body mass index in the general population. Hum Brain Mapp. 2019 Feb 28.


Beyer F, Kharabian Masouleh S, Kratzsch J, Schroeter ML, Röhr S, Riedel-Heller SG, Villringer A, Witte AV. A Metabolic Obesity Profile Is Associated With Decreased Gray Matter Volume in Cognitively Healthy Older Adults. Front Aging Neurosci. 2019 Aug 2;11:202.


Blücher C, Zilberfain C, Venus T, Spindler N, Dietrich A, Burkhardt R, Stadler SC, Estrela-Lopis I. Single cell study of adipose tissue mediated lipid droplet formation and biochemical alterations in breast cancer cells. Analyst. 2019 Aug 13


Blüher M. Obesity: global epidemiology and pathogenesis. Nat Rev Endocrinol. 2019 Feb 27.


Blüher M., Neuregulin 4: A "Hotline" Between Brown Fat and Liver., Obesity (Silver Spring). 2019 Oct;27(10):1555-1557 


Bradley EC, Cunningham RL, Wilde C, Morgan RK, Klug EA, Letcher SM, Schöneberg T, Monk KR, Liebscher I, Petersen SC. In vivo identification of small molecules mediating Gpr126/Adgrg6 signaling during Schwann cell development., Ann N Y Acad Sci. 2019 Sep 16.


Breitfeld J, Wiele N, Gutsmann B, Stumvoll M, Blüher M, Scholz M, Kovacs P, Tönjes A. Circulating Adipokine VASPIN Is Associated with Serum Lipid Profiles in Humans. Lipids. 2019 Mar 18.


Eichler W, Lohrenz A, Simon KU, Krohn S, Lange J, Bürger S, Liebscher I. The role of ADGRE5/CD97 in human retinal pigment epithelial cell growth and survival. Ann N Y Acad Sci. 2019 Aug 9.


Friedrich K, Sommer M, Strobel S, Thrum S, Blüher M, Wagner U, Rossol M. Perturbation of the Monocyte Compartment in Human Obesity. Front Immunol. 2019 Aug 8;10:1874. 


Fromm SP, Horstmann A., Psychometric Evaluation of the German Version of the Dietary Fat and Free Sugar-Short Questionnaire. Obes Facts. 2019;12(5):518-528.


García-Cáceres C, Balland E, Prevot V, Luquet S, Woods SC, Koch M, Horvath TL, Yi CX, Chowen JA, Verkhratsky A, Araque A, Bechmann I, Tschöp MH. Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism. Nat Neurosci. 2019 Jan;22(1):7-14.


García-García I, Kube J, Morys F, Schrimpf A, Kanaan AS, Gaebler M, Villringer A, Dagher A, Horstmann A, Neumann J. Liking and left amygdala activity during food versus non-food processing are modulated by emotional context. Cogn Affect Behav Neurosci. 2019 Nov 11.


Garten A, Grohmann T, Kluckova K, Lavery GG, Kiess W, Penke M. Sorafenib-Induced Apoptosis in Hepatocellular Carcinoma Is Reversed by SIRT1. Int J Mol Sci. 2019 Aug 19;20(16). pii: E4048.


Gepner Y, Shelef I, Komy O, Cohen N, Schwarzfuchs D, Bril N, Rein M, Serfaty D, Kenigsbuch S, Zelicha H, Yaskolka Meir A, Tene L, Bilitzky A, Tsaban G, Chassidim Y, Sarusy B, Ceglarek U, Thiery J, Stumvoll M, Blüher M, Stampfer MJ, Rudich A, Shai I. The beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat Content. EBioMedicine. 2019 May 29. pii: S2352-3964(19)30358-5.


Goldstein N, Haim Y, Mattar P, Hadadi-Bechor S, Maixner N, Kovacs P, Blüher M, Rudich A. Leptin stimulates autophagy/lysosome-related degradation of long-lived proteins in adipocytes. Adipocyte. 2019 Jan 24.


Hadadi-Bechor S, Haim Y, Pecht T, Gat R, Tarnovsky T, Gericke M, Rudich A, Autophagy differentially regulates macrophage lipid handling depending on the lipid substrate (oleic acid vs. acetylated-LDL) and inflammatory activation state., Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Sep 11:158527


Hankir MK, Rullmann M, Seyfried F, Preusser S, Poppitz S, Heba S, Gousias K, Hoyer J, Schütz T, Dietrich A, Müller K, Pleger B. Roux-en-Y gastric bypass surgery progressively alters radiologic measures of hypothalamic inflammation in obese patients. JCI Insight. 2019 Aug 29. pii: 131329.


Heinitz S, Gebhardt C, Piaggi P, Krüger J, Heyne H, Weiner J, Heiker JT, Stumvoll M, Blüher M, Baier L, Rudich A, Kovacs P, Tönjes A. Atg7-knockdown reduces chemerin secretion in murine adipocytes. J Clin Endocrinol Metab. 2019 Jun 21. pii: jc.2018-01980.


van den Heuvel MP, Scholtens LH, van der Burgh HK, Agosta F, Alloza C, Arango C, Auyeung B, Baron-Cohen S, Basaia S, Benders MJNL, Beyer F, Booij L, Braun KPJ, Filho GB, Cahn W, Cannon DM, Chaim-Avancini TM, Chan SSM, Chen EYH, Crespo-Facorro B, Crone EA, Dannlowski U, de Zwarte SMC, Dietsche B, Donohoe G, Plessis SD, Durston S, Díaz-Caneja CM, Díaz-Zuluaga AM, Emsley R, Filippi M, Frodl T, Gorges M, Graff B, Grotegerd D, Gąsecki D, Hall JM, Holleran L, Holt R, Hopman HJ, Jansen A, Janssen J, Jodzio K, Jäncke L, Kaleda VG, Kassubek J, Masouleh SK, Kircher T, Koevoets MGJC, Kostic VS, Krug A, Lawrie SM, Lebedeva IS, Lee EHM, Lett TA, Lewis SJG, Liem F, Lombardo MV, Lopez-Jaramillo C, Margulies DS, Markett S, Marques P, Martínez-Zalacaín I, McDonald C, McIntosh AM, McPhilemy G, Meinert SL, Menchón JM, Montag C, Moreira PS, Morgado P, Mothersill DO, Mérillat S, Müller HP, Nabulsi L, Najt P, Narkiewicz K, Naumczyk P, Oranje B, Ortiz-Garcia de la Foz V, Peper JS, Pineda JA, Rasser PE, Redlich R, Repple J, Reuter M, Rosa PGP, Ruigrok ANV, Sabisz A, Schall U, Seedat S, Serpa MH, Skouras S, Soriano-Mas C, Sousa N, Szurowska E, Tomyshev AS, Tordesillas-Gutierrez D, Valk SL, van den Berg LH, van Erp TGM, van Haren NEM, van Leeuwen JMC, Villringer A, Vinkers CH, Vollmar C, Waller L, Walter H, Whalley HC, Witkowska M, Witte AV, Zanetti MV, Zhang R, de Lange SC. 10Kin1day: A Bottom-Up Neuroimaging Initiative. Front Neurol. 2019 May 9;10:425.


Hoppenz P, Els-Heindl S, Kellert M, Kuhnert R, Saretz S, Lerchen HG, Köbberling J, Riedl B, Hey-Hawkins E, Beck-Sickinger AG. A Selective Carborane-Functionalized Gastrin-Releasing Peptide Receptor Agonist as Boron Delivery Agent for Boron Neutron Capture Therapy. J Org Chem. 2019 Dec 23.


Hoppenz P, Els-Heindl S, Beck-Sickinger AG. Identification and stabilization of a highly selective gastrin-releasing peptide receptor agonist. J Pept Sci. 2019 Nov 19:e3224. Epub ahead of print


Janssen LK, Herzog N, Waltmann M, Breuer N, Wiencke K, Rausch F, Hartmann H, Poessel M, Horstmann A. Lost in Translation? On the Need for Convergence in Animal and Human Studies on the Role of Dopamine in Diet-Induced Obesity. Curr Addict Rep (2019) 6: 229.


Janssen LK, Mahner FP, Schlangenhauf F, Deserno L, Horstmann A. Reliance on model-based and model-free control in obesity. Jul 17,2019.


Joost E, Jordão MJC, Mages B, Prinz M, Bechmann I, Krueger M. Microglia contribute to the glia limitans around arteries, capillaries and veins under physiological conditions, in a model of neuroinflammation and in human brain tissue. Brain Struct Funct. 2019 Jan 31.


Kellert M, Hoppenz P, Lönnecke P, Worm DJ, Riedl B, Koebberling J, Beck-Sickinger AG, Hey-Hawkins E. Tuning a modular system - synthesis and characterisation of a boron-rich s-triazine-based carboxylic acid and amine bearing a galactopyranosyl moiety. Dalton Trans. 2019 Dec 6. 


Kirstein A, Augustin A, Penke M, Cea M, Körner A, Kies W, Garten A.The Novel Phosphatidylinositol-3-Kinase (PI3K) Inhibitor Alpelisib Effectively Inhibits Growth of PTEN-Haploinsufficient Lipoma Cells. Cancers (Basel). 2019 Oct 17;11(10)


Klöting N, Kern M, Moruzzi M, Stumvoll M, Blüher M. Tamoxifen treatment causes early hepatic insulin resistance. Acta Diabetol. 2020 Jan 6.


Knierim AB, Röthe J, Çakir MV, Lede V, Wilde C, Liebscher I, Thor D, Schöneberg T. Genetic basis of functional variability in adhesion G protein-coupled receptors. Sci Rep. 2019 Jul 30;9(1):11036


Kögler LM, Stichel J, Kaiser A, Beck-Sickinger AG. Cell-Free Expression and Photo-Crosslinking of the Human Neuropeptide Y2 Receptor. Front Pharmacol. 2019 Mar 1;10:176.


Kosacka J, Woidt K, Toyka KV, Paeschke S, Klöting N, Bechmann I, Blüher M, Thiery J, Ossmann S, Baum P, Nowicki M. The role of dietary non-heme iron load and peripheral nerve inflammation in the development of peripheral neuropathy (PN) in obese non-diabetic leptin-deficient ob/ob mice. Neurol Res. 2019 Jan 13:1-13.


Lammert, M., Morys, F., Hartmann, H., Janssen, L., & Horstmann, A. MIS – a new scoring method for the operation span task that accounts for math, remembered items and sequence. PsyArXiv.Aug2019


Lampe L, Zhang R, Beyer F, Huhn S, Kharabian Masouleh S, Preusser S, Bazin PL, Schroeter ML, Villringer A, Witte AV. Visceral obesity relates to deep white matter hyperintensities via inflammation. Ann Neurol. 2019 Feb;85(2):194-203.


Lindhorst A, Bechmann I, Gericke M. Unspecific DNA recombination in AdipoqCre-ERT2 - mediated knockout approaches in transgenic mice is sex-, age- and genotype-dependent. Adipocyte. 2020 Dec;9(1):1-6.


Mancini G, Pirruccio K, Yang X, Blüher M, Rodeheffer M, Horvath TL., Mitofusin 2 in Mature Adipocytes Controls Adiposity and Body Weight. Cell Rep. 2019 Mar 12;26(11):2849-2858.e4.


Mandić AD, Woting A, Jaenicke T, Sander A, Sabrowski W, Rolle-Kampcyk U, von Bergen M, Blaut M. Clostridium ramosum regulates enterochromaffin cell development and serotonin release. Sci Rep. 2019 Feb 4;9(1):1177.


Medawar E, Huhn S, Villringer A, Witte A., The effects of plant-based diets on the body and the brain: a systematic Review., Transl Psychiatry. 2019 Sep 12;9(1):226.


Meemken MT, Horstmann A. Appetitive Pavlovian-to-Instrumental Transfer in Participants with Normal-Weight and Obesity. Nutrients. 2019 May 9;11(5). pii: E1037.


Mehl N, Morys F, Villringer A, Horstmann A. Unhealthy yet Avoidable-How Cognitive Bias Modification Alters Behavioral and Brain Responses to Food Cues in Individuals with Obesity. Nutrients. 2019 Apr 18;11(4).


Miletić Vukajlović J, Drakulić D, Pejić S, Ilić TV, Stefanović A, Petković M, Schiller J., INCREASED PLASMA PHOSPHATIDYLCHOLINE / LYSOPHOSPHATIDYLCHOLINE RATIOS IN PATIENTS WITH PARKINSON'S DISEASE. Rapid Commun Mass Spectrom. 2019 Sep 13.


Peters A, Krumbholz P, Jäger E, Heintz-Buschart A, Çakir MV, Rothemund S, Gaudl A, Ceglarek U, Schöneberg T, Stäubert C. Metabolites of lactic acid bacteria present in fermented foods are highly potent agonists of human hydroxycarboxylic acid receptor 3. PLoS Genet. 2019 May 23;15(5):e1008145.


Poessel M, Freiherr J, Horstmann A. Rapid assessment of olfactory sensitivity using the “Sniffin’ Sticks. Springer 2019.


Popkova Y, Dannenberger D, Schiller J, Engel KM. Differences in the lipid patterns during maturation of 3T3-L1 adipocytes investigated by thin-layer chromatography, gas chromatography, and mass spectrometric approaches. Anal Bioanal Chem. 2019 Dec 3.


Püschel J, Miehle K, Müller K, Villringer A, Stumvoll M, Fasshauer M, Schlögl H. Beneficial effects of leptin substitution on impaired eating behavior in lipodystrophy are sustained beyond 150 weeks of treatment. Cytokine. 2019 Jan;113:400-404.


Reinicke M, Dorow J, Bischof K, Leyh J, Bechmann I, Ceglarek U. Tissue pretreatment for LC-MS/MS analysis of PUFA and eicosanoid distribution in mouse brain and liver. Anal Bioanal Chem. 2019 Dec 21.


Rohde K, Keller M, la Cour Poulsen L, Rønningen T, Stumvoll M, Tönjes A, Kovacs P, Horstmann A, Villringer A, Blüher M, Böttcher Y. (Epi)genetic regulation of CRTC1 in human eating behaviour and fat Distribution. EBioMedicine.2019Jun;44:476-488.


Röthe J, Thor D, Winkler J, Knierim AB, Binder C, Huth S, Kraft R, Rothemund S, Schöneberg T, Prömel S. Involvement of the Adhesion GPCRs Latrophilins in the Regulation of Insulin Release. Cell Rep. 2019 Feb 5;26(6):1573-1584.


Rullmann M, Preusser S, Poppitz S, Heba S, Gousias K, Hoyer J, Schütz T, Dietrich A, Müller K, Hankir MK, Pleger B., Adiposity Related Brain Plasticity Induced by Bariatric Surgery., Front Hum Neurosci. 2019 Aug 27;13:290.


Satizabal C., [...], Witte AV, [...], Villringer A, [...], Seshadri S., Genetic Architecture of Subcortical Brain Structures in 38,851 Individuals., Nat Genet. 2019 Oct 21. Epub ahead of print


Seyfried F, Hankir MK. Could de-stressing the brain be the solution for long-term weight loss?, Cell Stress. 2019 Jan 25;3(2):29-37. 


Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, Sadlon T, Osei-Sarpong C, Subbaramaiah K, Copperi F, Haendler K, Varga T, Schanz O, Bourry S, Bassler K, Krebs W, Peters AE, Baumgart AK, Schneeweiss M, Klee K, Schmidt SV, Nüssing S, Sander J, Ohkura N, Waha A, Sparwasser T, Wunderlich FT, Förster I, Ulas T, Weighardt H, Sakaguchi S, Pfeifer A, Blüher M, Dannenberg AJ, Ferreirós N, Muglia LJ, Wickenhauser C, Barry SC, Schultze JL, Beyer M. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity. 2019 Apr 15. pii: S1074-7613(19)30131-1.


Scholz N, Langenhan T, Schöneberg T. Revisiting the classification of adhesion GPCRs. Ann N Y Acad Sci. 2019 Jul 31.


