Curriculum 2016

23.2.–12.4. Workshop: Introduction to R
10.5.–21.6. Workshop: Introduction to R
23.–27.5. IRTG module: Principles of clinical studies
21.–24.6. IRTG module: Protein expression, purification and characterization
19.–21.10. Summer School at Burg Hohnstein
19.–21.10. IRTG module: Cloning Club
28.11.–2.12. IRTG module: Clinical basis of obesity


Principles of clinical studies

Principles of Clinical Studies

The seminar provides an introduction to design and conduct clinical Trials (including legal requirements). The module will take place in Leipzig from 23 to 27 May 2016.


Montag, 23. Mai

09:00–09:15 Begrüßung/Kurzvorstellung
Oana Brosteanu
09:15–10:00 Einführung Überblick Studiendesigns
Oana Brosteanu
10:00–11:00 Vorstellung der ADIPO_VENT-Studie
Philipp Simon
11:20–11:50 Allgemeine Hinweise zur Prüfplanerstellung
Oana Brosteanu
11:50–12:20 Übung zum Prüfplan
Oana Brosteanu

Dienstag, 24. Mai


Studiendesign und Fallzahlplanung
David Petroff


Diskussion zum Prüfplan der ADIPO_Vent-Studie
David Petroff


David Petroff


Mittwoch, 25. Mai

09:00–10:30 Rechtliche Grundlagen klinischer Studien
Peggy Houben
10:45–12:15 Aufgaben der Ethikkommission in klinischen Studien
Ortrun Riha


Donnerstag, 26. Mai

09:00–10:00 Patienteninformation und Datenschutz
Peggy Houben
 10:00–11:00 Dokumentation klinischer Studien
Bianca Scholze
11:15–12:15 Umgang mit unerwünschten Ereignissen
Madlen Dörschmann


Freitag, 27. Mai

09:00–10:00 Vorstellung Studie II: BARO DIET-Studie
Tatjana Schütz
10:00–11:00 Vorstellung Studie III: Exenatide: Plazebo-kontrollierte Crossover-Studie mit Neuroimaging
Haiko Schlögl
11:30–12:30 Das Projekt Klinische Studie
Oana Brosteanu
12:30–13:00 "Research: increasing value, reducing waste"
Oana Brosteanu
13:30–14:30 Abschlussklausur


Sprache: deutsch

Maximale Teilnehmerzahl: 20

Credit points: 1 (unbenotet)

Ort: Zentrum für Klinische Studien Leipzig, Härtelstraße 16 - 18

Protein expression, purification and characterization

Scientific module "Protein expression, purification and characterization"

This course introduces modern techniques of recombinant expression and purification of proteins, including expression in E.coli as well as eukaryotic expression systems. Special attention will be given to adipocytokines. Analysis will include spectroscopic methods (mass spectrometry, 3D structure analysis methods) and cell based signalling tools. The seminar will take place in Leipzig from 21 to 24 June 2016.


Tuesday, 21 June 2016


Lecture: Cloning, protein expression (E.coli, mammal cells, in vitro expression systems) and purification
Annette Beck-Sickinger
12:15–13:15 Guided lab tour an practical demonstration on protein expression
Kathrin Bellmann-Sickert


Wednesday, 22 June 2016


Lecture: Protein crystallization - not just trial and error
Norbert Sträter


Lecture: X-ray structure determination - walking around in electron density
Norbert Sträter
12:10–13:10 Practical course: Crystallography
Norbert Sträter


Thursday, 23 June 2016


Lecture: Introduction to NMR 1+2
Practical course: Recordning and assignment of an NMR spectrum
Anja Penk


Friday, 24 June 2016


Lecture: Protein analytics, Edman sequencing, MS/MS methods
Practical course: MALDI MS
John Heiker

Set up:
Maximum number of participants: 10
Credit points: 1 (ungraded)
Venues: Institute of Biochemistry (Brüderstraße 34), Institute of Biophysics and Medical Physics and BBZ.

Please register for the course by sending an e-mail to Anja Pohl until 31 May


Clinical Basis of Obesity

Scientific seminar "Clinical Basis of Obesity"

This seminar serves as an introduction to current problems and challenges of obesity management as seen in dermatology, endocrinology, pediatrics and cardiology.


Monday, 28 November 2016


From adipocytes to adiposity and its sequelea in children
Antje Körner

10:30–11:00 Journal club on previous lecture topic
11:15–12:45 Cardiac sequelae of obesity–development, prevalence and intervention
Sandra Erbs
12:45–13:15 Journal club on previous lecture topic
14:15–15:45 Healthy and unhealthy obesity
Matthias Blüher
 15:45–16:15 Journal club on previous lecture topic

Tuesday, 29 November 2016


Presentation of patients in the Children's Hospital
Maria Schlanstein



Mathias FaßhauerJournal club on previous lecture topic
11:45–12:15 Journal club on previous lecture topic

Wednesday, 30 November 2016


Obesity and psoriasis
Anja Saalbach

10:30–11:30 Presentation of patients in the Heart Center Leipzig
Sandra Erbs


Thursday, 1 December 2016

09:00–10:30 Treatment of diabetes
Anke Tönjes
10:30–11:00 Journal club on previous lecture topic

Set up:

Every participant of the course will prepare one of the pre-selected scientific articles and present it during one of the journal clubs.

Maximum number of participants: 20

Credit points: 1 (non-graded)

Venue: Rudolf Schönheimer Institute of Biochemistry, Johannisallee 30

If you want to attend the seminar, please register until 10 November by sending an e-mail to Anja Pohl.