Recently published- Joint CRC publication

A muscle protein at work in brown adipose tissue

Brown adipose tissue is a metabolically active organ that transfers energy from fat into heat. Heat production from BAT is activated whenever the organism needs extra heat, e.g. during cold-exposure, postnatally, during entry into a febrile state or during arousal from hibernation. Its main function is to maintain body temperature. For a long time, it was assumed that this tissue regresses with increasing age and is completely lost by the time a person reaches adulthood. But this view was refuted and the capacity to produce brown adipose tissue has been shown in adulthood 〈...〉


Christen L, Broghammer H, Rapöhn I, et al. Myoglobin-mediated lipid shuttling increases adrenergic activation of brown and white adipocyte metabolism and is as a marker of thermogenic adipocytes in humans. Clin Transl Med. 2022; 12:e1108.