Schöneberg T, Prömel S. Latrophilins and Teneurins in Invertebrates: No Love for Each Other? Front. Neurosci., 12 March 2019


Teumer A, [...], Körner A, Kovacs P, [...], Stumvoll M, [...], Köttgen A. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria. Nat Commun. 2019 Sep 11;10(1):4130.


Thomas K, Beyer F, Lewe G, Zhang R, Schindler S, Schönknecht P, Stumvoll M, Villringer A, Witte AV. Higher body mass index is linked to altered hypothalamic microstructure. Sci Rep. 2019 Nov 22;9(1):17373.


Wagner R, Dittrich J, Thiery J, Ceglarek U, Burkhardt R. Simultaneous LC-MS/MS quantification of eight apolipoproteins in normal and hypercholesterolemic mouse plasma. J Lipid Res. 2019 Feb 5. pii: jlr.D084301


Warrington NM, [...], Kovacs P, [...], Tönjes A, Stumvoll M, Michaelsen KF, Eloranta AM, Lakka TA, van Duijn CM, Kiess W, Körner A, [...], Freathy RM. Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nat Genet. 2019 May;51(5):804-814.


Weingarten MFJ, Scholz M, Wohland T, Horn K, Stumvoll M, Kovacs P, Tönjes A. Circulating oxytocin is genetically determined and associated with obesity and impaired glucose tolerance. J Clin Endocrinol Metab. 2019 Jul 30. pii: jc.2019-00643


Wuttke M,[...] Kiess W, Kleber M, Koenig W, Kooner JS, Körner A, Kovacs P,[...] Stumvoll M., Pattaro C. A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet. 2019 Jun;51(6):957-972.


Yaskolka Meir A, Tsaban G, Zelicha H, Rinott E, Kaplan A, Youngster I, Rudich A, Shelef I, Tirosh A, Brikner D, Pupkin E, Sarusi B, Blüher M, Stumvoll M, Thiery J, Ceglarek U, Stampfer MJ, Shai I. A Green-Mediterranean Diet, Supplemented with Mankai Duckweed, Preserves Iron-Homeostasis in Humans and Is Efficient in Reversal of Anemia in Rats. J Nutr. 2019 Mar 27. pii: nxy321.


Yu H, Dilbaz S, Coßmann J, Hoang AC, Diedrich V, Herwig A, Harauma A, Hoshi Y, Moriguchi T, Landgraf K, Körner A, Lucas C, Brodesser S, Balogh L, Thuróczy J, Karemore G, Kuefner MS, Park EA, Rapp C, Travers JB, Röszer T. Breast milk alkylglycerols sustain beige adipocytes through adipose tissue macrophages. J Clin Invest. 2019 May 13;130:2485-2499.


Zelicha H, Kaplan A, Yaskolka Meir A, Tsaban G, Rinott E, Shelef I, Tirosh A, Brikner D, Pupkin E, Qi L, Thiery J, Stumvoll M, Kloting N, von Bergen M, Ceglarek U, Blüher M, Stampfer MJ, Shai I. The Effect of Wolffia globosa Mankai, a Green Aquatic Plant, on Postprandial Glycemic Response: A Randomized Crossover Controlled Trial. Diabetes Care. 2019 Jul;42(7):1162-1169


Zsido RG, Heinrich M, Slavich GM, Beyer F, Kharabian Masouleh S, Kratzsch J, Raschpichler M, Mueller K, Scharrer U, Löffler M, Schroeter ML, Stumvoll M, Villringer A, Witte AV, Sacher J. Association of Estradiol and Visceral Fat With Structural Brain Networks and Memory Performance in Adults. JAMA Netw Open. 2019 Jun 5;2(6):e196126.

2018

Abshagen K, Degenhardt B, Liebig M, Wendt A, Genz B, Schaeper U, Stumvoll M, Hofmann U, Frank M, Vollmar B, Klöting N. Liver-specific Repin1 deficiency impairs transient hepatic steatosis in liver regeneration. Sci Rep. 2018 Nov 15;8(1):16858.


Arndt L, Burkhardt R. Lipid metabolism: spotlight on modulators of lipoprotein lipase activity. Curr Opin Lipidol. 2018 Apr;29(2):164-165


Arndt L, Dokas J, Gericke M, Kutzner CE, Müller S, Jeromin F, Thiery J, Burkhardt R. Tribbles homolog 1 deficiency modulates function and polarization of murine bone marrow-derived macrophages. J Biol Chem. 2018 Jun 13. pii: jbc.RA117.000703.


Bartels MS, Scheffler L, Chakaroun R, Dietrich A, Blüher M, Stumvoll M, Tönjes A, Breitfeld J, Kovacs P. Increased circulating cell-free DNA in insulin resistance.Diabetes Metab. 2018 Jun 20.


Boura-Halfon S, Pecht T, Jung S, Rudich A. Obesity and dysregulated central and peripheral Macrophage-neuron crosstalk. Eur J Immunol. 2018 Nov 8.


Dittrich J, Beutner F, Teren A, Thiery J, Burkhardt R, Scholz M, Ceglarek U. Plasma levels of apolipoproteins C-III, A-IV, and E are independently associated with stable atherosclerotic cardiovascular disease. Atherosclerosis. 2018 Nov 9;281:17-24.


Ditz T, Schnapka-Hille L, Noack N, Dorow J, Ceglarek U, Niederwieser D, Schiller J, Fuchs B, Cross M. Phospholipase A2 products predict the hematopoietic support capacity of horse serum. Differentiation. 2018 Dec 6;105:27-32. 


Ebert T, Gebhardt C, Scholz M, Wohland T, Schleinitz D, Fasshauer M, Blüher M, Stumvoll M, Kovacs P, Tönjes A. Relationship between twelve adipocytokines and distinct components of the metabolic syndrome. JClinEndocrinol Metab. 2018: 10.1210/jc.2017-02085.


Engel K, Griesinger H, Schulz M, Schiller J.Normal Phase versus Reversed Phase TLC to monitor Oxidized Phosphatidylcholines by TLC/Mass Spectrometry. Rapid Commun Mass Spectrom. 2018 Jul 18.


Erbs S, Broniecki H, Scheuermann K, Winzer E, Adam J, Spielau U, Woitek F, Sandri M, Zimmer M, Besler C, Kiess W, Linke A, Körner A, Mangner N. Impact of Weight Reduction During Adolescence on Parameters of Cardiac Geometry and Function in Obese Children. JACC Cardiovasc Imaging. 2018 Jul 13.


Geserick M, Vogel M, Gausche R, Lipek T, Spielau U, Keller E, Pfäffle R, Kiess WKörner A. Acceleration of BMI in Early Childhood and Risk of Sustained Obesity. N Engl J Med. 2018 Oct 4;379(14):1303-1312.


Ghorpade DS, Ozcan L, Zheng Z, Nicoloro SM, Shen Y, Chen E, Blüher M, Czech MP, Tabas I.Hepatocyte-secreted DPP4 in obesity promotes adipose inflammation and insulin resistance. Nature. 2018 Mar 29;555(7698):673-677.


Giusepponi ME, Kern M, Chakaroun R, Wohland T, Kovacs P, Dietrich A, Schön MR, Krohn K, Pucci M, Polidori C, Micioni Di Bonaventura MV, Stumvoll MBlüher M, Cifani C, Klöting N. Gene expression profiling in adipose tissue of Sprague Dawley rats identifies olfactory receptor 984 as a potential obesity treatment target. Biochem Biophys Res Commun. 2018 Nov 2;505(3):801-806.


Grohmann T, Penke M, Petzold-Quinque S, Schuster S, Richter S, Kiess WGarten A. Inhibition of NAMPT sensitizes MOLT4 leukemia cells for etoposide treatment through the SIRT2-p53 pathway. Leukemia Res. 2018 Jun,69, 39–46.


Haimon Z, Volaski A, Orthgiess J, Boura-Halfon S, Varol D, Shemer A, Yona S, Zuckerman B, David E, Chappell-Maor L, Bechmann IGericke M, Ulitsky I, Jung S., Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies. Nat Immunol. 2018 May 18.


Hankir MH, Klingenspor M. Brown adipocyte glucose metabolism: a heated subject. EMBO Rep. 2018 Aug 22. pii: e46404.


Hankir MH, Seyfried F,  Miras AD, Cowley MA. Brain Feeding Circuits after Roux-en-Y Gastric Bypass.Trends Endocrinol Metab. 2018 Feb 20: S1043-2760(18)30018-3.


Hardikar S, Wallroth R, Villringer A, Ohla K. Shorter-lived neural taste representations in obese compared to lean individuals. Sci Rep. 2018 Jul 23;8(1):11027.


Hellrung L, Dietrich A, Hollmann M, Pleger B, Kalberlah C, Roggenhofer E, Villringer AHorstmann A. Intermittent compared to continuous real-time fMRI neurofeedback boosts control over amygdala activation. Neuroimage. 2018 Feb 1;166:198-208.


Herbert D, Franz S, Popkova Y, Anderegg U, Schiller J, Schwede K, Lorz A, Simon JC, Saalbach A. High fat diet exacerbates early psoriatic skin inflammation independent of obesity: Saturated fatty acids as key players. J Invest Dermatol. 2018 Mar 29.


Hoffmann A, Ebert T, Klöting N, Kolb M, Gericke M, Jeromin F, Jessnitzer B, Lössner U, Burkhardt R, Stumvoll M, Fasshauer M, Kralisch S. Leptin decreases circulating inflammatory IL-6 and MCP-1 in mice. Biofactors. 2018 Nov 29.


Hollenbach M, Klöting N, Sommerer I, Lorenz J, Heindl M, Kern M, Mössner J, Blüher M, Hoffmeister A. p8 deficiency leads to elevated pancreatic beta cell mass but does not contribute to insulin resistance in mice fed with high-fat diet. PLoS One. 2018 Jul 24


Horn H, Böhme B, Dietrich L, Koch M. Endocannabinoids in Body Weight Control. Pharmaceuticals (Basel). 2018 May 30;11(2).


Huhn S, Beyer F, Zhang R, Lampe L, Grothe J, Kratzsch J, Willenberg A, Breitfeld J, Kovacs PStumvoll M, Trampel R, Bazin PL, Villringer AWitte AV. Effects of resveratrol on glucose, memory and the hippocampus - a randomized controlled trial. Neuroimage. 2018 Mar 13;174:177-190.


Junge KM, Leppert B, Jahreis S, Wissenbach DK, Feltens R, Grützmann K, Thürmann L, Bauer T, Ishaque N, Schick M, Bewerunge-Hudler M, Röder S, Bauer M, Schulz A, Borte M, Landgraf K, Körner A, Kiess Wvon Bergen M, Stangl GI, Trump S, Eils R, Polte T, Lehmann I. MEST mediates the impact of prenatal bisphenol A exposure on long-term body weight development. Clin Epigenetics. 2018 Apr 20;10:58.


Kaplan A, Zelicha H, Tsaban G, Yaskolka Meir A, Rinott E, Kovsan J, Novack L, Thiery J, Ceglarek U, Burkhardt R, Willenberg A, Tirosh A, Cabantchik I, Stampfer MJ, Shai I. Protein bioavailability of Wolffia globosa duckweed, a novel aquatic plant, - A randomized controlled trial. Clin Nutr. 2018 Dec 11. pii: S0261-5614(18)32577-9. 


Kässner F, Sauer T, Penke M, Richter S, Landgraf K, Körner AKiess W, Händel N, Garten A. Simvastatin induces apoptosis in PTEN‑haploinsufficient lipoma cells. Int J Mol Med. 2018 Mar 14.


Keller M, Klös M, Rohde K, Krüger J, Kurze T, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll MBlüher M, Kovacs P, Böttcher Y. DNA methylation of SSPN is linked to adipose tissue distribution and glucose metabolism. FASEB J. 2018 Jun 22:fj201800528R.


Kratochvil I, Hofmann T, Rother S, Schlichting R, Moretti R, Scharnweber D, Hintze V, Escher BI, Meiler J, Kalkhof S, von Bergen M. MEHP and MEOHP but not DEHP bind productively to the peroxisome proliferator-activated receptor γ. Rapid Commun Mass Spectrom. 2018 Aug 7.


Krüger J, Berger C, Weidle K, Schleinitz D, Tönjes A, Stumvoll MBlüher M, Kovacs P, Klöting N. Metabolic effects of genetic variation in the human REPIN1 gene. Circ Genom Precis Med. 2018 May;11(5):e001992.


Kumar S, Grundeis F, Brand C, Hwang HJ, Mehnert J, Pleger B. Satiety-induced enhanced neuronal activity in the frontal operculum relates to the desire for food in the obese female brain. Exp Brain Res. 2018 Jun 22.


Lalem T, Zhang L, Scholz M, Burkhardt R, Saccheti V, Teren A, Thiery J, Devaux Y; Cardiolinc™ network (www.cardiolinc.org). Cyclin dependent kinase inhibitor 1 C is a female-specific marker of left ventricular function after acute myocardial infarction. Int J Cardiol. 2018 Jul 10. pii: S0167-5273(18)32556-7.


Lampe L, Zhang R, Beyer F, Huhn S, Kharabian-Masouleh S, Preusser S, Bazin PL, Schroeter ML, Villringer A, Witte AV. Visceral Obesity Relates to Deep White Matter Hyperintensities via Inflammation. Ann Neurol. 2018 Dec 17. 


Langhardt J, Flehmig G, Klöting N, Lehmann S, Ebert T, Kern M, Schön MR, Gärtner D, Lohmann T, Dressler M, Fasshauer M, Kovacs P, Stumvoll M, Dietrich A, Blüher M. Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity. Obes Facts. 2018;11(6):475-490.


Leopold J, Popkova Y, Engel KM, Schiller J. Visualizing phosphatidylcholine via mass spectrometry imaging: relevance to human health. Expert Rev Proteomics. 2018 Sep 21.


Leopold J, Popkova Y, Engel KM, Schiller J. Recent Developments of Useful MALDI Matrices for the Mass Spectrometric Characterization of Lipids. Biomolecules. 2018 Dec 13;8(4). 


Mehl N, Mueller-Wieland L, Mathar D, Horstmann A. Retraining automatic action tendencies in obesity.Physiol Behav. 2018 Mar 30. pii: S0031-9384(18)30154-9.


Meemken MT, Kube J, Wickner C, Horstmann A. Keeping track of promised rewards: Obesity predicts enhanced flexibility when learning from observation. Appetite. 2018 Dec 1;131:117-124.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Serum concentrations of fetuin B in lipodystrophic patients. Cytokine. 2018 Jun;106:165-168.


Morys F, Bode S, Horstmann A. Dorsolateral and medial prefrontal cortex mediate the influence of incidental priming on economic decision making in obesity. Sci Rep. 2018 Dec 4;8(1):17595.


Nickel A, Blücher C, Kadri OA, Schwagarus N, Müller S, Schaab M, Thiery J, Burkhardt R, Stadler SC. Adipocytes induce distinct gene expression profiles in mammary tumor cells and enhance inflammatory signaling in invasive breast cancer cells. Sci Rep. 2018 Jun 21;8(1):9482.


Pott J, Schlegel V, Teren A, Horn K, Kirsten H, Bluecher C, Kratzsch J, Loeffler M, Thiery J, Burkhardt R, Scholz M.Genetic Regulation of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) Plasma Levels and Its Impact on Atherosclerotic Vascular Disease Phenotypes. Circ Genom Precis Med. 2018 May;11(5):e001992.


Reinicke M, Schröter J, Müller-Klieser D, Helmschrodt C, Ceglarek U. Free oxysterols and bile acids including conjugates-Simultaneous quantification in human plasma and cerebrospinal fluid by liquid chromatography-tandem mass spectrometry. Analytica Chimica Acta, march 2018


Rodriguez FS, Schroeter ML, Arélin K, Witte AV, Baber R, Burkhardt R, Engel C, Löffler M, Thiery J, Villringer A, Luck T, Riedel-Heller SG. APOE e4-genotype and lifestyle interaction on cognitive performance: Results of the LIFE-Adult-study. Health Psychol. 2018 Feb;37(2):194-205.


