Curriculum 2014

31.3. - 04.03. IRTG module: Animal Models in Obesity
03. - 04.04. Course "Safety Aspects in Gene Technology"
28. - 30.04. IRTG module: Prinzciples of clinical studies
23. - 24.05. CRC-retreat in Oppurg
10. - 13.06. IRTG module: Protein expression, purification and characterization
28.09.- 1.10 Summer school
28.11.–29.11.
CRC retreat in Oppurg
09.12-12.12. IRTG module: Statistics and Bioinformatics

 

Principles of clinical studies

"Principles of clinical studies"

Schedule

Monday, 28th April

09:00 – 10:00 Einführung: Überblick Studiendesigns
Oana Brosteanu
10:00 – 11:00 Vorstellung der ADIPO-VENT-Studie
N. N.
11:20 – 12:20 Allgemeine Hinweise zur Prüfplanerstellung
Oana Brosteanu/David Petroff
13:00 – 14:30 Studienplanung und Studiendesign am Beispiel der ADIPO-VENT-Studie I
Oana Brosteanu/David Petroff
14:45 – 16:15 Studienplanung und Studiendesign am Beispiel der ADIPO-VENT-Studie II
Oana Brosteanu/David Petroff

Thuesday, 29th April

09:00 – 10:30

Rechtliche Grundlagen klinischer Studien
Peggy Houben

10:50 – 12:20

Aufgaben der Ethikkommission in klinischen Studien
Michael Schaefer

13:00 – 14:00

Patienteninformation und Datenschutz
Peggy Houben

14:00 – 15:00

Dokumentation klinischer Studien
Bianca Scholze

15:15 – 16:15

Umgang mit unerwünschten Ereignissen
Peggy Houben

Wednesday, 30th April

09:00 – 10:00 Vorstellung Studie II: Exanatide-Studien
Haiko Schlögl
10:00 – 11:00 Vorstellung Studie III: Adipositasprävention und -therapie bei Kindern: T.A.F.F.- und KLAKS-Studie
Susann Blüher
11:30 – 13:00 Vorstellung des LANCET-Sonderbands "Verbesserungsmöglichkeiten und Defizite in der Gesundheitsforschung"
Oana Brosteanu

Monday, 12th May

09:00 – 10:00 Abschlussklausur


Notice:

Max. participants: 20

Credit points: 2 (benotet)

Venue: Zentrum für Klinische Studien Leipzig, Härtelstraße 16 - 18

Protein expression, -purification and characterization

Protein expression, -purification and characterization

This course introduces modern techniques of recombinant expression and purification of proteins, including expression in E.coli as well as eukaryotic expression systems. Special attention will be given to adipocytokines. Analysis will include spectroscopic methods (mass spectrometry, 3D structure analysis methods) and cell based signalling tools. The seminar will take place in Leipzig from 10 to 13 June 2014.

Schedule

10 June 2014
09:00–10:30 Lecture: Protein crystallization–not just trial and error
Norbert Sträter
10:45–12:15 Lecture: X-ray structure determination–walking around in electron density
Norbert Sträter
12:15–13:15 Practical course: Crystallography
Norbert Sträter

 

11 June 2014

09:00–10:30/
10:45–12:15

Lecture: Cloning, protein expression and purification
Annette Beck-Sickinger
12:15–13:15 Guided lab tour
Annette Beck-Sickinger

 

12 June 2014

09:00–10:30

Lecture: Protein analytics
John Heiker

10:45–12:15 

Lecture: Mass spectrometry
John Heiker
12:15–13:15 Practical demonstration: Mass spectrometry
John Heiker

 

13 June 2014

09:00–10:00

Lecture: Introduction to NMR (part 1)
Stephan Theisgen

10:00–11:00 

Practical course: Recording of NMR spectra
Stephan Theisgen/Georg Künze
11:00–12:00 Lecture: Introduction to NMR (part 2)
Stephan Theisgen
12:00–13:00 Practical course: Analysis of NMR spectra
Stephan Theisgen/Georg Künze

 

24 June 2014

09:00–10:00

Final exam (written)

Set up:
Maximum number of participants: 12
Credit points: 2 (graded)
Venue: Institute of Biochemistry (Brüderstraße 34, Tuesday–Thursday) and Institute of Biophysics and Medical Physics (Härtelstraße 16–18, Friday)

 

Please register for the course by sending an e-mail to Anja Pohl until 26 May