Rohde K, Keller M, la Cour Poulsen L, Blüher M, Kovacs P, Böttcher Y. Genetics and epigenetics in obesity. Metabolism. 2018 Nov 3. pii: S0026-0495(18)30225-7.


Scheffler L, Crane A, Heyne H, Tönjes A, Schleinitz D, Ihling HC, Stumvoll M, Freire R, Fiorentino M, Fasano A, Kovacs P and Heiker JT. Widely Used commercial elisa. Does not Detect Precursor of haptoglobin2, but recognizes Properdin as a Potential second Member of the Zonulin Family. Front Endocrinol (Lausanne). 2018 Feb 5;9:22 .


Schmidt E, Dhaouadi I, Gaziano I, Oliverio M, Klemm P, Awazawa M, Mitterer G, Fernandez-Rebollo E, Pradas-Juni M, Wagner W, Hammerschmidt P, Loureiro R, Kiefer C, Hansmeier NR, Khani S, Bergami M, Heine M, Ntini E, Frommolt P, Zentis P, Ørom UA, Heeren J, Blüher M, Bilban M, Kornfeld JW. LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat. Nat Commun. 2018 Sep 6;9(1):3622


Schöneberg T, Meister J, Knierim AB, Schulz A. The G protein-coupled receptor GPR34 - The past 20 years of a grownup. Pharmacol Ther. 2018 Apr 22. pii: S0163-7258(18)30071-8.


Schröter J, Fülöp A, Hopf C, Schiller J. The combination of 2,5-dihydroxybenzoic acid and 2,5-dihydroxyacetophenone matrices for unequivocal assignment of phosphatidylethanolamine species in complex mixtures. Anal Bioanal Chem.2018 Mar;410(9):2437-2447.


Schwarz C, Wirth M, Gerischer L, Grittner U, Witte AV, Köbe T, Flöel A. Effects of Omega-3 Fatty Acids on Resting Cerebral Perfusion in Patients with Mild Cognitive Impairment: A Randomized Controlled Trial. J Prev Alzheimers Dis. 2018;5(1):26-30.


Sociali G, Grozio A, Caffa I, Schuster S, Becherini P, Damonte P, Sturla L, Fresia C, Passalacqua M, Mazzola F, Raffaelli N, Garten A, Kiess W, Cea M, Nencioni A, Bruzzone S. SIRT6 deacetylase activity regulates NAMPT activity and NAD(P)(H) pools in cancer cells. FASEB J. 2018 Dec 4:fj201800321R.


Spiller S, Li Y, Blüher M, Welch L, Hoffmann R. Diagnostic Accuracy of Protein Glycation Sites in Long-Term Controlled Patients with Type 2 Diabetes Mellitus and Their Prognostic Potential for Early Diagnosis. Pharmaceuticals (Basel). 2018 Apr 30;11(2)


Spiller S, Blüher M, Hoffmann R. Plasma levels of free fatty acids correlate with type 2 diabetes mellitus. Diabetes Obes Metab. 2018 Jun 25.


Streit WJ, Braak H, Del Tredici K, Leyh J, Lier J, Khoshbouei H, Eisenlöffel C, Müller W, Bechmann I. Microglial activation occurs late during preclinical Alzheimer's disease. Glia. 2018 Nov 11.


Tene L, Shelef I, Schwarzfuchs D, Gepner Y, Yaskolka Meir A, Tsaban G, Zelicha H, Bilitzky A, Komy O, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Chassidim Y, Sarusy B, Ceglarek UStumvoll MBlüher MThiery J, Stampfer MJ, Rudich AShai I. The effect of long-term weight-loss intervention strategies on the dynamics of pancreatic-fat and morphology: An MRI RCT study.Clin Nutr ESPEN. 2018 Apr;24:82-89.


Tönjes A, Scholz M, Krüger J, Krause K, Schleinitz D, Kirsten H, Gebhardt C, Marzi C, Grallert H, Ladenvall C, Heyne H, Laurila E, Kriebel J, Meisinger C, Rathmann W, Gieger C, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Fischer-Rosinsky A, Pfeiffer A, Krohn K, Spranger J, Thiery JBlüher MStumvoll MKovacs P. Genome-wide meta-analysis identifies novel determinants of circulating serum progranulin. Hum Mol Genet. 2018 Feb 1;27(3):546-558.


Ulbricht D, Tindall CA, Oertwig K, Hanke S, Sträter N, Heiker JT. Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin. Biological Chemistry  2018 Feb 1.


Vojinovic D, Adams HH, Jian X, Yang Q, Smith AV, Bis JC, Teumer A, Scholz M, Armstrong NJ, Hofer E, Saba Y, Luciano M, Bernard M, Trompet S, Yang J, Gillespie NA, van der Lee SJ, Neumann A, Ahmad S, Andreassen OA, Ames D, Amin N, Arfanakis K, Bastin ME, Becker DM, Beiser AS, Beyer F, Brodaty H, Bryan RN, Bülow R, Dale AM, De Jager PL, Deary IJ, DeCarli C, Fleischman DA, Gottesman RF, van der Grond J, Gudnason V, Harris TB, Homuth G, Knopman DS, Kwok JB, Lewis CE, Li S, Loeffler M, Lopez OL, Maillard P, El Marroun H, Mather KA, Mosley TH, Muetzel RL, Nauck M, Nyquist PA, Panizzon MS, Pausova Z, Psaty BM, Rice K, Rotter JI, Royle N, Satizabal CL, Schmidt R, Schofield PR, Schreiner PJ, Sidney S, Stott DJ, Thalamuthu A, Uitterlinden AG, Valdés Hernández MC, Vernooij MW, Wen W, White T, Witte AV, Wittfeld K, Wright MJ, Yanek LR, Tiemeier H, Kremen WS, Bennett DA, Jukema JW, Paus T, Wardlaw JM, Schmidt H, Sachdev PS, Villringer A, Grabe HJ, Longstreth WT, van Duijn CM, Launer LJ, Seshadri S, Ikram MA, Fornage M. Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume.Nat Commun. 2018 Nov 23;9(1):4960.


Vorselen D, van Dommelen SM, Sorkin R, Piontek MC, Schiller J, Döpp ST, Kooijmans SAA, van Oirschot BA, Versluijs BA, Bierings MB, van Wijk R, Schiffelers RM, Wuite GJL, Roos WH.The fluid membrane determines mechanics of erythrocyte extracellular vesicles and is softened in hereditary spherocytosis. Nat Commun. 2018 Nov 23;9(1):4960.


Wagner IV, Sahlin L, Savchuk I, Klöting N, Svechnikov K, Söder O. Adipose Tissue is a Potential Source of Hyperandrogenism in Obese Female Rats. Obesity (Silver Spring). 2018 Jul;26(7):1161-1167.


Wanka L, Babilon S, Kaiser A, Mörl K, Beck-Sickinger AG.Different mode of arrestin-3 binding at the human Y1 and Y2 receptor.Cell Signal. 2018 Jun 23. pii: S0898-6568(18)30130-X.


Weiner J, Zieger K, Pippel J, Heiker JT. Molecular mechanisms of vaspin action – from adipose tissue to skin and bone, from blood vessels to the brain. Adv Exp Med Biol. 2018 Jul 27.


Wistehube T, Rullmann M, Wiacek C, Braun P, Pleger B. Fat perception in the human frontal operculum, insular and somatosensory cortex. Sci Rep. 2018 Aug 7;8(1):11825.


Zhang R, Beyer F, Lampe L, Luck T, Riedel-Heller SG, Loeffler M, Schroeter ML, Stumvoll MVillringer A, Witte AV. White matter microstructural variability mediates the relation between obesity and cognition in healthy adults. Neuroimage. 2018 Feb 2;172:239-249.


Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B. Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor. Nature. 2018 Apr;556(7702):520-524.

https://www.ncbi.nlm.nih.gov/pubmed/29494334

2017

Bechor S, Nachmias D, Elia N, Haim Y, Vatarescu M, Leikin-Frenkel A, Gericke M, Tarnovsky T, Las G, Rudich A. Adipose tissue conditioned media support macrophage lipid-droplet biogenesis by interfering with autophagic flux. Biochim Biophys Acta. 2017;1862:1001-12.


Braune J, Weyer U, Hobusch C, Mauer J, Brüning J, Bechmann IGericke M. IL-6 regulates M2 polarization and local proliferation of adipose tissue macrophes in obesity. J Immunol. 2017;198:2927-34.


Braune J, Weyer U, Matz-Soja M, Hobusch C, Kern M, Kunath A, Klöting N, Kralisch S, Blüher M, Gebhardt R, Zavros Y, Bechmann IGericke M. Hedgehog sinaling in myeloid cells impacts on body weight, adipose tissue inflammation and glucose metabolism. Diabetologia. 2017;6:889-99.


Buerger F, Müller S, Ney N, Weiner J, Heiker JT, Kallendrusch S, Kovacs P, Schleinitz D, Thiery J, Stadler SC, Burkhardt R. Depletion of Jmjd1c impairs adipogenesis in murine 3T3-L1 cells. Biochim Biophys Acta. 2017;1863:1709-17.


Engel KM, Schiller J. A comparison of PC oxidation products as detected by MALDI-TOF and ESI-IT mass spectrometry. Chem Phys Lipids. 2017;203:33-45.


Engel KM, Schiller J, Müller K, Dannenberger D, Jakop U. The phospholipid composition of kangaroo spermatozoa verified by mass spectrometric lipid analysis. Lipids. 2017;52:857-69.


Gepner Y, Shelef I, Schwarzfuchs D, Cohen N, Bril N, Rein M, Tsaban G, Zelicha H, Yaskolka Meir A, Tene L, Sarusy B, Rosen P, Hoffman JR, Stout JR, Thiery J, Ceglarek U, Stumvoll M, Blüher M, Stampfer MJ, Shai I. Intramyocellular triacylglycerol accumulation across weight loss strategies; Sub-study of the CENTRAL trial. PLoS One. 2017;12:e0188431.


Gepner Y, Shelef I, Schwarzfuchs D, Zelicha H, Tene L, Yaskolka Meir A, Tsaban G, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Komy O, Wolak A, Chassidim Y, Golan R, Avni-Hassid H, Bilitzky A, Sarusi B, Goshen E, Shemesh E, Henkin Y, Stumvoll MBlüher M, Thiery J, Ceglarek URudich A, Stampfer MJ, Shai I. Effect of distinct lifestyle interventions on mobilization of fast storage pools: the CENTRAL MRI randomized control trial. Circulation. 2017; Epub ahead of print.


Gepner Y, Shelef I, Schwarzfuchs D, Cohen N, Bril N, Rein M, Tsaban G, Zelicha H, Yaskolka Meir A, Tene L, Sarusy B, Rosen P, Hoffman JR, Stout JR, Thiery J, Ceglarek U, Stumvoll M, Blüher M, Stampfer MJ, Shai I. Intramyocellular triacylglycerol accumulation across weight loss strategies; Sub-study of the CENTRAL trial. PLoS One. 2017;12(11):e0188431


Gesing J, Scheuermann K, Wagner IV, Löffler D, Friebe D, Kiess W, Schuster V, Körner A. NAMPT serum levels are selectively elevated in acute infectious disease and in acute relapse of chronic inflammatory diseases in children. PLoS One. 2017;12:e0183027.


Gross A, Tönjes A, Scholz M. On the impact of relatedness on SNP association analysis. BMC Genet. 2017;18:104.


Haim Y, Blüher M, Konrad D, Goldstein N, Klöting N, Harman-Boehm I, Kirshtein B, Ginsberg D, Tarnovscki T, Gepner Y, Shai I, Rudich A. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tisue in obesity, molecularly defining a human dys-metabolic obese phenotype. Mol Metab. 2017;6:725-36.


Hankir MK, Kranz M, Keipert S, Weiner J, Andreasen SG, Kern M, Patt M, Klöting NHeiker JT, Hesse S, Brust P, Jastroch M, Fenske W. Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein 1 deficient mice. J Nucl Med. 2017;58:1100-3.


Hankir M. Loading and firing the brown adipocyte. Adipocyte. 2017; Epub ahead of print.


Hardikar S, Höchenberger R, Villringer A, Ohla K. Higher sensitivity to sweet and salty taste in obese compared to lean individuals. Appetite. 2017;111:158-65.


Hellrung L, Dietrich A, Hollmann M, Pleger B, Kalberlah C, Roggenhofer E, Villringer AHorstmann A. Intermittent compared to continuous real-time fMRI neurofeedback boosts control over amygdala activation. NeuroImage. 2017;166:198-208.


Hesselbarth N, Kunath A, Kern M, Gericke M, Mejhert N, Ryden M, Stumvoll MBlüher MKlöting N. Repin1 deficiency in adipose tissue improves whole-body insulin sensitivity, and lipid metabolism. Int J Obes (Lond). 2017; Epub ahead of print.


Kalenda A, Landgraf K, Löffler D, Kovacs PKiess WKörner A. The BDNF Val66Met polymorphism is associated with lower BMI, lower postprandial glucose levels and elevated carbohydrate intake in children and adolescents. Pediatr Obes. 2017; Epub ahead of print.


Kastner L, Kube J, Villringer ANeumann J. Cardiac concomitants of feedback and prediction error processing in reinforcement learning. Front Neurosci. 2017;11:598.


Kharabian Masouleh S, Beyer F, Lampe L, Loeffler M, Luck T, Riedel-Heller SG, Schroeter ML, Stumvoll MVillringer A, Witte AV. Gray matter structural networks are associated with cardiovascular risk factors in healthy older adults. J Cereb Blood Flow Metab. 2017; Epub ahead of print.


Koch M. Cannabinoid receptor signaling in central regulation of feeding behavior: a mini-review. Front Neurosci. 2017;11:293.


Kralisch S, Hoffmann A, Kratzsch J, Blüher MStumvoll MFasshauer M, Ebert T. The brown-fat-secreted adipokine neuregulin 4 is decreased in gestational diabetes mellitus. Diabetes Metab. 2017; Epub ahead of print.


Kralisch S, Hoffmann A, Klöting N, Bachmann A, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher M, Zhang MZ, Harris RC, Stumvoll MFasshauer M, Ebert T. FSTL3 is increased in renal dysfunction. Nephrol Dial Transplant. 2017;32:1637-44.


Kube J, Mathar D, Horstmann A, Villringer A, Neumann J. Altered monetary loss processing and reinforcement-based learning in individuals with obesity. Brain Imaging Behav. 2017; in press.


Landgraf K, Schuster S, Meusel A, Garten A, Riemer T, Schleinitz D, Kiess WKörner A. Short-term overfeeding of zebrafish with normal or high-fat diet as a model for the development of metabolically healthy versus unhealthy obesity. BMC Physiol. 2017;17:4.


Lede V, Meusel A, Garten A, Popkova Y, Penke M, Franke C, Ricken A, Schulz AKiess WHuster DSchöneberg TSchiller J. Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor. PLoS One. 2017;12:e0172000.


Löffler A, Luck T, Then FS, Luck-Sikorski C, Pabst A, Kovacs P, Böttcher Y, Breitfeld J, Tönjes AHorstmann A, Löffler M, Engel C, Thiery J, Villringer AStumvoll M, Riedel-Heller SG. Effects of psychological eating behaviour domains on the association between socio-economic status and BMI. Public Health Nutr. 2017;20:2706-12.


Mathar D, Neumann J, Villringer AHorstmann A. Failing to learn from negative prediction errors: Obesity is associated with alterations in a fundamental neural learning mechanism. Cortex. 2017;95:222-37.


Mehl N, Bergmann S, Klein AM, Daum M, von Klitzing K, Horstmann A. Cause or consequence? Investigating attention bias and self-regulation skills in children at risk for obesity. J Exp Child Psychol. 2017;155:113-27.


Meir AY, Tene L, Cohen N, Shelef I, Schwarzfuchs D, Gepner Y, Zelicha H, Rein M, Bril N, Serfaty D, Kenigsbuch S, Chassidim Y, Sarusy B, Dicker D, Thiery JCeglarek UStumvoll MBlüher M, Stampfer MJ, Rudich AShai I. Intrahepatic fat, abdominal adipose tissues, and metabolic state; magnetic resonance imaging study. Diabetes Metab Res Rev. 2017;32.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Adipocyte and epidermal fatty acid-binding protein serum concentrations in patients with lipodystrophy. Cytokine. 2017;92:20-3.


Oertwig K, Ulbricht D, Hanke S, Pippel J, Bellmann-Sickert K, Sträter NHeiker JT. Glycosylation of human vaspin (SERPINA12) and its impact on serpin activity, heparin binding and thermal stability. Biochim Biophys Acta. 2017;1865:1100-3.


Penke M, Schuster S, Gorski T, Gebhardt R, Kiess WGarten A. Oleate ameliorates palmite-induced reduction of NAMPT activity and NAD levels in primary human hepatocytes and hepatocarcinoma cells. Lipids Health Dis. 2017;16:191.


Polyakova M, Schlögl H, Sacher J, Schmidt-Kassow M, Kaiser J, Stumvoll M, Kratzsch J, Schroeter ML. Stability of BDNF in human samples stored up to 6 months and correlations of serum and EDTA-plasma concentrations. Int J Mol Sci. 2017;18:1189.


Popkova Y, Schiller J. TAG suppression by CsCl addition. Rapid Commun Mass Spetrom. 2017;31:411-8.


Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph SS, Lutter D, Yi CX, Graf E, García-Cáceres C, Legutko B, Fischer K, Brommage R, Zizzari P, Franklin BS, Krueger M, Koch M, Vettorazzi S, Li P, Hofmann SM, Bakhti M, Bastidas-Ponce A, Lickert H, Strom TM, Gailus-Durner V, Bechmann I, Perez-Tilve D, Tuckermann J, Hrabě de Angelis M, Sandoval D, Cota D, Latz E, Seeley RJ, Müller TD, DiMarchi RD, Finan B, Tschöp MH. Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. Cell Metab. 2017;26:620-32.


Raulien N, Friedrich K, Strobel S, Rubner S, Baumann S, von Bergen MKörner A, Krueger M, Rossol M, Wagner U. Fatty acid oxidation compensates for lipopolysaccharide-induced Warburg effect in glucose-deprived monocytes. Front Immunol. 2017;8:609.


Rodriguez FS, Schroeter ML, Witte AV, Engel C, Löffler M, Thiery J, Villringer A, Luck T, Riedel-Heller SG. Could high mental demands at work offset the adverse association between social isolation and cognitive functioning? Results of population-based LIFE-adult-study. Am J Geriatr Psychiatry. 2017;25:1258-69.


Rohde K, Klös M, Hopp L, Liu X, Keller M, Stumvoll M, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Kovacs P, Binder H, Blüher M, Böttcher Y. IRS1 DNA promoter methylation and expression in human adipose tissue are related to fat distribution and metabolic traits. Sci Rep. 2017;7:12369.


Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, Lichtner P, Ruffert C, Chen JM, Masson E, Beer S, Zimmer C, Seltsam K, Algül H, Bühler F, Bruno MJ, Bugert P, Burkhardt R, Cavestro GM, Cichoz-Lach H, Farré A, Frank J, Gambaro G, Gimpfl S, Grallert H, Griesmann H, Grützmann R, Hellerbrand C, Hegyi P, Hollenbach M, Iordache S, Jurkowska G, Keim V, Kiefer F, Krug S, Landt O, Leo MD, Lerch MM, Lévy P, Löffler M, Löhr M, Ludwig M, Macek M, Malats N, Malecka-Panas E, Malerba G, Mann K, Mayerle J, Mohr S, Te Morsche RHM, Motyka M, Mueller S, Müller T, Nöthen MM, Pedrazzoli S, Pereira SP, Peters A, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rösmann E, Saftoiu A, Schneider A, Schulz HU, Soranzo N, Soyka M, Simon P, Skipworth J, Stickel F, Strauch K, Stumvoll M, Testoni PA, Tönjes A, Werner L, Werner J, Wodarz N, Ziegler M, Masamune A, Mössner J, Férec C, Michl P, P H Drenth J, Witt H, Scholz M, Sahin-Tóth M; all members of the PanEuropean Working group on ACP. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. 2017; Epub ahead of print.


Schrimpf A, Kube J, Neumann J, Horstmann AVillringer A, Gaebler M. Parasympathetic cardio-regulation during social interactions in individuals with obesity - The influence of negative body image. Cogn Affect Behav Neurosci. 2017;17:330-47.


Schröter J, Schiller J. Chlorinated phospholipids and fatty acids: (Patho)Physiological relevance, potential toxicity, and analysis of lipid chlorohydrins. Oxid Med Cell Longev. 2016;2016:8386362.


Tönjes A, Scholz M, Krüger J, Krause K, Schleinitz D, Kirsten H, Gebhardt C, Marzi C, Grallert H, Ladenvall C, Heyne H, Laurila E, Kriebel J, Meisinger C, Rathmann W, Gieger C, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Fischer-Rosinsky A, Pfeiffer A, Krohn K, Spranger J, Thiery J, Blüher M, Stumvoll M, Kovacs P. Genome wide meta-analysis identifies novel determinants of circulating serum progranulin. Hum Mol Genet. 2017; Epub ahead of print.


Tsaban G, Wolak A, Avni-Hassid H, Gepner Y, Shelef I, Henkin Y, Schwarzfuchs D, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Tene L, Zelicha H, Yaskolka-Meir A, Komy O, Bilitzky A, Chassidim Y, Ceglarek UStumvoll MBlüher MThiery J, Dicker D, Rudich A, Stamper MJ, Shai I. Dynamics of intrapericardial and extrapericardial fat tissues during long-term, dietary-induced, moderate weight loss. Am J Clin Nutr. 2017;106:984-95.


Ulbricht D, Oertwig K, Arnsburg K, Saalbach A, Pippel J, Sträter NHeiker JT. Basic residues of ß-sheet a contribute to heparin binding and activation of vaspin (serpin A12). J Biol Chem. 2017;292:994-1004.


Wanka L, Babilon S, Burkert K, Mörl K, Gurevich VV, Beck-Sickinger AG. C-terminal motif of human neuropeptide Y4 receptor determines internalization and arrestin recruitment. Cell Signal. 2017;29:233-9.


Weiner J, Rohde K, Krause K, Zieger K, Klöting N, Kralisch S, Kovacs PStumvoll MBlüher M, Böttcher Y, Heiker JT. Brown adipose tissue (BAT) specific vaspin expression is increased after obesogenic diets and cold exposure and linked to acute changes in DNA-methylation. Mol Met. 2017;6:482-93.


Weise CM, Piaggi P, Reinhardt M, Chen K, Savage CR, Krakoff J, Pleger B. The obese brain as a heritable phenotype - A combined morphometry and twin study. Int J Obes (Lond). 2017;41:458-66.


Windholz J, Kovacs P, Schlicke M, Franke C, Mahajan A, Morris AP, Lemke JR, Klammt J, Kiess WSchöneberg T, Pfäffle R, Körner A. Copy number variations in "classical" obesity candidate genes are not frequently associated with severe early-onset obesity in children. J Pediatr Endocrinol Metab. 2017;30:507-15.


Zelicha H, Schwarzfuchs D, Shelef I, Gepner Y, Tsaban G, Tene L, Yaskolka Meir A, Bilitzky A, Komy O, Cohen N, Bril N, Rein M,Serfaty D, Kenigsbuch S, Chassidim Y, Sarusi B, Thiery J, Ceglarek U, Stumvoll M, Blüher M, Haviv YS, Stampfer MJ, Rudich A, Shai I.Changes of renal sinus fat and renal parenchymal fat during an 18-month randomized weight loss trial. Clin Nutr. 2017: S0261-5614(17)30146-2


Zieger K, Weiner J, Krause K, Schwarz M, Kohn M, Stumvoll MBlüher MHeiker JT. Vaspin suppresses cytokine-induced inflammation in 3T3-L1 adipocytes via inhibition of NFkB pathway. Mol Cell Endocrinol. 2017; Epub ahead of print.


Zieger K, Weiner J, Kunath A, Gericke M, Krause K, Kern M, Stumvoll MKlöting NBlüher MHeiker JT. Ablation of kallikrein 7 (KLK7) in adipose tissue ameliorates metabolic consequences of high-fat diet induced obesity by counteracting adipose tissue inflammation in vivo. Cell Mol Life Sci. 2017; Epub ahead of print.

2016

Barban N, Jansen R, de Vlaming R, Vaez A, Mandemakers JJ, Tropf FC, Shen X, Wilson JF, Chasman DI, Nolte IM, Tragante V, van der Laan SW, Perry JR, Kong A; BIOS Consortium, Ahluwalia TS, Albrecht E, Yerges-Armstrong L, Atzmon G, Auro K, Ayers K, Bakshi A, Ben-Avraham D, Berger K, Bergman A, Bertram L, Bielak LF, Bjornsdottir G, Bonder MJ, Broer L, Bui M, Barbieri C, Cavadino A, Chavarro JE, Turman C, Concas MP, Cordell HJ, Davies G, Eibich P, Eriksson N, Esko T, Eriksson J, Falahi F, Felix JF, Fontana MA, Franke L, Gandin I, Gaskins AJ, Gieger C, Gunderson EP, Guo X, Hayward C, He C, Hofer E, Huang H, Joshi PK, Kanoni S, Karlsson R, Kiechl S, Kifley A, Kluttig A, Kraft P, Lagou V, Lecoeur C, Lahti J, Li-Gao R, Lind PA, Liu T, Makalic E, Mamasoula C, Matteson L, Mbarek H, McArdle PF, McMahon G, Meddens SF, Mihailov E, Miller M, Missmer SA, Monnereau C, van der Most PJ, Myhre R, Nalls MA, Nutile T, Kalafati IP, Porcu E, Prokopenko I, Rajan KB, Rich-Edwards J, Rietveld CA, Robino A, Rose LM, Rueedi R, Ryan KA, Saba Y, Schmidt D, Smith JA, Stolk L, Streeten E, Tönjes A, Thorleifsson G, Ulivi S, Wedenoja J, Wellmann J, Willeit P, Yao J, Yengo L, Zhao JH, Zhao W, Zhernakova DV, Amin N, Andrews H, Balkau B, Barzilai N, Bergmann S, Biino G, Bisgaard H, Bønnelykke K, Boomsma DI, Buring JE, Campbell H, Cappellani S, Ciullo M, Cox SR, Cucca F, Toniolo D, Davey-Smith G, Deary IJ, Dedoussis G, Deloukas P, van Duijn CM, de Geus EJ, Eriksson JG, Evans DA, Faul JD, Sala CF, Froguel P, Gasparini P, Girotto G, Grabe HJ, Greiser KH, Groenen PJ, de Haan HG, Haerting J, Harris TB, Heath AC, Heikkilä K, Hofman A, Homuth G, Holliday EG, Hopper J, Hyppönen E, Jacobsson B, Jaddoe VW, Johannesson M, Jugessur A, Kähönen M, Kajantie E, Kardia SL, Keavney B, Kolcic I, Koponen P, Kovacs P, Kronenberg F, Kutalik Z, La Bianca M, Lachance G, Iacono WG, Lai S, Lehtimäki T, Liewald DC; LifeLines Cohort Study, Lindgren CM, Liu Y, Luben R, Lucht M, Luoto R, Magnus P, Magnusson PK, Martin NG, McGue M, McQuillan R, Medland SE, Meisinger C, Mellström D, Metspalu A, Traglia M, Milani L, Mitchell P, Montgomery GW, Mook-Kanamori D, de Mutsert R, Nohr EA, Ohlsson C, Olsen J, Ong KK, Paternoster L, Pattie A, Penninx BW, Perola M, Peyser PA, Pirastu M, Polasek O, Power C, Kaprio J, Raffel LJ, Räikkönen K, Raitakari O, Ridker PM, Ring SM, Roll K, Rudan I, Ruggiero D, Rujescu D, Salomaa V, Schlessinger D, Schmidt H, Schmidt R, Schupf N, Smit J, Sorice R, Spector TD, Starr JM, Stöckl D, Strauch K, Stumvoll M, Swertz MA, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tung JY, Uitterlinden AG, Vaccargiu S, Viikari J, Vitart V, Völzke H, Vollenweider P, Vuckovic D, Waage J, Wagner GG, Wang JJ, Wareham NJ, Weir DR, Willemsen G, Willeit J, Wright AF, Zondervan KT, Stefansson K, Krueger RF, Lee JJ, Benjamin DJ, Cesarini D, Koellinger PD, den Hoed M, Snieder H, Mills MC. Genome-wide analysis identifies 12 loci influencing human reproductive behavior. Nat Genet. 2016;48:1462-72.


Baum P, Kosacka J, Estrela-Lopis I, Woidt K, Serke H, Paeschke S, Stockinger M, Klöting NBlüher M, Dorn M, Classen J, Thiery JBechmann I, Toyka KV, Nowicki M. The role of nerve inflammation and exogenous iron load in experimental peripheral diabetic neuropathy (PDN). Metabolism. 2016;65:391-405.


Brune JE, Kern M, Kunath A, Flehmig G, Schön MR, Lohmann T, Dressler M, Dietrich A, Fasshauer MKovacs PStumvoll MBlüher MKlöting N. Fat depot-specific expression of HOXC9 and HOXC10 may contribute to adverse fat distribution and related metabolic traits. Obesity (Silver Spring). 2016;24:51-9.


Carmody RN, Dannemann M, Briggs AW, Nickel B, Groopmann EE, Wrangham RW, Kelso J. Genetic evidence of human adaption to a cooked diet. Genome Biol Evol. 2016;8:1091-103.


Dalgaard K, Landgraf K, Heyne S, Lempradi A, Longinotto J, Gossens K, Ruf M, Orthofer M, Strogantsev R, Selvaraj M, Tsai-Hsiu Lu T, Casas E, Teperino R, Surani MA, Zvetkova I, Rimmington D, Loraine Tung YCL, Lam B, Larder R, Yeo GSH, O'Rahilly S, Vavouri T, Whitelaw E, Penninger JM, Jenuwein T, Cheung CL, Ferguson-Smith AC, Coll AP, Körner A, Pospisilik JA. Trim28 haploinsufficiency triggers bi-stable epigenetic obesity. Cell. 2016;164:1-12.


Dannemann M, Andres AM, Kelso J. Introgression of Neandertal- and Denisovan-like haplotypes contributesto adaptive variation in human toll-like receptors. Am J Hum Genet. 2016;98:22-33.


Dietrich A, De Wit S, Horstmann A. General habit propensity relates to the sensation seeking subdomain of impulsivity but not obesity. Front Behav Neurosci. 2016;10:213.


Ebert T, Platz M, Kralisch S, Lossner U, Jessnitzer B, Richter J, Blüher MStumvoll MFasshauer M. Serum levels of copeptin are decreased in gestational diabetes mellitus. Exp Clin Endocrinol Diabetes. 2016;124:257-60.


Ehehalt S, Wiegand S, Körner A, Schweizer R, Liesenkötter KP, Partsch CJ, Blumenstock G, Spielau U, Denzer C, Ranke MB, Neu A, Binder G, Wabitsch M, Kiess W, Reinehr T. Low association between fasting and OGTT stimulated glucose levels with HbA1c in overweight children and adolescents. Pediatr Diabetes. 2016; Epub ahead of print.


Ehehalt S, Wiegand S, Körner A, Schweizer R, Liesenkötter KP, Partsch CJ, Blumenstock G, Spielau U, Denzer C, Ranke MB, Neu A, Binder G, Wabitsch M, Kiess W, Reinehr T. Low association between fasting and OGTT stimulated glucose levels with HbA1c in overweight children and adolescents. Pediatr Diabetes. 2016; Epub ahead of print.


Felix JF, Bradfield JP, Monnereau C, van der Valk RJ, [47 authors], Kiess W, [14 authors], Pfäffle R, [33 authors], Körner A, [9 authors], Grant SF, Jaddoe VW, Early Growth Genetics C, Bone Mineral Density in Childhood Study BC. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet. 2016;25:389-403.


Fu Q, Posth C, Hajdinjak M, Petr M, Mallick S, Fernandes D, Furtwängler A, Haak W, Meyer M, Mittnik A, Nickel B, Peltzer A, Rohland N, Slon V, Talamo S, Lazaridis I, Lipson M, Mathieson I, Schiffels S, Skoglund P, Derevianko AP, Drozdov N, Slavinsky V, Tsybankov A, Cremonesi RG, Mallegni F, Gely B, Vacca E, Morales MR, Straus LG, Neugebauer-Maresch C, Teschler-Nicola M, Constantin S, Moldovan OT, Benazzi S, Peresani M, Coppola D, Lari M, Ricci S, Ronchitelli A, Valentin F, Thevenet C, Wehrberger K, Grigorescu D, Rougier H, Crevecoeur I, Flas D, Semal P, Mannino MA, Cupillard C, Bocherens H, Conard NJ, Harvati K, Moiseyev V, Drucker DG, Svoboda J, Richards MP, Caramelli D, Pinhasi R, Kelso J, Patterson N, Krause J, Pääbo S, Reich D. The genetic history of Ice Age Europe. Nature. 2016;534:200-5.


Garcia-Garcia I, Kube J, Gaebler M, Horstmann AVillringer ANeumann J. Neural processing of negative emotional stimuli and the influence of age, sex and task-related characteristics. Neurosci Biobehav Rev. 2016;68:773-93.


Gepner Y, Bril N, Shelef I, Schwarzfuchs D, Serfaty D, Rein M, Cohen N, Shemesh E, Tangi-Rosental O, Sarusi B, Goshen E, Kenigsbuch S1, Chassidim Y, Golan R, Witkow S, Henkin Y, Stampfer MJ, Rudich A, Shai I.Higher visceral adiposity is associated with an enhanced early thermogenic response to carbohydrate-rich food.Clin Nutr. 2016 Apr;35(2):422-427


Grellmann C, Neumann J, Bitzer S, Kovacs PTönjes A, Westlye LT, Anreassen OA, Stumvoll MVillringer AHorstmann A. Random projection for fast and efficient multivariate correlation analysis of high-dimensional data: A new approach. Front Genet. 2016;7:102.


Guiu-Jurado E, Unthan M, Böhler N, Kern M, Landgraf K, Dietrich A, Schleinitz D, Ruschke K, Klöting NFaßhauer MTönjes AStumvoll MKörner AKovacs PBlüher M. Bone morphogenetic protein 2 (BMP2) may contribute to partition of energy storage into visceral and subcutaneous fat depots. Obesity (Silver Spring). 2016;24:2092-100.


Hankir MK, Kranz M, Gnad T, Weiner J, Wagner S, Deuther-Conrad W, Bronisch F, Steinhoff K, Luthardt J, Klöting N, Hesse S, Seibyl JP, Sabri O, Heiker JTBlüher M, Pfeifer A, Brust P, Fenske WK. A novel thermoregulatory role for PDE10A in mouse and human adipocytes. EMBO Mol Med. 2016;8:796-812.


Hoffmann A, Manjowk GM, Wagner V, Klöting N, Ebert T, Jessnitzer B, Lössner U, Stukenborg JB, Blüher MStumvoll M, Söder O, Svechnikov K, Fasshauer M, Kralisch S. Leptin within the subphysiological to physiological range dose-dependently improves male reproductive function in an obesity mouse model. Endocrinology. 2016;157:2641-8.


Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR, Gaulton KJ, Grarup N, Bradfield JP, Strachan DP, Li-Gao R, Ahluwalia TS, Kreiner E, Rueedi R, Lyytikäinen LP, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Hottenga JJ, Vilor-Tejedor N, Joshi PK, Boh ET, Ntalla I, Pitkänen N, Mahajan A, van Leeuwen EM, Joro R, Lagou V, Nodzenski M, Diver LA, Zondervan KT, Bustamante M, Marques-Vidal P, Mercader JM, Bennett AJ, Rahmioglu N, Nyholt DR, Ma RC, Tam CH, Tam WH; CHARGE Consortium Hematology Working Group, Ganesh SK, van Rooij FJ, Jones SE, Loh PR, Ruth KS, Tuke MA, Tyrrell J, Wood AR, Yaghootkar H, Scholtens DM, Paternoster L, Prokopenko I, Kovacs P, Atalay M, Willems SM, Panoutsopoulou K, Wang X, Carstensen L, Geller F, Schraut KE, Murcia M, van Beijsterveldt CE, Willemsen G, Appel EV, Fonvig CE, Trier C, Tiesler CM, Standl M, Kutalik Z, Bonàs-Guarch S, Hougaard DM, Sánchez F, Torrents D, Waage J, Hollegaard MV, de Haan HG, Rosendaal FR, Medina-Gomez C, Ring SM, Hemani G, McMahon G, Robertson NR, Groves CJ, Langenberg C, Luan J, Scott RA, Zhao JH, Mentch FD, MacKenzie SM, Reynolds RM; Early Growth Genetics (EGG) Consortium, Lowe WL, Tönjes AStumvoll M, Lindi V, Lakka TA, van Duijn CM, Kiess W, Körner A, Sørensen TI, Niinikoski H, Pahkala K, Raitakari OT, Zeggini E, Dedoussis GV, Teo YY, Saw SM, Melbye M, Campbell H, Wilson JF, Vrijheid M, de Geus EJ, Boomsma DI, Kadarmideen HN, Holm JC, Hansen T, Sebert S, Hattersley AT, Beilin LJ, Newnham JP, Pennell CE, Heinrich J, Adair LS, Borja JB, Mohlke KL, Eriksson JG, Widén E, Kähönen M, Viikari JS, Lehtimäki T, Vollenweider P, Bønnelykke K, Bisgaard H, Mook-Kanamori DO, Hofman A, Rivadeneira F, Uitterlinden AG, Pisinger C, Pedersen O, Power C, Hyppönen E, Wareham NJ, Hakonarson H, Davies E, Walker BR, Jaddoe VW, Järvelin MR, Grant SF, Vaag AA, Lawlor DA, Frayling TM, Smith GD, Morris AP, Ong KK, Felix JF, Timpson NJ, Perry JR, Evans DM, McCarthy MI, Freathy RM. Genome-wide associations for birth weight and correlations with adult disease. Nature. 2016;538:248-52.


Jendrny C, Beck-Sickinger AG. Inhibition of kallikrein-related peptidases 7 and 5 by grafting serpin reactive-center loop sequences onto sunflower trypsin inhibitor-1 (SFTI-1). Chembiochem. 2016;17:719-26.


Keller M, Hopp L, Liu X, Wohland T, Rohde K, Cancello R, Klös M, Bacos K, Kern M, Eichelmann F, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll MKovacs P, DiBlasio AM, Ling C, Binder H, Blüher M, Böttcher Y. Genome-wide DNA promoter methylation and transcriptome analysis in human adipose tissue unravels novel candidate genes for obesity. Mol Metab. 2016;6:86-100.


Kharabian Masouleh S, Arelin K, Horstmann A, Lample L, Kipping JA, Luck T, Riedel-Heller SG, Schroeter ML, Stumvoll MVillringer A, Witte AV. Higher body mass index in older adults is associated with lower gray matter volume: implications for memory performance. Neurobiol Aging. 2016;40:1-10.


Köbe T, Witte AV, Schnelle A, Grittner U, Tesky VA, Pantel J, Schuchardt JP, Hahn A, Bohlken J, Rujescu D, Flöel A. Vitamin B-12 concentration, memory performance, and hippocampal structure in patients with mild cognitive impairment. Am J Clin Nutr. 2016;103:1045-54.


Köbe T, Witte AV, Schnelle A, Lesemann A, Fabian S, Tesky VA, Pantel J, Flöel A. Combined omega-3 fatty acids, aerobic exercise and cognitive stimulation prevents decline in gray matter volume of the frontal, parietal and cingulate cortex in patients with mild cognitive impairment. Neuroimage. 2016;131:226-38.


Kube J, Schrimpf A, Garcia-Garcia I, Villringer ANeumann JHorstmann A. Differential heart rate responses to social and monetary reinforcement in women with obesity. Psychophysiology. 2016;53:868-79.


Kumar S, Grundeis F, Brand C, Hwang HJ, Mehnert J, Pleger B. Differences in insula and pre-/frontal responses during reappraisal of food in lean and obese humans. Front Hum Neurosci. 2016;10:233.


Kunath A, Hesselbarth N, Gericke M, Kern M, Dommel S, Kovacs PStumvoll MBlüher MKlöting N. Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation. Biochem Biophys Res Commun. 2016;478:398-402.


Kunath A, Klöting N. Adipocyte biology and obesity-mediated adipose tissue remodeling. Obesity Medicine. 2016;4:15-20.

Landgraf K, Scholz M, Kovacs P, Kiess W, Körner A. FTO obesity risk variants are linked to adipocyte IRX3 expression and BMI of children - relevance of FTO variants to defend body weight in lean children? PLoS One. 2016;11:e0161739.


Lazaridis I, Nadel D, Rollefson G, Merrett DC, Rohland N, Mallick S, Fernandes D, Novac M, Gamarra B, Sirak K, Connell S, Stewardson K, Harney E, Fu Q, Gonzales-Fortes G, Jones ER, Roodenberg SA, Lengyel G, Bocquentin F, Gasparian B, Monge JM, Gregg M, Eshed V, Mizrahi AS, Meiklejohn C, Gerritsen F, Bejenaru L, Blüher M, Campbell A, Cavalleri G, Comas D, Froguel P, Gilbert E, Kerr SM, Kovacs P, Krause J, McGettigan D, Merrigan M, Merriwether DA, O'Reilly S, Richards MB, Semino O, Shamoon-Pour M, Stefanescu G, Stumvoll MTönjes A, Torroni A, Wilson JF, Yengo L, Hovhannisyan NA, Patterson N, Pinhasi R, Reich D. Genomic insights into the origin of farming in the ancient Near East. Nature. 2016;536:419-24.


Lede V, Franke C, Meusel A, Teupser D, Ricken A, Thiery JSchiller JHuster DSchöneberg TSchulz A. Severe atherosclerosis and hypercholesterolemia in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptor. PLoS One. 2016;11:e0167888.


Löffler D, Behrendt S, Creemers JW, Klammt J, Aust G, Stanik J, Kiess W, Kovacs PKörner A. Functional and clinical relevance of novel and known PCSK1 variants for childhood obesity and glucose metabolism. Mol Metab. 2016;6:295-305.


Mathar D, Horstmann APleger BVillringer ANeumann J. Is it worth the effort? Novel insights into obesity-associated alterations ins cost-benefit decision-making. Front Behav Neurosci. 2016;9:360.


Mathar D, Wilkinson L, Holl A, Neumann J, Deserno L, Villringer A, Jahanshahi M, Horstmann A. The role of dopamine in positive and negative prediction error utilization during incidental learning–insights from Positron Emission Tomography, Parkinson’s disease and Huntington’s disease. Cortex. 2016; Epub ahead of print.


Melasch J, Rullmann M, Hilbert A, Luthardt J, Becker GA, Patt M, Stumvoll MBlüher MVillringer A, Arelin K, Meyer PM, Bresch A, Sabri O, Hesse S, Pleger B. Sex differences in serotonin-hypothalamic connections underpin a diminished sense of emotional well-being with increasing body weight. Int J Obes (Lond). 2016;40:1268-77.


Melasch J, Rullmann M, Hilbert A, Luthardt J, Becker GA, Patt M, Villringer A, Arelin K, Meyer PM, Lobsien D, Ding Y-S, Müller K, Sabri O, Hesse S, Pleger B. The central nervours norepinephrine network links a diminished sense of emotional well-being to an increased body weight. Int J Obes. 2016;40:779-87.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Progranulin is increased in human and murine lipodystrophy. Diabetes Res Clin Pract. 2016;120:1-7.


Miehle K, Ebert T, Kralisch S, Hoffmann A, Kratzsch J, Schlögl H, Stumvoll MFasshauer M. Serum concentrations of fibroblast growth factor 21 are elevated in patients with congenital or acquired lipodystrophy. Cytokine. 2016;83:239-44.


Mühlberg C, Mathar D, Villringer AHorstmann ANeumann J. Stopping at the sight of food - How gender and obesity impact on response inhibition. Appetite. 2016;107:663-76.


Orthgiess J, Gericke M, Immig K, Schulz A, Hirrlinger J, Bechmann IEilers J. Neurons exhibit Lyz2 promotor activity in vivo: Implications for using LysM-Cre mice in myeloid cell research. Eur J Immunol. 2016;46:1529-32.


Pecht T, Haim Y, Bashan N, Shapiro H, Harman-Boehm I, Kirshtein B, Clement K, Shai I, Rudich A. Circulating blood monocyte subclasses and lipid-laden adipose tissue macrophages in human obesity. PLoS One. 2016;11:e0159350.


Pfeiffer S, Krüger J, Maierhofer A, Böttcher Y, Klöting N, El Hajj N, Schleinitz D, Schön MR, Dietrich A, Fasshauer M, Lohmann T, Dreßler M, Stumvoll M, Haaf T, Blüher MKovacs P. Hypoxia-inducible factor 3A gene expression and methylation in adipose tissue is related to adipose tissue dysfunction. Sci Rep. 2016;6:27969.


Prasad RB, Lessmark A, Almgren P, Kovacs G, Hansson O, Oskolkov N, Vitai M, Ladenvall C, Kovacs P, Fadista J, Lachmann M, Zhou Y, Sonestedt E, Poon W, Wollheim CB, Orho-Melander M, Stumvoll M, Tuomi T, Pääbo S, Koranyi L, Groop L. Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes. Diabetologia. 2016;59:1702-13.


Ried JS, Jeff M J, Chu AY, Bragg-Gresham JL, van Dongen J, Huffman JE, Ahluwalia TS, Cadby G, Eklund N, Eriksson J, Esko T, Feitosa MF, Goel A, Gorski M, Hayward C, Heard-Costa NL, Jackson AU, Jokinen E, Kanoni S, Kristiansson K, Kutalik Z, Lahti J, Luan J, Mägi R, Mahajan A, Mangino M, Medina-Gomez C, Monda KL, Nolte IM, Pérusse L, Prokopenko I, Qi L, Rose LM, Salvi E, Smith MT, Snieder H, Stančáková A, Ju Sung Y, Tachmazidou I, Teumer A, Thorleifsson G, van der Harst P, Walker RW, Wang SR, Wild SH, Willems SM, Wong A, Zhang W, Albrecht E, Couto Alves A, Bakker SJ, Barlassina C, Bartz TM, Beilby J, Bellis C, Bergman RN, Bergmann S, Blangero J, Blüher M, Boerwinkle E, Bonnycastle LL, Bornstein SR, Bruinenberg M, Campbell H, Chen YI, Chiang CW, Chines PS, Collins FS, Cucca F, Cupples LA, D'Avila F, de Geus EJ, Dedoussis G, Dimitriou M, Döring A, Eriksson JG, Farmaki AE, Farrall M, Ferreira T, Fischer K, Forouhi NG, Friedrich N, Gjesing AP, Glorioso N, Graff M, Grallert H, Grarup N, Gräßler J, Grewal J, Hamsten A, Harder MN, Hartman CA, Hassinen M, Hastie N, Hattersley AT, Havulinna AS, Heliövaara M, Hillege H, Hofman A, Holmen O, Homuth G, Hottenga JJ, Hui J, Husemoen LL, Hysi PG, Isaacs A, Ittermann T, Jalilzadeh S, James AL, Jørgensen T, Jousilahti P, Jula A, Marie Justesen J, Justice AE, Kähönen M, Karaleftheri M, Tee Khaw K, Keinanen-Kiukaanniemi SM, Kinnunen L, Knekt PB, Koistinen HA, Kolcic I, Kooner IK, Koskinen S, Kovacs P, Kyriakou T, Laitinen T, Langenberg C, Lewin AM, Lichtner P, Lindgren CM, Lindström J, Linneberg A, Lorbeer R, Lorentzon M, Luben R, Lyssenko V, Männistö S, Manunta P, Leach IM, McArdle WL, Mcknight B, Mohlke KL, Mihailov E, Milani L, Mills R, Montasser ME, Morris AP, Müller G, Musk AW, Narisu N, Ong KK, Oostra BA, Osmond C, Palotie A, Pankow JS, Paternoster L, Penninx BW, Pichler I, Pilia MG, Polašek O, Pramstaller PP, Raitakari OT, Rankinen T, Rao DC, Rayner NW, Ribel-Madsen R, Rice TK, Richards M, Ridker PM, Rivadeneira F, Ryan KA, Sanna S, Sarzynski MA, Scholtens S, Scott RA, Sebert S, Southam L, Sparsø TH, Steinthorsdottir V, Stirrups K, Stolk RP, Strauch K, Stringham HM, Swertz MA, Swift AJ, Tönjes A, Tsafantakis E, van der Most PJ, Van Vliet-Ostaptchouk JV, Vandenput L, Vartiainen E, Venturini C, Verweij N, Viikari JS, Vitart V, Vohl MC, Vonk JM, Waeber G, Widén E, Willemsen G, Wilsgaard T, Winkler TW, Wright AF, Yerges-Armstrong LM, Hua Zhao J, Carola Zillikens M, Boomsma DI, Bouchard C, Chambers JC, Chasman DI, Cusi D, Gansevoort RT, Gieger C, Hansen T, Hicks AA, Hu F, Hveem K, Jarvelin MR, Kajantie E, Kooner JS, Kuh D, Kuusisto J, Laakso M, Lakka TA, Lehtimäki T, Metspalu A, Njølstad I, Ohlsson C, Oldehinkel AJ, Palmer LJ, Pedersen O, Perola M, Peters A, Psaty BM, Puolijoki H, Rauramaa R, Rudan I, Salomaa V, Schwarz PE, Shudiner AR, Smit JH, Sørensen TI, Spector TD, Stefansson K, Stumvoll M, Tremblay A, Tuomilehto J, Uitterlinden AG, Uusitupa M, Völker U, Vollenweider P, Wareham NJ, Watkins H, Wilson JF, Zeggini E, Abecasis GR, Boehnke M, Borecki IB, Deloukas P, van Duijn CM, Fox C, Groop LC, Heid IM, Hunter DJ, Kaplan RC, McCarthy MI, North KE, O'Connell JR, Schlessinger D, Thorsteinsdottir U, Strachan DP, Frayling T, Hirschhorn JN, Müller-Nurasyid M, Loos RJ. A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape. Nat Commun. 2016;;7:13357.


Quach H, Rotival M, Pothlichet J, Loh YE, Dannemann M, Zidane N, Laval G, Patin E, Harmant C, Lopez M, Deschamps M, Naffakh N, Duffy D, Coen A, Leroux-Roels G, Clément F, Boland A, Deleuze JF, Kelso J, Albert ML, Quintana-Murci L. Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations. Cell. 2016;167:643-656.


Rockstroh D, Löffler D, Kiess W, Landgraf K, Körner A. Regulation of human adipogenesis by miR125b-5p. Adipocyte. 2016;5:283-97.


Saalbach A, Tremel J, Herbert D, Schwede K, Wandel E, Schirmer C, Anderegg U, Beck-Sickinger AGHeiker JT, Schultz S, Magin T, Simon JC. Anti-inflammatory action of keratinocyte-derived vaspin: relevance for the pathogenesis of psoriasis. Am J Pathol. 2016;186:639-51.


Schlögl H, Müller K, Horstmann A, Miehle K, Püschel J, Villringer APleger BStumvoll MFasshauer M. Leptin substitution in patients with lipodystrophy: Neural correlates for long-term success in the normalization of eating behavior. Diabetes. 2016;65:2179-86.


Schlögl H, Horstmann AVillringer AStumvoll M. Functional neuroimaging in obesity and the potential for development of novel treatments. Lancet Diabetes Endocrinol. 2016;4:695-705.


Schreier M, Schwartze JT, Landgraf K, Scheuermann K, Erbs S, Herberth G, Pospisilik JA, Kratzsch J, Kiess W, Körner A. Osteopontin is BMI-independently related to early endothelial dysfunction in children. J Clin Endocrinol Metab. 2016;101:4161-9.


Schröter J, Griesinger H, Reuß E, Schulz M, Riemer T, Süß R, Schiller J, Fuchs B. Unexpected products of the hypochlorous acid-induced oxidation of oleic acid: A study using high performance thin-layer chromatography-electrospray ionization mass spectrometry. J Chromatogr A. 2016;1439:89-96.


Schröter J, Schiller J. Chlorinated phospholipids and fatty acids: (patho)physiological relevance, potential toxicity, and analysis of lipid chlorohydrins. Oxid Med Cell Longev. 2016;2016:8386362.


Sjoerds Z, Dietrich A, Deserno L, de Wit S, Villringer A, Heinze HJ, Schlagenhauf F, Horstmann A. Slips of action and sequential decisions: A cross-validation study of tasks assessing habitual and goal-directed action control. Front Behav Neurosci. 2016;10:234.


Slutsky N, Vatarescu M, Haim Y, Goldstein N, Kirshtein B, Harman-Boehm I, Gepner Y, Shai I, Bashan N, Blüher MRudich A. Decreased adiponectin links elevated adipose tissue autophagy with adipocyte endocrine dysfunction in obesity. Int J Obes (Lond). 2016;40:912-20.


Stelzner K, Herbert D, Popkova Y, Lorz A, Schiller JGericke MKlöting NBlüher M, Franz S, Simon JCSaalbach A. Free fatty acids sensitize dendritic cells to amplify TH1/TH17-immune responses. Eur J Immunol. 2016;46:2043-53.


Thieme V, Jolly N, Madsen AN, Bellmann-Sickert K, Schwartz TW, Holst B, Cox HM, Beck-Sickinger AG. High molecular weight PEGylation of human pancreatic polypeptide at position 22 improves stability and reduces food intake in mice. Br J Pharmacol. 2016;173:3208-21.


Vausort M, Salgado-Somoza A, Zhang L, Leszek P, Scholz M, Teren A, Burkhardt RThiery J, Wagner DR, Devaux Y. Myocardial infarction-associated circular RNA predicting left ventricular dysfunction. J Am Coll Cardiol. 2016;68:1247-8.


Vernot B, Tucci S, Kelso J, Schraiber JG, Wolf AB, Gittelman RM, Dannemann M, Grote S, McCoy RC, Norton H, Scheinfeldt LB, Merriwether DA, Koki G, Friedlaender JS, Wakefield J, Pääbo S, Akey JM. Excavating Neandertal and Denisovan DNA from the genomes of Melanesian individuals. Science. 2016;352:235-9.


Wagner IV, Klöting N, Atanassova N, Savchuk I, Spröte C, Kiess W, Söder O, Svechnikov K. Prepubertal onset of obesity negatively impacts on testicular steroidogenesis in rats. Mol Cell Endocrinol. 2016;437:154-62.

Weiner J, Kranz M, Klöting N, Kunath A, Steinhoff K, Rijntjes E, Köhrle J, Zeisig V, Hankir M, Gebhardt C, Deuther-Conrad W, Heiker JTFasshauer MStumvoll MBlüher M, Sabri O, Hesse S, Brust P, Tönjes A, Krause K. Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissue in mice. Sci Rep. 2016;6:38124.


Weingarten A, Turchetti L, Krohn K, Klöting I, Kern M, Kovacs PStumvoll MBlüher MKlöting N. Novel genes on rat chromosome 10 are linked to body fat mass, preadipocyte number and adipocyte size. Int J Obes (Lond). 2016;40:1832-40.


Welker F, Hajdinjak M, Talamo S, Jaouen K, Dannemann M, David F, Julien M, Meyer M, Kelso J, Barnes I, Brace S, Kamminga P, Fischer R, Kessler BM, Stewart JR, Pääbo S, Collins MJ, Hublin JJ. Palaeoproteomic evidence identifies archaic hominins associated with the Chatelperronian at the Grotte du Renne. Proc Natl Acad Sci U S A. 2016;113:11162-7.


Winkler TW, Justice AE, Graff M, [...], Blüher M, [...], Kovacs P, [...], Tönjes A, [...], Stumvoll M, [...], Loos RJ. Correction: The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study. PLoS Genet. 2016;12:e1006166.


Yaskolka Meir A, Shelef I, Schwarzfuchs D, Gepner Y, Tene L, Zelicha H, Tsaban G, Bilitzky A, Komy O, Cohen N, Bril N, Rein M, Serfaty D, Kenigsbuch S, Chassidim Y, Zeller L, Ceglarek U, Stumvoll M, Blüher M, Thiery J, Stampfer MJ, Rudich A, Shai I. Intermuscular adipose tissue and thigh muscle area dynamics during an 18-month randomized weight loss trial. J Appl Physiol (1985);121(2):518-27.

2015

Breitling C, Gross A, Büttner P, Weise S, Schleinitz D, Kiess W, Scholz M, Kovacs PKörner A. Genetic contribution of variants near SORT1 and APOE on LDL cholesterol independent of obesity in children. PLoS One. 2015;10:e0138064.


Burkhardt R, Kirsten H, Beutner F, Holdt LM, Gross A, Teren A, Tönjes A, Becker S, Krohn K, Kovacs PStumvoll M, Teupser D, Thiery J, Ceglarek U, Scholz M. Integration of genome-wide SNP data and gene-expression profiles reveals six novel loci and regulatory mechanisms for amino acids and acylcarnitines in whole blood. PLoS Genet. 2015;11:e1005510.


Deserno L, Wilbertz T, Reiter A, Horstmann ANeumann JVillringer A, Heinze HJ, Schlagenhauf F. Lateral prefrontal model-based signatures are reduced in individuals with high trait impulsivity. Transl Psychiatry. 2015;5:e659.


du Plessis J, van Pelt J, Korf H, Mathieu C, van der Schueren B, Lannoo M, Oyen T, Topal B, Fetter G, Nayler S, van der Merwe T, Windmolders P, van Gaal L, Verrijken A, Hubens G, Gericke M, Cassiman D, Francque S, Nevens F, van der Merwe S. Association of adipose tissue inflammation with histological severity of non-alcoholic fatty liver disease. Gastroenterology. 2015;149:635-48.


Garcia-Garcia I, Jurado MA, Garolera M, Marques-Iturria I, Horstmann A, Segura B, Pueyo R, Sender-Palacios MJ, Vernet-Vernet M, Villringer A, Junque C, Margulies DS, Neumann J. Functional network centrality in obesity: A resting-state and task fMRI study. Psychiatry Res. 2015;233:331-8.


Gericke M, Weyer U, Braune J, Bechmann IEilers J. A method for long-term live-imaging of tissue macrophages in adipose tissue explants. Am J Physiol Endocrinol Metab. 2015;308:E1023-33.


Grellmann C, Bitzer S, Neumann J, Westlye LT, Andreasseen OA, Villringer AHorstmann A. Comparison of variants of canonical correlation analysis and partial least squares for combined analysis of MRI and genetic data. Neuroimage. 2015;107C:289-310.


Garcia-Garcia I, , Jurado MA, Garolera M, Marques-Iturria I, Horstmann A, Segura B, Pueyo R, Sender-Palacios MJ, Vernet-Vernet M, Villringer A, Junque C, Margulies DS, Neumann J. Functional network centrality in obesity: A resting-state and task fMRI study. Psychiatry Res. 2015;233:3331-8.


Haim Y, Blüher M, Slutsky N, Goldstein N, Klöting N, Harman-Boehm I, Kirshstein B, Ginsberg D, Gericke M, Guiu Jurado E, Kovsan J, Tarnovscki T, Kachko L, Bashan N, Gepner Y, Shai I, Rudich A. Elevated autophagy gene expression in adipose tissue of humans: A potential non-cell-cycle-dependent function of E2F1. Autophagy. 2015;11:2074-88.


Hankir MK, Ashrafian H, Hesse S, Horstmann A, Fenske WK. Distinctive striatal dopamine signaling after dieting and gastric bypass. Trends Endocrinol Metab. 2015;26:223-30.

Hellrung L, Hollmann M, Zscheyge O, Schlumm T, Kalberlah C, Roggenhofer E, Okon-Singer H, Villringer AHorstmann A. Flexible adaptive paradigms for fMRI using a novel software package 'Brain Analysis in Real-Time' (BART). PLoS One. 2015;10:e0118890.


Hesselbarth N, Petinelli C, Gericke M, Berger C, Kunath A, Stumvoll MBlüher MKlöting N. Tamoxifen affects glucose and lipid metabolism parameters, causes browning of subcutaneous adipose tissue and transient body composition changes in C57BL/6NTac mice. Biochem Biophys Res Commun. 2015;464:724-9.


Horstmann A, Dietrich A, Mathar D, Pössel M, Villringer ANeumann J. Slave to habit? Obesity is associated with decreased behavioural sensitivity to reward devaluation. Appetite. 2015;87:175-83.


Horstmann A, Fenske WK, Hankir MK. Argument for a non-linear relationship between severity of human obesity and dopaminergic tone. Obes Rev. 2015;16:821-30.


Huhn S, Kharabian Masouleh S, Stumvoll MVillringer A, Witte V. Components of a Mediterranean diet and their impact on cognitive functions in aging. Front Aging Neurosci. 2015;7:132.


Kaiser A, Müller P, Zellmann T, Scheidt HA, Thomas L, Bosse M, Meier R, Meiler J, Huster DBeck-Sickinger AG, Schmidt P. Unwinding of the C-terminal residues of neuropeptide Y is critical for Y2 receptor binding and activation. Angew Chem Int Ed Engl. 2015;54:7446-9.


Kälin S, Heppner FL, Bechmann I, Prinz M, Tschöp MH, Yi CX. Hypothalamic innate immune reaction in obesity. Nat Rev Endocrinol. 2015;11:339-51.


Kannt A, Pfenniger A, Teichert L, Tönjes A, Dietrich A, Schön MR, Klöting NBlüher M. Association of nicotinamide-N-methyltransferase mRNA expression in human aidpose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance. Diabetologia. 2015;58:799-808.


Kilian TM, Klöting N, Bergmann R, Els-Heindl S, Babilon S, Clement-Ziza M, Zhang Y, Beck-Sickinger AG, Chollet C. Rational design of dual peptides targeting ghrelin and Y2 receptors to regulate food intake and body weight. J Med Chem. 2015;58:4180-93.


Klöting N, Hesselbarth N, Gericke M, Kunath A, Biemann R, Chakaroun R, Kosacka J, Kovacs P, Kern M, Stumvoll M, Fischer B, Rolle-Kampczyk U, Feltens R, Otto W, Wissenbach DK, von Bergen M, BlüherM. Di-(2 Ehtylhexyl)-Phtalate (DEHP) causes impaired adipocyte function and alters serum metabolites. PLoS One. 2015;10:e0143190.


Knigge A, Klöting N, Schön MR, Dietrich A, Fasshauer M, Gärtner D, Lohmann T, Dreßler M, Stumvoll MKovacs PBlüher M. ADCY5 gene expression in adipose tissue is related to obesity in men and mice. PLoS One. 2015;10:e0120742.


Koch M, Varela L, Kim JG, Kim JD, Hernández-Nuño F, Simonds SE, Castorena CM, Vianna CR, Elmquist JK, Morozov YM, Rakic P, Bechmann I, Cowley MA, Szigeti-Buck K, Dietrich MO, Gao XB, Diano S, Horvath TL. Hypothalamic POMC neurons promote cannabinoid-induced feeding. Nature. 2015;519:45-50.


Kosacka J, Kern M, Klöting N, Paeschke S, Rudich A, Haim Y, Gericke M, Serke H, Stumvoll MBechmann I, Nowicki M, Blüher M. Autophagy in adipose tissue of patients with obesity and type 2 diabetes. Mol Cell Endocrinol. 2015;409:21-31.


Kralisch S, Klöting N, Ebert T, Kern M, Hoffmann A, Krause K, Jessnitzer B, Lossner U, Sommerer I, Stumvoll MFasshauer M. Circulating adipocyte fatty acid-binding protein induces insulin resistance in mice in vivo. Obesity (Silver Spring). 2015;23:1007-13.


Krause K, Weiner J, Hönes S, Klöting N, Rijntjes E, Heiker JT, Gebhardt C, Köhrle J, Führer D, Steinhoff K, Hesse S, Moeller LC, Tönjes A. The effects of thyroid hormones on gene expression of acyl-coenzyme A thioesterases in adipose tissue and liver of mice. Eur Thyroid J. 2015;4 (suppl 1):59-66.


Lakowa N, Trieu N, Flehmig G, Lohmann T, Schön MR, Dietrich A, Zeplin PH, Langer S, Stumvoll MBlüher MKlöting N. Telomere length differences between subcutaneous and visceral adipose tissue in humans. Biochem Biophys Res Commun. 2015;457:426-32.


Landgraf K, Rockstroh D, Wagner IV, Weise S, Tauscher R, Schwarze JT, Löffler D, Bühligen U, Wojan M, Till H, Kratzsch J, Kiess W, Blüher MKörner A. Evidence of early alterations in adipose tissue biology and function and its association with obesity-related inflammation and insulin resistance in children. Diabetes. 2015;64:1249-61.


Löffler A, Luck T, Then FS, Luppa M, Sikorski C, Kovacs PTönjes A, Böttcher Y, Breitfeld J, Horstmann A, Löffler M, Engel C, Thiery JStumvoll M, Riedel-Heller SG. Age- and gender-specific norms for the German version of the Three-Factor Eating-Questionnaire (TFEQ). Appetite. 2015;91:241-7.


Löffler A, Luck T, Then FS, Sikorski C, Kovacs P, Böttcher Y, Breitfeld J, Tönjes AHorstmann A, Löffler M, Engel C, Thiery JVillringer AStumvoll M, Riedel-Heller SG. Eating behaviour in the general population: An analysis of the factor structure of the German version of the Three-Factor-Eating-Questionnaire (TFEQ) and its association with the body mass index. PLoS One. 2015;10:e0133977.


Löffler D, Müller U, Scheuermann K, Friebe D, Gesing J, Bielitz J, Erbs S, Landgraf K, Wagner IV, Kiess W, Körner A. Serum irisin levels are regulated by acute strenous exercise. J Clin Endocrinol Metab. 2015;100:1289-99.


Löffler D, Landgraf K, Körner A, Kratzsch J, Kirkby KC, Himmerich H. Modulation of triglyceride accumulation in adipocytes by psychopharmacological agents in vitro. J Psychiatr Res. 2015;72:37-42.


Mardinoglu A, Heiker JT, Gärtner D, Björnson E, Schön MR, Flehmig G, Klöting N, Krohn K, Fasshauer MStumvoll M, Nielsen J, Blüher M. Extensive weight loss reveals distinct gene expression changes in human subcutaneous and visceral adipose tissue. Sci Rep. 2015;5:14841.


Mueller K, Möller HE, Horstmann A, Busse-Voigt FP, Lepsien J, Blüher MStumvoll MVillringer APleger B. Physical exercise in overweight to obese individuals induces metabolic- and neurotrophic-related structural brain plasticity. Front Hum Neurosci. 2015;9:372.


Park M, Sivertsen BB, Els-Heindl S, Huber T, Holst B, Beck-Sickinger AG, Schwartz TW, Sakmar TP. Bioorthogonal labeling of ghrelin receptor to facilitate studies of ligand-dependent conformational dynamics. Chem Biol. 2015;22:1431-6.


Pippel J, Küttner EB, Ulricht D, Daberger J, Schultz S, Heiker JTSträter N. Crystal structure of cleaved vaspin (serpinA12). Biol Chem. 2016;397:111-23.


Popkova Y, Meusel A, Breitfeld J, Schleinitz D, Hirrlinger J, Dannenberger D, Kovacs PSchiller J. Nutrition-dependent changes of mouse adipose tissue compositions monitored by NMR, MS, and chromatographic methods. Anal Bioanal Chem. 2015;407:5113-23.


Qi Q, Downer MK, Kilpelainen TO, Taal HR, Barton SJ, Ntalla I, Standl M, Boraska V, Huikari V, Kiefte-de Jong JC, Körner A, Lakka TA, Liu G, Magnusson J, Okuda M, Raitakari O, Richmond R, Scott RA, Bailey ME, Scheuermann K, Holloway JW, Inskip H, Isasi CR, Mossaar-Rahmani Y, Jaddoe VW, Laitinen J, Lindi V, Melen E, Pitsiladis Y, Pitkanen N, Snieder H, Heinrich J, Timpson NJ, Wang T, Yuji H, Zeggini E, Dedoussis GV, Kaplan RC, Wylie-Rosett J, Loos RJ, Hu FB, Qi L. Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents. Diabetes. 2015;64:2467-76

Rockstroh D, Landgraf K, Wagner IV, Gesing J, Tauscher R, Lakowa N, Kiess W, Bühligen U, Wojan M, Till H, Blüher MKörner A. Direct evidence of brown adipocytes in different fat depots in children. PLoS One. 2015;10:e0117841.


Rohde K, Keller M, Horstmann A, Liu X, Eichelmann F, Stumvoll MVillringer AKovacs PTönjes A, Böttcher Y. Role of genetic variants in ADIPOQ in human eating behavior. Genes Nutr. 2015;10:449.


Rohde K, Federbusch M, Horstmann A, Keller M, Villringer AStumvoll MTönjes AKovacs P, Böttcher Y. Genetic variants in AKR1B10 associate with human eating behavior. BMC Genet. 2015;16:31.


Ronke C, Dannemann M, Halbwax M, Fischer A, Helmschrodt C, Brügel M, André C, Atencia R, Mugisha L, Scholz M, Ceglarek U, Thiery J, Pääbo S, Prüfer K, Kelso J. Lineage-specific changes in biomarkers in great apes and humans. PLoS One. 2015;10:e0134548.


Schrey S, Wurst U, Ebert T, Kralisch S, Drewlo S, Stepan H, Lössner U, Platz M, Kratzsch J, Stumvoll MFasshauer M. The adipokine preadipocyte factor-1 is downregulated in preeclampsia and expressed in placenta. Cytokine. 2015;75:338-43.


Schunter JA, Löffler D, Wiesner T, Kovacs P, Badenhoop K, Aust G, Tönjes A, Müller P, Baber R, Simon JC, Führer D, Pfäffle RW, Thiery JStumvoll M, Kiess W, Kratzsch J, Körner A. A novel FoxD3 variant is associated with vitiligo and elevated thyroid auto-antibodies. J Clin Endocrinol Metab. 2015;100:E1335-42.


Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, [ ….],Kovacs P, [….], Zillikens MC, McCarthy MI, Speliotes EK, North KE, Fox CS, Barroso I, Franks PW, Ingelsson E, Heid IM, Loos RJ, Cupples LA, Morris AP, Lindgren CM, Mohlke KL. New genetic loci link adipose and insulin biology to body fat di stribution. Nature. 2015;518:187-96.


Simmank J, Murawski C, Bode S, Horstmann A. Incidental rewarding cues influence economic decisions in people with obesity. Front Behav Neurosci. 2015;9:278.


Stenkamp-Strahm CM, Nyavor YE, Kappmeyer AJ, Horton S, Gericke M, Balemba OB. Prolonged high fat diet ingestion, obesity, and type 2 diabetes symptoms correlate with phenotypic plasticity in myenteric neurons and nerve damage in the mouse duodenum. Cell Tissue Res. 2015;361:411-26.


Ulbricht D, Pippel J, Schultz S, Meier R, Sträter NHeiker JT. A unique serpin P1' glutamate and a conserved beta-sheet C arginine are key residues for activity, protease recognition and stability of serpinA12 (vaspin). Biochem J. 2015;470:357-67.


van der Valk RJ, Kreiner-Moller E, Kooijman MN, Guxens M, Stergiakouli E, Saaf A, Bradfield JP, Geller F, Hayes MG, Cousminer DL, Körner A, Thiering E, Curtin JA, [42 authors], Kiess W, Mahajan A, [45 authors], Sergeyev E, [14 authors], Bonnelykke K, Jaddoe VW. A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet. 2015;24:1155-68.


Voisin S, Almen MS, Zheleznyakova GY, Lundberg L, Zarei S, Castillo S, Eriksson FE, Nilsson EK, Blüher M, Böttcher Y, Kovacs P, Klovins J, Rask-Andersen M, Schiöth HB. Many obesity-associated SNPs strongly associate with DNA methylation changes at proximal promoters and enhancers. Genome Med. 2015;7:103.


Weiß CL, Dannemann M, Prüfer K, Burbano HA. Contesting the presence of wheat in the British Isles 8,000 years ago by assessing ancient DNA authenticity from low-coverage data. Elife. 2015;4.


Winkler TW, Justice AE, Graff M, [...], Blüher M, [...], Kovacs P, [...], Stumvoll M, [...], Loos RJ. The influence of age and sex on genetic associations with adult body size and shape: A large-scale genome-wide interaction study. PLoS One. 2015;11:e1005378.

2014

Benyamin B, Esko T, Ried JS, Radhakrishnan A, Vermeulen SH, Traglia M, Gögele M, Anderson D, Broer L, Podmore C, Luan J, Kutalik Z, Sanna S, van der meer P, Tanaka T, Wang F, Westra HJ, Franke L, Mihailov E, Milani L, Häldin J, Winkelmann J, Meitinger T, Thiery J, Peters A, Waldenberger M, Rendon A, Jolley J, Sambrook J, Kiemeney LA, Sweep FC, Sala CF, Schwienbacher C, Pichler I, Hui J, Demirkan A, Isaacs A, Amin N, Steri M, Waeber G, Verweij N, Powell JE, Nyholt DR, Heath AC, Madden PA, Visscher Uda M, Vollenweider P, Scott RA, Langenberg C, Wareham N; InterAct Consortium, van Dujin C, Beilgy J, Pramstaller PP, Hicks AA, Ouwehand WH, Oexle K, Gieger C, Metspalu A, Camaschella C, Toniolo D, Swinkels DW, Whitfield JB. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nat Commun. 2014;5:4926.


Berry R, Church CD, Gericke MT, Jeffery E, Colman L, Rodeheffer MS. Imaging of adipose tissue. Methods Enzymol. 2014;537:47-73


Blüher MKlöting N, Wueest S, Schoenle EJ, Schön MR, Dietrich A, Fasshauer MStumvoll M, Konrad D. Fas and FasL Expression in Human Adipose Tissue Is Related to Obesity, Insulin Resistance, and Type 2 Diabetes. J Clin Endocrinol Metab . 2014;99:E36-44.


Ceglarek U, Dittrich J, Helmschrodt C, Wagner K, Nofer JR, Thiery J, Becker S. Preanalytical standardization of sphingosine-1-phosphate, sphinganine-1-phosphate and sphingosine analysis in human plasma by liquid chromatography-tandem mass spectrometry. Clin Chim Acta. 2014;435:1-6.


Cousminer DL, Stergiakouli E, Berry DJ, Ang W, Groen-Blokhuis MM, Körner A, Siitonen N, Ntalla I, Marinelli M, Perry JR, Kettunen J, Jansen R, Surakka I, Timpson NJ, Ring S, Mcmahon G, Power C, Wang C, Kähönen M, Viikari J, Lehtimäki T, Middeldorp CM, Hulshoff Pol HE, Neef M, Weise S, Pahkala K, Niinikoski H, Zeggini E, Panoutsopoulou K, Bustamante M, Penninx BW; ReproGen Consortium, Murabito J, Torrent M, Dedoussis GV, Kiess W, Boomsma DI, Pennell CE, Raitakari OT, Hyppönen E, Davey Smith G, Ripatti S, McCarthy MI, Widén E; Early Growth Genetics Consortium. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum Mol Genet. 2014;23:4452-64.


Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, Lee H, Oskolkov N, Fadista J, Ehlers K, Wahl S, Hoffmann C, Qian K, Rönn T, Riess H, Müller-Nurasyid M, Bretschneider N, Schroeder T, Skurk T, Horsthemke B; DIAGRAM+Consortium, Spieler D, Klingenspor M, Seifert M, Kern MJ, Mejhert N, Dahlman I, Hansson O, Hauck SM, Blüher M, Arner P, Groop L, Illig T, Suhre K, Hsu YH, Mellgren G, Hauner H, Laumen H. Leveraging cross-species transcription factor binding site patterns: from diabetes risk Loci to disease mechanisms. Cell. 2014;156:343-58.


Cottilard A, Poitou C, Torcivia A, Bouillot JL, Dietrich A, Klöting N, Gregoire C, Lolmede K, Blüher M, Clement K. Adipocyte size treshold matters: link with risk of type 2 diabetes and improved insulin resistance after gastric bypass. J Clin Endocrinol Metab. 2014;99:E1466-70.


Cousminer DL, Stergiakouli E, Berry DJ, Ang W, Groen-Blokhuis MM, Körner A, Siitonen N, Ntalla I, Marinelli M, Perry JR, Kettunen J, Jansen R, Surakka I, Timpson NJ, Ring S, McMahon G, Power C, Wang C, Kahonen M, Viikari J, Lehtimaki T, Mitteldorp CM, Hulshoff Pol HE, Neef M, Weise S, Pahkala K, Niinikoski H, Zeggini E, Panoutsopoulou K, Bustamante M, Penninx BW, Murabito J, Torrent M, Dedoussis GV, Kiess W, Boomsma DI, Pennell CE, Raitakari OT, Hypponen E, Davey SG, Ripatti S, McCarthy MI, Widen E. Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum Mol Genet. 2014;23:4452-64.


Derikx MH, Kovacs P, Scholz M, Masson E, Chen JM, Ruffert C, Lichtner P, Te Morsche RH, Cavestro GM, Algül H, Berg T, Bödeker H, Blüher M, Bruno MJ, Buch S, Bugert P, Cichoz-Lach H, Dabrowski A, Farré A, Frank J, Gasiorowska A, Geisz A, Goni E, Grothaus J, Grützmann R, Haas S, Hampe J, Hellerbrand C, Hegyi P, Huster D, Ioana M, Iordache S, Jurkowska G, Keim V, Landt O, Di Leo M, Lerch MM, Lévy P, Löhr MJ, Macek M, Malats N, Malecka-Panas E, Mariani A, Martorana D, Mayerle J, Mora J, Mössner J, Müller S, Ockenga J, Paderova J, Pedrazzoli S, Pereira SP, Pfützer R, Real FX, Rebours V, Ridinger M, Rietschel M, Rohde K, Sack S, Saftoiu A, Schneider A, Schulz HU, Syoka M, Simon P, Skipworth J, Stickel F, Stumvoll M, Testoni PA, Tönjes A, Treiber M, Weiss FU, Werner J, Wodarz N, Férec C, Drenth JP, Witt H, Rosendahl J. Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut. 2014;64:1426-33.


Diaz Gimenez LE, Babilon S, Wanka L, Beck-Sickinger AG, Gurevich VV. Mutations in arrestin-3 differentially affect binding to neuropeptide Y receptor subtypes. Cell Signal. 2014;26:1523-31.


Dietrich A*, Federbusch MG*, Grellmann C, Villringer AHorstmann A. Body weight status, eating behavior, sensitivity to reward/punishment, and gender: relationships and interdependencies. Front Psychol. 2014;5:1073. *contributed equally.

Ebert T, Roth I, Richter J, Tönjes A, Kralisch S, Lossner U, Kratzsch J,Blüher MStumvoll MFasshauer M. Different associations of adipokines in lean and healthy adults.  Horm Metab Res. 2014;46:41-7


Ebert T, Stepan H, Schrey S, Kralisch S, Hindricks J, Hopf L, Platz M, Lossner U, Jessnitzer B, Drewlo S, Blüher MStumvoll M,Fasshauer M. Serum levels of irisin in gestational diabetes mellitus during pregnancy and after delivery. Cytokine. 2014;65:153-8.

Ebert T, Focke D, Petroff D, Wurst U, Richter J, Bachmann A, Lössner U, Kralisch S, Kratzsch J, Beige J, Bast I, Anders M, Blüher MStumvoll MFasshauer M. Serum levels of the myokine irisin in relation to metabolic and renal function. Eur J Endocrinol. 2014;170:501-6.


Ebert T, Hindricks J, Kralisch S, Lößner U, Jeßnitzer B, Richter J, Blüher MStumvoll MFasshauer M. Serum levels of fractalkine are associated with markers of insulin resistance in gestational diabetes mellitus. Diabetic Med. 2014;31:1014-7.


Ebert T, Kralisch S, Hoffmann A, Bachmann A, Lössner U, Kratzsch J, Blüher MStumvoll MTönjes AFaßhauer M. Circulation angiopoietin-like protein 8 is independently associated with fasting plasma glucose and type 2 diabetes mellitus. J Clin Endocrinol Metab. 2014;99:E2510-7.


Eibisch M, Popkova Y, Süß R, Schiller J, Dannenberger D. Evaluation of a commercial enzymatic test kit regarding the quantitative analysis of different free fatty acids. Anal Bioanal Chem. 2014;406:7410-5.


Fasshauer MBlüher MStumvoll M. Adipokines in gestational diabetes. Lancet Diabetes Endocrinol. 2014;2:488-99.


Flehmig G, Scholz M, Klöting NFasshauer MTönjes AStumvoll M, Youn BS, Blüher M. Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation. PLoS One. 2014;9:e99785.


Garcia-Garcia I, Horstmann A, Jurado MA, Garolea M, Chaudhry SJ, Margulies DS, Villringer ANeumann J. Reward processing in obesity, substance addiction and non-substance addiction. Obes Rev. 2014;11:853-69.


Garnov N, Linder N, Schaudinn A, Blüher M, Karlas T, Schütz T, Dietrich A, Kahn T, Busse H. Comparison of T1 relaxation times in adipose tissue of severely obese patients and healthy lean subjects measured by 1.5 T MRI. NMR Biomed. 2014;27:1123-8.


Griesinger H, Fuchs B, Süß R, Matheis K, Schulz M, Schiller J. Stationary phase thickness determines the quality of thin-layer chromatography/matrix-assisted laser desorption and ionization mass spectra of lipids. Anal Biochem Chem. 2014;406:1291-306.


Haase J, Weyer U, Immig K, Klöting NBlüher MEilers JBechmann I, Gericke M. Local proliferation of macrophages in adipose tissue during obesity-induced inflammation.  Diabetologia. 2014;57:562-71.


Heiker JT*, Kunath A*, Kosacka J, Flehmig G, Knigge A, Kern M, Stumvoll MKovacs PBlüher MKlöting N. Identification of genetic loci associated with different responses to high fat died induced obesity (DIO) in C57BL/6N and C57BL/6J substrains. Physiol Genomics. 2014;46:377-84. (*contributed equally)

Heiker JT. Vaspin (serpinA12) in obesity, insulin resistance, and inflammation. J Pept Sci. 2014;20:299-306.


Helmschrodt C, Becker S, Thiery J, Ceglarek U. Preanalytical standardization for reactive oxygen species derived oxysterol analysis in human plasma by liquid chromatography-tandem mass spectrometry. Biochem Biophys Res Commun. 2014;446:726-30.


Hindricks J, Ebert T, Bachmann A, Kralisch S, Lössner U, Kratzsch J, Stolzenburg JU, Dietel A, Beige J, Anders M, Bast I, Blüher MStumvoll MFasshauer M. Serum levels of fibroblast growth factor-21 are increased in chronic and acute renal dysfunction. Clin Endocrinol. 2014;80:918-24.


Jaskolla TW, Onischke K, Schiller J. 2,5-Dihydroxybenzoic acid salts for matrix-assisted laser desorption/ionization time-of-flight mass spectrometric lipid analysis: Simplified spectra interpretation and insights into gasphase fragmentation. Rapid Commun Mass Spectrom. 2014;28:1353-63.


Keller M, Kralisch S, Rohde K, Schleinitz D, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Tönjes A, Stumvoll M, Kovacs P, Faßhauer M, Blüher M, Böttcher Y. Global DNA methylation levels in human adipose tissue are related to fat distribution and glucose homeostasis. Diabetologia. 2014;57:2374-83.


Kelso J, Prüfer K. Ancient humans and the origin of modern humans.Curr Opin Gen Dev. 2014;29:133-8.


Kern M, Kosacka J, Hesselbarth N, Brückner J, Heiker JT, Flehmig G, Klöting I, Kovacs P, Matz-Soja M, Gebhardt R, Krohn K, Sales S, Abshagen K, Shevchenko A, Stumvoll MBlüher MKlöting N. Liver-restricted Repin1 deficiency improves whole body insulin sensitivity, alters lipid metabolism and causes secondary changes in adipose tissue in mice. Diabetes. 2014;63:3295-309.


Khrameeva EE, Bozek K, He L, Yan Z, Jiang X, Wei Y, Tang K, Gelfand MS, Prufer K, Kelso J, Paabo S, Giavalisco P, Lachmann M, Khaitovich P. Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans. Nat Commun. 2014;5:3584.


Kralisch S, Ebert T, Lossner U, Jesnitzer B, Stumvoll MFasshauer M. Adipocyte fatty acid binding protein is released from adipocytes by a non-conventional mechanism. Int J Obes (Lond). 2014;38:1251-4.


Lo JC, Ljubicic S, Leibiger B, Kern M, Leibiger IB, Moede T, Kelly ME, Chatterjee Bhowmick D, Murano I, Cohen P, Banks AS, Khandekar MJ, Dietrich A, Flier JS, Cinti S, Blüher M, Danial NN, Berggren PO, Spiegelman BM. Adipsin is an adipokine that improves β cell function in diabetes. Cell. 2014;158:41-53.


Mäde V, Babilon S, Jolly N, Wanka L, Bellmann-Sickert K, Diaz Gimenez LE, Mörl K, Cox HM, Gurevich VV, Beck-Sickinger AG. Peptide modifications differentialy alter G protein-coupled receptor internalization and signaling bias. Angew Chem Int Ed. 2014;53:10067-71.


Mäde V, Els-Heindl S, Beck-Sickinger AG. Automated solid-phase peptide synthesis to obtain therapeutic peptides. Beilstein J Org Chem. 2014;10:1197-212.


Mangner N, Scheuermann K, Winzer E, Wagner I, Hoellriegel R, Sandri M, Zimmer M, Mende M, Linke A, Kiess W, Schuler G, Körner AErbs S. Childhood obesity: Impact on cardiac geometry and function. JACC Cardiovasc Imaging. 2014;7:1198-205.


Maric S, Skar-Gislinge N, Midtgaard S, Thygesen MB, Schiller J, Frielinghaus H, Moulin M, Haertlein M, Forsyth VT, Günther-Pomorski T, Arleth L. Stealtth carriers for low-resolution structure determination of membrance proteins in solution. Acta Cryst. 2014;70:317-28.


Mattern A, Zellmann T, Beck-Sickinger AG. Processing, signaling, and physiological function of chemerin. IUBMB Life. 2014;66:19-26.


Müller K*, Horstmann A*, Möller HE, Anwander A, Lepsien J, Schroeter ML, Villringer APleger B. Obesity associated cerebral gray and white matter alterations are interrelated in the female brain. PLoS One. 2014;9:e114206. (*contributed equally)

Nimptsch A, Pyttel S, Paasch U, Mohr C, Heinrich JM, Schiller J. A MALDI MS Investigation of the Lysophosphatidylcholine/Phosphatidylcholine Ratio in Human Spermatozoa and Erythrocytes as a Useful Fertility Marker. Lipids. 2014;49:287-93.


Pecht T, Gutman-Tirosh A, Bashan N, Rudich A. Peripheral blood leucocyte subclasses as potential biomarkers of adipose tissue inflammation and obesity subphenotypes in humans. Obes Rev. 2014;15:322-37.


Pedragosa-Badia X, Sliwoski GR, Dong Nguyen E, Lindner D, Stichel J, Kaufmann KW, Meiler J, Beck-Sickinger AG. Pancreatic polypeptide is recognized by two hydrophobic domains of the human Y4 receptor binding pocket. J Biol Chem. 2014;289:5846-59.


Pirkl A, Meier M, Popkova Y, Letzel MC, Schnapp A, Schiller J, Dreisewerd K. Analysis of free fatty acids by ultraviolet laser desorption ionization mass spectrometry using insect wings as hydrophobic sample substrates. Anal Chem. 2014;86:10763-71.


Rohde K, Keller M, Klös M, Schleinitz D, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll MKovacs PBlüher M, Böttcher Y. Adipose tissue depot specific promotor methylation of TMEM18. J Mol Med. 2014;92:881-8.


Schleinitz D, Klöting N, Lindgren CM, Breitfeld J, Dietrich A, Schön MR, Lohmann T, Dreßler M, Stumvoll M, McCarthy MI, Blüher MKovacs P. Fat depot-specific mRNA expression of novel loci associated with waist-hip ratio. Int J Obes (Lond). 2014;38:120-5.


Schleinitz D, Böttcher Y, Blüher MKovacs P. The genetics of fat distribution. Diabetologia. 2014;57:1276-86.


Stienstra R, Haim Y, Riahi Y, Netea M, Rudich A, Leibowitz G. Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes. Diabetologia. 2014;57:1505-16.


Stöckl D, Peters A, Thorand B, Heier M, Koenig W, Seissler J, Thiery J, Rathmann W, Meisinger C. Reproductive factors, intima media thickness and carotid plaques in a cross-sectional study of postmenopausal women enrolled in the population-based KORA F4 study. BMC Womens Health. 2014;14:17.


Tönjes A, Scholz M, Breitfeld J, Marzi C, Grallert H, Gross A, Ladenvall C, Schleinitz D, Krause K, Kirsten H, Laurila E, Kriebel J, Thorand B, Rathmann W, Groop L, Prokopenko I, Isomaa B, Beutner F, Kratzsch J, Thiery JFasshauer MKlöting N, Gieger C, Blüher MStumvoll MKovacs P. Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genet. 2014;10:e1004854.


Wilbertz T, Deserno L, Horstmann ANeumann JVillringer A, Heinze HJ, Boehler CN, Schlagenhauf F. Response inhibition and its relation to multidimensional impulsivity. Neuroimage. 2014;103:241-8.


Zschörnig K, Schiller J. A simple method to generate oxidized phosphotidylcholines in amounts close to one milligram. Chem Phys Lipids. 2014;184:30-7.

2013

Gast MT, Tönjes A, Keller M, Horstmann A, Steinle N, Scholz M, Müller I, Villringer AStumvoll MKovacs P, Böttcher Y. The role of rs2237781 within GRM8 in eating behavior. Brain Behav. 2013;3:495-502.


Haim Y, Tarnovscki T, Bashari D, Rudich A. A chromatin immunoprecipitation (ChIP) protocol for use in whole human adipose tissue. Am J Physiol Endocrinol Metab. 2013;305:E1172-7.


Horstmann AKovacs P, Kabisch S, Boettcher Y, Schlögl H, Tönjes AStumvoll MPleger BVillringer A. Common genetic variation near MC4R has a sex-specific impact on human brain structure and eating behavior. PLoS One. 2013;8:e74362.


Heiker JT, Kern M, Kosacka J, Flehmig G, Stumvoll M, Shang E, Lohmann T, Dreßler M, Kovacs PBlüher MKlöting N. Nicotinamide nucleotide transhydrogenase mRNA expression is related to human obesity.  Obesity (Silver Spring). 2013;21:529-34.


Hoffmeister A, Tuennemann J, Sommerer I, Mössner J, Rittger A, Schleinitz D, Kratzsch J, Rosendahl J, Klöting N, Stahl T, Rossner S, Paroni F, Maedler K, Kovacs PBlüher M. Genetic and biochemical evidence for a functional role of BACE1 in the regulation of insulin mRNA expression. Obesity (Silver Spring). 2013;21:E626-33.


Hollmann M, Pleger BVillringer AHorstmann A. Brain imaging in the context of food perception and eating. Curr Opin Lipidol. 2013;24:18-24. Review.


Keller M, Schleinitz D, Förster J, Tönjes A, Böttcher Y, Fischer-Rosinsky A, Breitfeld J, Weidle K, Rayner NW, Burkhardt R, Enigk B, Müller I, Halbritter J, Koriath M, Pfeiffer A, Krohn K, Groop L, Spranger J, Stumvoll MKovacs P. THOC5 : a novel gene involved in HDL-cholesterol metabolism. J Lipid Res. 2013;54:3170-6.


Keller M, Liu X, Wohland T, Rohde K, Gast MT, Stumvoll M, Kovacs PTönjes A, Böttcher Y. TAS2R38 and its influence on smoking behavior and glucose homeostasis in the German Sorbs. PLoS One. 2013;8:e80512.


Kosacka J, Koch K, Gericke M, Nowicki M, Heiker JT, Klöting I, Stumvoll MBlüher M, Klöting N. The polygenetically inherited metabolical syndrome of male WOKW rats is associated with enhanced autophagy in adipose tissue. Diabetol Metabol Syndr. 2013;5:23.


Kosacka J, Nowicki M, Blüher M, Baum P, Stockinger M, Toyka KV, Klöting I, Stumvoll M, Serke H, Bechmann IKlöting N. Increased autophagy in peripheral nerves may protect Wistar Ottawa Karlsburg W rats against neuropathy. Exp Neurol. 2013;250:125-35.


Kovacs P, Miehle K, Sandner B, Stumvoll MBlüher M. Insulin administration acutely decreases vaspin serum concentrations in humans. Obes Facts. 2013;6:86-8.


Krist J, Wieder K, Klöting N, Oberbach A, Kralisch S, Wiesner T, Schön MR, Gärtner D, Dietrich A, Shang E, Lohmann T, Dreßler M, Fasshauer MStumvoll MBlüher M. Effects of weight loss and exercise on apelin serum concentrations and adipose tissue expression in human obesity. Obes Facts. 2013;6:57-69.


Machann J, Horstmann A, Born M, Hesse S, Hirsch FW. Diagnostic imaging in obesity. Best Pract Res Clin Endocrinol Metab. 2013;27:261-77. Review.


Mai M, Tönjes AKovacs PStumvoll M, Fiedler GM, Leichtle AB. Serum levels of acylcarnitines are altered in prediabetic conditions. PLoS One. 2013;8:e82459.


Nimptsch A, Fuchs B, Süß R, Zschörnig K, Jakop U, Göritz F, Schiller J, Müller K. A simple method to identify ether lipids in spermatozoa samples by MALDI-TOF mass spectrometry. Anal Bioanal Chem. 2013;405:6675-82.


Scheidt HA, Meyer T, Nikolaus J, Baek DJ, Haralampiev I, Thomas L, Bittmann R, Müller P, Herrmann A, Huster D. Cholesterol's Aliphatic Side Chain Modulates Membrane Properties. Angew Chem Int Ed. 2013;52:12848–51.


Schlögl H*, Kabisch S*, Horstmann A, Lohmann G, Müller K, Lepsien J, Busse-Voigt F, Kratzsch J, Pleger BVillringer AStumvoll A. Exenatide-induced reduction in energy intake is associated with increase in hypothalamic connectivity. Diabetes Care. 2013;36:1933-40. (*contributed equally)

Blüher M, Klöting N, Schlich R, Willems M, Ruppe F, Knoefel WT, Dietrich A, Fielding BA, Arner P, Frayn KN, Eckel J. Adipose dipeptidyl peptidase-4 and obesity: correlation with insulin resistance and depot-specific release from adipose tissue in vivo and in vitro. Diabetes Care. 2013;36:4083-90.


Steingroever H, Wetzels R, Horstmann ANeumann J, Wagenmakers EJ. Performance of healthy participants on the Iowa Gambling Task. Psychol Assess. 2013;25:180-93. Review.


Wegener J, Zschörnig K, Onischke K, Fuchs B, Schiller J, Müller K. Conservation of honey bee (Apis mellifera) sperm phospholipids during storage in the bee queen — A TLC/MALDI–TOF MS study. Exp Gero. 2013;48:213-22 .